Detailed information NTG0252933

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: CS376_RS18475
• Genome accession: NZ_CP024203
• Coordinates: 3652429..3653592 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain NKG-1
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3647429..3658592

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CS376_RS18445	-	3647693..3648112 (-)	420	WP_025285352.1	TIGR03826 family flagellar region protein	-
CS376_RS18450	comFC	3648186..3648875 (-)	690	WP_217898730.1	phosphoribosyltransferase family protein	Machinery gene
CS376_RS18455	-	3648881..3649165 (-)	285	WP_007407481.1	late competence development ComFB family protein	-
CS376_RS18460	comFA	3649223..3650608 (-)	1386	WP_094032535.1	DEAD/DEAH box helicase	Machinery gene
CS376_RS18465	-	3650717..3651565 (-)	849	WP_003151387.1	DegV family protein	-
CS376_RS18470	degU	3651663..3652352 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
CS376_RS18475	degS	3652429..3653592 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
CS376_RS18480	-	3653815..3654462 (+)	648	WP_076424607.1	YigZ family protein	-
CS376_RS18485	-	3654467..3655687 (+)	1221	WP_012118574.1	LCP family protein	-
CS376_RS18490	-	3655786..3656862 (-)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
CS376_RS18495	tuaH	3656995..3658191 (-)	1197	WP_076424609.1	teichuronic acid biosynthesis protein TuaH	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=252933 CS376_RS18475 WP_007407484.1 3652429..3653592(-) (degS) [Bacillus velezensis strain NKG-1]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=252933 CS376_RS18475 WP_007407484.1 3652429..3653592(-) (degS) [Bacillus velezensis strain NKG-1]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951