Detailed information NTG0021169

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: NGO_RS09375
• Genome accession: NC_002946
• Coordinates: 1834898..1836085 (-)
• Length: 395 a.a.
• NCBI ID: WP_003705341.1
• Uniprot ID: Q5F5Q2
• Organism: Neisseria gonorrhoeae FA 1090
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1829898..1841085

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NGO_RS09355 (NGO1861a)	-	1830206..1831042 (-)	837	WP_164920418.1	opacity family porin	-
NGO_RS09360 (NGO_09970)	-	1831144..1831688 (-)	545	Protein_1842	IS1595 family transposase	-
NGO_RS12285	-	1831678..1831806 (-)	129	Protein_1843	phosphomethylpyrimidine synthase ThiC	-
NGO_RS09365 (NGO1863)	topA	1832027..1834333 (-)	2307	WP_003705339.1	type I DNA topoisomerase	-
NGO_RS09370 (NGO1864)	-	1834411..1834872 (-)	462	WP_003690120.1	DUF494 domain-containing protein	-
NGO_RS09375 (NGO1865)	dprA	1834898..1836085 (-)	1188	WP_003705341.1	DNA-processing protein DprA	Machinery gene
NGO_RS09380 (NGO1866)	-	1836176..1837453 (-)	1278	WP_003690124.1	sigma-54-dependent transcriptional regulator	-
NGO_RS09385 (NGO1867)	-	1837446..1839566 (-)	2121	WP_003690126.1	HAMP domain-containing histidine kinase	-
NGO_RS09390 (NGO1868)	-	1839566..1840165 (-)	600	WP_003690128.1	DUF4390 domain-containing protein	-

Sequence

Protein

• Length: 395 a.a.
• Molecular weight: 41852.92 Da
• Isoelectric Point: 6.3096

>NTDB_id=21169 NGO_RS09375 WP_003705341.1 1834898..1836085(-) (dprA) [Neisseria gonorrhoeae FA 1090]
MTEDERFAWLQLAFTPYIGAESFLLLMRSFGSAQNALSAPAEQVAPAVRHKHALEAWRNAEKRALARQAAEAALEWEMRD
GCRLMLLQDEDFPEMLTQGLTAPPVLFLRGNVRLLHKPSAAIVGSRHATPQAMRIAKDFGRALGGKGIPTVSGMASGIDT
AAHQGALEAEGGTVAVWGTGIDRIYPPANKNLAYEIAEKGLIVSEFPIGTRPYAGNFPRRNRLIAALSQVTLVVEAALES
GSLITAGLAAEMGREVMAVPGSIDNPHSKGCHKLIKDGAKLTECLDDILNECPGLLQNTGASSYSINKDTPDTGRRAVQT
AYAPPPAAKMPSEGAAGGTAVGGILDKMGFDPVHPDVLAGQLAMPAADLYAALLELELDGSVAAMPGGRYQRIRT

Nucleotide

• Length: 1188 bp

>NTDB_id=21169 NGO_RS09375 WP_003705341.1 1834898..1836085(-) (dprA) [Neisseria gonorrhoeae FA 1090]
ATGACAGAGGACGAACGTTTCGCGTGGCTGCAATTGGCGTTTACGCCCTATATCGGCGCGGAAAGTTTCCTGCTGCTGAT
GCGCAGTTTCGGCAGCGCGCAAAATGCCTTGTCCGCACCGGCGGAACAGGTTGCCCCGGCGGTGCGGCATAAGCACGCGC
TTGAGGCTTGGCGCAATGCGGAAAAACGCGCTTTGGCGCGGCAGGCGGCAGAAGCGGCGTTGGAATGGGAAATGCGGGAC
GGATGCCGCCTGATGCTGCTTCAGGATGAAGATTTCCCCGAAATGCTGACGCAGGGGCTGACCGCGCCGCCGGTTTTGTT
TTTGCGCGGCAACGTGCGGCTGCTGCACAAGCCTTCCGCCGCCATCGTCGGCAGCCGCCATGCCACGCCGCAGGCGATGC
GGATTGCCAAAGATTTCGGCAGGGCGTTGGGTGGGAAAGGCATTCCTACCGTGTCGGGTATGGCTTCGGGCATCGACACC
GCCGCCCATCAGGGCGCACTGGAGGCAGAAGGCGGCACCGTCGCCGTGTGGGGGACGGGCATAGACCGCATTTATCCGCC
GGCCAACAAAAACCTTGCCTATGAAATCGCCGAAAAAGGGCTGATTGTCAGCGAGTTCCCCATCGGCACGCGGCCGTATG
CCGGCAACTTTCCGCGCCGCAACCGCCTGATTGCCGCGCTGTCGCAGGTTACGCTGGTGGTCGAGGCCGCCTTGGAATCC
GGTTCGCTGATTACCGCCGGCCTGGCGGCAGAAATGGGGCGCGAAGTGATGGCGGTACCCGGTTCGATAGACAACCCCCA
CAGCAAAGGCTGCCACAAACTGATTAAAGACGGAGCGAAACTGACGGAATGTTTGGACGACATCCTGAACGAATGCCCGG
GGCTATTGCAAAATACGGGTGCTTCGTCATATTCTATAAATAAGGATACGCCCGACACGGGCCGCCGCGCCGTTCAGACG
GCATACGCCCCGCCGCCTGCCGCAAAAATGCCGTCTGAAGGGGCGGCAGGCGGCACAGCCGTCGGCGGCATACTGGATAA
AATGGGTTTCGACCCGGTTCATCCCGACGTGCTTGCCGGACAGTTGGCTATGCCTGCCGCAGATTTGTATGCCGCACTGT
TGGAATTGGAATTGGACGGCAGCGTTGCCGCAATGCCCGGCGGCAGATACCAGCGTATCCGAACTTGA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (79-282)

• DprA winged helix domain (DprA_WH) (341-388)

3D structure

• AlphaFold DB: Q5F5Q2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Neisseria gonorrhoeae strain FA1090	100	100	1
dprA	Neisseria gonorrhoeae MS11	99.241	100	0.992
dprA	Neisseria meningitidis strain C311	90.176	100	0.906
dprA	Neisseria meningitidis MC58	90.176	100	0.906
dprA	Vibrio cholerae strain A1552	37.531	100	0.377