Detailed information NTG0150419

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: AXW93_RS02385
• Genome accession: NZ_CP014866
• Coordinates: 504123..506921 (+)
• Length: 932 a.a.
• NCBI ID: WP_003117917.1
• Uniprot ID: -
• Organism: Pseudomonas aeruginosa strain PA_154197
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 499123..511921

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AXW93_RS02360 (AXW93_02275)	dbpA	499604..500980 (-)	1377	WP_003084703.1	ATP-dependent RNA helicase DbpA	-
AXW93_RS02365 (AXW93_02280)	-	501328..501537 (+)	210	WP_003084710.1	cold-shock protein	-
AXW93_RS02370 (AXW93_02285)	-	501688..502212 (+)	525	WP_003113272.1	ATP-dependent zinc protease	-
AXW93_RS02375 (AXW93_02290)	mdtD	502315..503748 (-)	1434	WP_003084717.1	multidrug transporter subunit MdtD	-
AXW93_RS02385 (AXW93_02295)	clpC	504123..506921 (+)	2799	WP_003117917.1	AAA family protein disaggregase ClpG	Regulator
AXW93_RS02390 (AXW93_02300)	-	507023..507601 (+)	579	WP_003084725.1	DUF2780 domain-containing protein	-
AXW93_RS02395 (AXW93_02305)	-	507920..508807 (-)	888	WP_003099939.1	acyltransferase	-
AXW93_RS02400 (AXW93_02310)	-	508950..509459 (+)	510	WP_003113269.1	ATP-dependent zinc protease	-
AXW93_RS02405 (AXW93_02315)	creB	509544..510233 (+)	690	WP_003113268.1	two-component system response regulator CreB	-
AXW93_RS02410 (AXW93_02320)	creC	510233..511657 (+)	1425	WP_003113267.1	two-component system sensor histidine kinase CreC	-

Sequence

Protein

• Length: 932 a.a.
• Molecular weight: 103409.94 Da
• Isoelectric Point: 6.8717

>NTDB_id=150419 AXW93_RS02385 WP_003117917.1 504123..506921(+) (clpC) [Pseudomonas aeruginosa strain PA_154197]
MAQELCAICHERPAVARVSLVQNGQRRELALCELHYRQLMRQQRMRSPLESLFGGGSPFDEIFSGFGEQSPVTPVRAREP
EAVDIAEYFSKQTTEYLQRAAQVAAEFGKREVDTEHLLYALADADVVQAVLKQFGLSPADLKQYIEANAVRGASKGEASE
DMTISPRVKSALQHAFALSRELGHSYVGPEHLLLGLAAVPDSFAGTLLKKYGLTEQALRQKAVKVVGKGAEDGRVDGPSN
TPQLDKFSRDLTRLAREGKLDPVIGRSKEVETTIEVLARRKKNNPVLIGEPGVGKTAIVEGLAQRMVQGEVPEVLRDKRL
VELNINAMVAGAKYRGEFEERLKQVMDELQAAQSEIILFIDEVHTIVGAGQGGGEGGLDVANVLKPAMARGEMNLIGATT
LNEYQKYIEKDAALERRFQPVFVPEPTVEQTISILRGLRDKLEGHHKVTIRDEAFVAAAELSDRYIGNRFLPDKAIDLID
QAAARVRIASTSRPAEIQELEAELAQLKREQDYAASRKWYDEAKVFEKRIQERKEHLEQITERWQQTQGSKTEEVRVEDI
AEIISRLTGIPVTELTAEEREKLLQMEERLHQRVIGQQEAITAVSDAVRLARAGLRQGSRPIATFLFLGPTGVGKTELAK
ALAEVVFGDEDAMIRIDMSEYMERHAVSRLIGAPPGYVGYDEGGQLTERVRRRPYSVILLDEIEKAHADVNNILLQVFDD
GRLTDGKGRVVDFTNTIIIATSNLGSELIMKNAQAGEFAQPPEKLKRELMTTLRGHFRPEFLNRLDEVIVFESLSKAQIE
DIVRLQLERVKRAAHAQDIYLHIDDSLVGHLAEEAYQPEFGARELKRQIRQQLETRLATAMLKGEVKEGETVTFFYDAKD
GVGYRKGAAPKPAARKKSGAGETPKGRATAARKPAAKKGAAAKGKADKPKAK

Nucleotide

• Length: 2799 bp

>NTDB_id=150419 AXW93_RS02385 WP_003117917.1 504123..506921(+) (clpC) [Pseudomonas aeruginosa strain PA_154197]
ATGGCCCAGGAACTTTGCGCTATCTGCCACGAACGTCCCGCCGTCGCCCGCGTCAGCCTGGTACAGAACGGCCAGCGCCG
CGAACTCGCCCTCTGCGAACTGCACTACCGCCAGTTGATGCGCCAGCAGCGCATGCGCTCGCCGCTGGAGTCGCTGTTCG
GCGGCGGCAGCCCGTTCGACGAGATCTTCTCCGGCTTCGGCGAGCAGAGCCCGGTCACCCCGGTGCGCGCCCGCGAGCCG
GAGGCGGTGGACATCGCCGAGTACTTCAGCAAGCAGACCACCGAGTACCTGCAACGCGCCGCGCAGGTCGCCGCCGAATT
CGGCAAGCGCGAAGTGGACACCGAGCACCTGCTCTACGCCCTGGCCGACGCCGACGTGGTGCAGGCGGTGCTCAAGCAGT
TCGGCCTGTCGCCGGCCGACCTCAAGCAGTACATCGAGGCCAACGCCGTGCGCGGCGCCAGCAAGGGCGAGGCGAGCGAG
GACATGACCATCTCGCCACGGGTGAAGAGCGCCTTGCAGCATGCCTTCGCCCTGTCCCGCGAACTCGGCCACAGCTATGT
CGGCCCCGAGCACCTGTTGCTCGGCCTGGCGGCGGTGCCGGACAGCTTCGCCGGGACGCTCCTGAAGAAGTACGGCCTGA
CCGAGCAGGCGCTACGGCAGAAAGCGGTCAAGGTGGTCGGCAAGGGCGCCGAGGACGGCCGCGTGGACGGCCCGAGCAAC
ACTCCGCAACTGGACAAGTTCAGCCGCGACCTGACCCGGCTGGCCCGCGAAGGCAAGCTCGATCCGGTGATCGGCCGCTC
GAAGGAAGTCGAGACCACCATCGAGGTTCTCGCCCGGCGCAAGAAGAACAACCCGGTGCTGATCGGCGAGCCCGGCGTCG
GCAAGACCGCCATCGTCGAAGGCCTGGCCCAGCGCATGGTCCAGGGCGAGGTGCCGGAGGTGCTGCGCGACAAGCGCCTG
GTCGAACTGAACATCAACGCCATGGTCGCCGGCGCCAAGTACCGCGGCGAGTTCGAGGAACGCCTCAAGCAGGTGATGGA
CGAACTGCAGGCGGCGCAGAGCGAGATCATCCTGTTCATCGACGAGGTGCACACCATCGTCGGTGCCGGCCAGGGCGGCG
GCGAAGGCGGGCTGGACGTGGCCAACGTGCTGAAGCCGGCGATGGCGCGCGGCGAGATGAACCTGATCGGCGCCACCACC
CTCAACGAGTACCAGAAGTACATCGAGAAGGACGCCGCGCTGGAGCGGCGCTTCCAGCCGGTGTTCGTCCCCGAGCCGAC
GGTGGAGCAGACCATCTCCATCCTCCGTGGCCTGCGCGACAAGCTCGAAGGCCACCACAAGGTGACCATCCGCGACGAGG
CCTTCGTCGCCGCCGCCGAGCTGTCCGACCGCTACATCGGCAACCGCTTCCTGCCGGACAAGGCCATCGACCTGATCGAC
CAGGCCGCCGCCCGCGTGCGCATCGCCAGCACCTCGCGGCCGGCCGAGATCCAGGAACTGGAGGCCGAGCTGGCGCAGCT
CAAGCGCGAGCAGGACTACGCCGCCAGCCGCAAGTGGTACGACGAGGCGAAGGTCTTCGAGAAACGCATCCAGGAACGCA
AGGAACACCTCGAGCAGATCACCGAGCGCTGGCAGCAGACCCAGGGGTCGAAGACCGAGGAGGTGCGGGTCGAGGACATC
GCCGAGATCATCTCCAGGCTCACCGGCATCCCGGTCACCGAACTGACCGCCGAGGAGCGCGAGAAGCTCCTGCAGATGGA
AGAGCGCCTGCACCAGCGGGTGATCGGCCAGCAGGAAGCGATCACCGCGGTCAGCGACGCCGTGCGCCTGGCCCGCGCCG
GGCTGCGCCAGGGCAGCCGGCCGATCGCCACCTTCCTGTTCCTCGGCCCGACCGGGGTGGGCAAGACCGAGCTGGCCAAG
GCCCTGGCCGAGGTGGTGTTCGGCGACGAAGACGCGATGATCCGCATCGACATGAGCGAATACATGGAGCGCCACGCGGT
GTCCCGGCTGATCGGTGCGCCGCCGGGCTACGTCGGCTACGACGAGGGCGGCCAGCTCACCGAGCGGGTGCGCCGGCGGC
CTTACAGCGTGATCCTGCTCGACGAGATCGAGAAGGCCCACGCCGACGTCAACAACATCCTCCTGCAGGTGTTCGACGAC
GGCCGCCTGACCGACGGCAAGGGGCGCGTGGTGGACTTCACCAACACCATCATCATCGCCACCAGCAACCTAGGCTCCGA
GCTGATCATGAAGAACGCCCAGGCCGGCGAGTTCGCCCAGCCGCCGGAGAAGCTCAAGCGCGAACTGATGACTACCCTGC
GCGGACATTTCCGCCCGGAATTCCTCAACCGCCTCGACGAGGTGATCGTCTTCGAGTCGCTGAGCAAGGCGCAGATCGAG
GACATCGTGCGCCTGCAACTGGAGCGGGTGAAGCGCGCCGCGCACGCTCAGGACATCTACCTGCACATCGACGACAGCCT
GGTCGGCCACCTCGCCGAAGAGGCCTACCAGCCGGAGTTCGGCGCCCGCGAGCTGAAGCGGCAGATCCGCCAGCAACTGG
AGACGCGCCTGGCCACGGCGATGCTCAAGGGCGAGGTGAAAGAGGGCGAGACGGTCACCTTCTTCTACGACGCCAAGGAC
GGCGTCGGCTACCGCAAGGGCGCCGCGCCGAAGCCGGCGGCACGCAAGAAATCCGGCGCCGGCGAGACGCCCAAGGGCCG
CGCGACGGCGGCGAGGAAGCCGGCGGCGAAGAAAGGCGCCGCCGCCAAGGGCAAGGCCGACAAGCCGAAGGCCAAGTGA

Domains

Predicted by InterProScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (100-147)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (175-226)

• AAA domain (Cdc48 subfamily) (AAA_2) (620-788)

• ATPase family associated with various cellular activities (AAA) (AAA) (286-419)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (794-873)

• AAA lid domain (AAA_lid_9) (427-524)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	50.374	86.052	0.433
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	45.113	85.622	0.386
clpC	Streptococcus thermophilus LMD-9	42.805	88.734	0.38
clpC	Streptococcus thermophilus LMG 18311	42.563	88.734	0.378
clpC	Streptococcus mutans UA159	41.383	88.412	0.366