Detailed information
Bioinformatically predicted
Overview
| Name | comGC/cglC | Type | Machinery gene |
| Locus tag | ACLV7A_RS01090 | Genome accession | NZ_OZ217344 |
| Coordinates | 210476..210799 (+) | Length | 107 a.a. |
| NCBI ID | WP_000738649.1 | Uniprot ID | - |
| Organism | Streptococcus mitis isolate S. mitis E22 | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
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Genomic Context
Location: 205476..215799
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ACLV7A_RS01065 (SMIE22_02060) | nagA | 205607..206758 (+) | 1152 | WP_218757951.1 | N-acetylglucosamine-6-phosphate deacetylase | - |
| ACLV7A_RS01070 (SMIE22_02070) | - | 206921..207979 (+) | 1059 | WP_084886478.1 | zinc-dependent alcohol dehydrogenase family protein | - |
| ACLV7A_RS01075 (SMIE22_02080) | - | 208129..208494 (+) | 366 | WP_045606653.1 | DUF1033 family protein | - |
| ACLV7A_RS01080 (SMIE22_02090) | comGA/cglA/cilD | 208569..209510 (+) | 942 | WP_411863363.1 | competence type IV pilus ATPase ComGA | Machinery gene |
| ACLV7A_RS01085 (SMIE22_02100) | comGB/cglB | 209458..210474 (+) | 1017 | WP_411864201.1 | competence type IV pilus assembly protein ComGB | Machinery gene |
| ACLV7A_RS01090 (SMIE22_02110) | comGC/cglC | 210476..210799 (+) | 324 | WP_000738649.1 | competence type IV pilus major pilin ComGC | Machinery gene |
| ACLV7A_RS01095 (SMIE22_02120) | comGD/cglD | 210762..211196 (+) | 435 | WP_411863364.1 | competence type IV pilus minor pilin ComGD | Machinery gene |
| ACLV7A_RS01100 (SMIE22_02130) | comGE/cglE | 211159..211461 (+) | 303 | WP_000413380.1 | competence type IV pilus minor pilin ComGE | Machinery gene |
| ACLV7A_RS01105 (SMIE22_02140) | comGF/cglF | 211424..211885 (+) | 462 | WP_000250514.1 | competence type IV pilus minor pilin ComGF | Machinery gene |
| ACLV7A_RS01110 (SMIE22_02150) | comGG/cglG | 211863..212276 (+) | 414 | WP_411863365.1 | competence type IV pilus minor pilin ComGG | Machinery gene |
| ACLV7A_RS01115 (SMIE22_02160) | - | 212309..212896 (+) | 588 | WP_411863366.1 | class I SAM-dependent methyltransferase | - |
| ACLV7A_RS01120 (SMIE22_02170) | comYH | 212957..213910 (+) | 954 | WP_411863367.1 | class I SAM-dependent methyltransferase | Machinery gene |
| ACLV7A_RS01125 (SMIE22_02180) | - | 213961..215151 (+) | 1191 | WP_000167777.1 | acetate kinase | - |
| ACLV7A_RS01130 (SMIE22_02190) | rnpA | 215299..215670 (+) | 372 | WP_000739245.1 | ribonuclease P protein component | - |
Sequence
Protein
Download Length: 107 a.a. Molecular weight: 12084.29 Da Isoelectric Point: 10.0527
>NTDB_id=1170254 ACLV7A_RS01090 WP_000738649.1 210476..210799(+) (comGC/cglC) [Streptococcus mitis isolate S. mitis E22]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLLLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLNKNEEATLSKLQA
DDRITEEQAKAYKEYHAKQNKTQTVAD
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLLLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLNKNEEATLSKLQA
DDRITEEQAKAYKEYHAKQNKTQTVAD
Nucleotide
Download Length: 324 bp
>NTDB_id=1170254 ACLV7A_RS01090 WP_000738649.1 210476..210799(+) (comGC/cglC) [Streptococcus mitis isolate S. mitis E22]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTCACTCTGGTAGAGATGTTAGTGGTCCTTTTAAT
CATCAGCGTGCTTCTCTTGCTCTTTGTACCTAATTTGACCAAGCAAAAAGAAGCAGTCAACGACAAAGGAAAAGCTGCTG
TTGTTAAGGTGGTAGAAAGCCAGGCAGAGCTTTATAGTTTGAATAAAAACGAAGAGGCTACTCTAAGCAAATTACAAGCA
GATGATCGCATCACAGAAGAGCAAGCTAAAGCTTATAAAGAATATCATGCAAAACAAAATAAGACTCAAACAGTTGCAGA
TTAA
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTCACTCTGGTAGAGATGTTAGTGGTCCTTTTAAT
CATCAGCGTGCTTCTCTTGCTCTTTGTACCTAATTTGACCAAGCAAAAAGAAGCAGTCAACGACAAAGGAAAAGCTGCTG
TTGTTAAGGTGGTAGAAAGCCAGGCAGAGCTTTATAGTTTGAATAAAAACGAAGAGGCTACTCTAAGCAAATTACAAGCA
GATGATCGCATCACAGAAGAGCAAGCTAAAGCTTATAAAGAATATCATGCAAAACAAAATAAGACTCAAACAGTTGCAGA
TTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comGC/cglC | Streptococcus mitis NCTC 12261 |
94.393 |
100 |
0.944 |
| comGC/cglC | Streptococcus mitis SK321 |
92 |
93.458 |
0.86 |
| comGC/cglC | Streptococcus pneumoniae Rx1 |
91 |
93.458 |
0.85 |
| comGC/cglC | Streptococcus pneumoniae D39 |
91 |
93.458 |
0.85 |
| comGC/cglC | Streptococcus pneumoniae R6 |
91 |
93.458 |
0.85 |
| comGC/cglC | Streptococcus pneumoniae TIGR4 |
90 |
93.458 |
0.841 |
| comYC | Streptococcus gordonii str. Challis substr. CH1 |
70.476 |
98.131 |
0.692 |
| comYC | Streptococcus mutans UA140 |
67.308 |
97.196 |
0.654 |
| comYC | Streptococcus mutans UA159 |
67.308 |
97.196 |
0.654 |
| comYC | Streptococcus suis isolate S10 |
71.605 |
75.701 |
0.542 |
| comGC | Lactococcus lactis subsp. cremoris KW2 |
55.67 |
90.654 |
0.505 |
| comGC | Staphylococcus aureus MW2 |
48.837 |
80.374 |
0.393 |
| comGC | Staphylococcus aureus N315 |
48.837 |
80.374 |
0.393 |