Detailed information NTG1141474

Bioinformatically predicted

Overview

• Name: comR/comR2
• Type: Regulator
• Locus tag: DQN42_RS08625
• Genome accession: NZ_LS483436
• Coordinates: 1748833..1749306 (-)
• Length: 157 a.a.
• NCBI ID: WP_014829824.1
• Uniprot ID: -
• Organism: Streptococcus intermedius strain NCTC11324
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	1741030..1749306	1748833..1749306	within	0

Gene organization within MGE regions

Location: 1741030..1749306

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN42_RS08530 (NCTC11324_01717)	-	1741030..1741437 (+)	408	WP_003073927.1	pyridoxamine 5'-phosphate oxidase family protein	-
DQN42_RS08535 (NCTC11324_01718)	-	1741467..1741785 (-)	319	Protein_1645	winged helix-turn-helix transcriptional regulator	-
DQN42_RS08540 (NCTC11324_01719)	-	1741898..1742359 (+)	462	Protein_1646	tyrosine-type recombinase/integrase	-
DQN42_RS08625 (NCTC11324_01736)	comR/comR2	1748833..1749306 (-)	474	WP_014829824.1	hypothetical protein	Regulator

Sequence

Protein

• Length: 157 a.a.
• Molecular weight: 19347.33 Da
• Isoelectric Point: 7.8842

>NTDB_id=1141474 DQN42_RS08625 WP_014829824.1 1748833..1749306(-) (comR/comR2) [Streptococcus intermedius strain NCTC11324]
MDFKELYEKVRGIVLKCRREYYVHLWELSDWDQEGMIVLYELVSCHPYLVEEEAHLYVYYKTKFRNHIKDILRKQESQKR
KLDRQVYEEVSEIGHKLSLKGLYLDELVILRDQLKSYQKQLSPAKQEQYERLLADERFKGRQAMLRELRTYLKDYEM

Nucleotide

• Length: 474 bp

>NTDB_id=1141474 DQN42_RS08625 WP_014829824.1 1748833..1749306(-) (comR/comR2) [Streptococcus intermedius strain NCTC11324]
ATGGATTTCAAGGAGTTATATGAGAAAGTAAGGGGAATTGTGCTGAAGTGTCGGCGGGAATATTATGTCCATCTGTGGGA
GCTAAGCGATTGGGATCAAGAAGGGATGATAGTCTTGTATGAGTTGGTAAGTTGCCACCCCTATTTGGTAGAGGAAGAAG
CCCATCTCTATGTCTACTATAAGACAAAGTTTCGGAATCACATAAAGGATATTCTGCGCAAACAAGAAAGTCAAAAGCGC
AAACTGGATCGCCAAGTGTATGAAGAGGTAAGTGAGATTGGGCACAAGTTAAGTCTGAAAGGTCTGTATCTAGACGAGTT
GGTAATACTCCGCGATCAATTAAAGTCCTATCAAAAGCAACTGAGTCCCGCCAAGCAAGAGCAGTATGAGCGGTTACTGG
CAGATGAAAGGTTCAAAGGCCGCCAAGCGATGCTTCGAGAGTTACGAACCTACTTAAAAGACTATGAGATGTAG

Domains

No domain identified.

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	60.645	98.726	0.599
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	60.645	98.726	0.599
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	56.774	98.726	0.561
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	55.484	98.726	0.548
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	54.839	98.726	0.541
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	54.839	98.726	0.541
comX/comX1	Streptococcus pneumoniae D39	54.194	98.726	0.535
comX/comX1	Streptococcus pneumoniae R6	54.194	98.726	0.535
comX/comX2	Streptococcus pneumoniae R6	54.194	98.726	0.535
comX/comX2	Streptococcus pneumoniae Rx1	54.194	98.726	0.535
comX/comX1	Streptococcus pneumoniae Rx1	54.194	98.726	0.535
comX/comX2	Streptococcus pneumoniae D39	54.194	98.726	0.535
comX/comX1	Streptococcus pneumoniae TIGR4	53.548	98.726	0.529
comX/comX2	Streptococcus pneumoniae TIGR4	53.548	98.726	0.529
comX/sigX	Streptococcus mutans UA159	50.649	98.089	0.497
comX/sigX	Streptococcus suis D9	48.387	98.726	0.478
comX/sigX	Streptococcus suis isolate S10	48.387	98.726	0.478
comX/sigX	Streptococcus suis P1/7	48.387	98.726	0.478
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	43.226	98.726	0.427
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	43.226	98.726	0.427
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	43.226	98.726	0.427
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	43.226	98.726	0.427
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	43.226	98.726	0.427
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	43.226	98.726	0.427
comX	Streptococcus salivarius SK126	42.208	98.089	0.414
comX/sigX	Streptococcus salivarius strain HSISS4	41.558	98.089	0.408
comX	Streptococcus thermophilus LMG 18311	41.558	98.089	0.408
comX	Streptococcus thermophilus LMD-9	41.558	98.089	0.408
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	40.385	99.363	0.401