Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS00302  |
| T6SS type | Type i1 |
| Strain | Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853 |
| Replicon (RefSeq) | chromosome (NC_011205) |
| Location | 1206170..1229487 |
| Function | - |
| Comment | - |
| References | [1] Pezoa D et al (2014) Only one of the two type VI secretion systems encoded in the Salmonella enterica serotype Dublin genome is involved in colonization of the avian and murine hosts. Vet Res. 45(1):2. [PudMed:24405577] [2] Blondel CJ et al (2009) Comparative genomic analysis uncovers 3 novel loci encoding type six secretion systems differentially distributed in Salmonella serotypes. BMC Genomics. 0.6625. [PudMed:19653904] |
Bioinformatics investigation has been performed.T6SS components and genome coordinates
| Component | FHA | PAAR | TssA | TssB | TssC | TssD | TssE | TssF | TssG | TssH | TssI | TssJ | TssK | TssL | TssM |
| Number | 1 | 1 | 2 | 1 | 2 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| SED_RS06200 | 1201427..1202533 | + | 1107 | WP_000988586.1 | Gfo/Idh/MocA family oxidoreductase | ||
| SED_RS06205 | 1202700..1202993 | - | 294 | WP_000114401.1 | hypothetical protein | ||
| SED_RS06210 | 1203024..1203242 | + | 219 | WP_000880617.1 | hypothetical protein | ||
| SED_RS06220 | 1203843..1204301 | - | 459 | WP_000623372.1 | DUF1311 domain-containing protein | ||
| SED_RS06225 | 1204425..1204796 | - | 372 | WP_001675823.1 | hypothetical protein | ||
| SED_RS06230 | 1204805..1205245 | - | 441 | WP_001022121.1 | hypothetical protein | ||
| SED_RS06235 | 1205265..1206137 | - | 873 | WP_000248210.1 | LysM peptidoglycan-binding domain-containing protein | ||
| T6CP008711 | TssD | SED_RS06240 | 1206170..1206649 | - | 480 | WP_001284963.1 | Hcp family type VI secretion system effector |
| T6CP008712 | TssA | SED_RS06245 | 1206665..1208029 | - | 1365 | WP_000076066.1 | type VI secretion system ImpA family N-terminal domain-containing protein |
| T6CP003071 | TssM | SED_RS06250 (tssM) | 1208040..1211501 | - | 3462 | WP_001137104.1 | type VI secretion system membrane subunit TssM |
| T6CP008713 | TssA | SED_RS06255 (tssA) | 1211580..1212992 | - | 1413 | WP_000365803.1 | type VI secretion system protein TssA |
| SED_RS06260 (tagO) | 1212994..1213731 | - | 738 | WP_000089148.1 | type VI secretion system-associated protein TagO | ||
| T6CP003072 | TssH | SED_RS06265 (tssH) | 1213728..1216463 | - | 2736 | WP_000614299.1 | type VI secretion system ATPase TssH |
| T6CP003073 | TssL | SED_RS06270 | 1216476..1217234 | - | 759 | WP_000343978.1 | type IVB secretion system protein IcmH/DotU |
| T6CP003074 | TssK | SED_RS06275 (tssK) | 1217239..1218570 | - | 1332 | WP_000246455.1 | type VI secretion system baseplate subunit TssK |
| SED_RS06280 (tssJ) | 1218573..1219076 | - | 504 | WP_124084121.1 | type VI secretion system lipoprotein TssJ | ||
| T6CP011697 | FHA | SED_RS06285 (tagH) | 1219103..1220389 | - | 1287 | WP_000796942.1 | type VI secretion system-associated FHA domain protein TagH |
| T6CP003076 | TssG | SED_RS06290 (tssG) | 1220414..1221502 | - | 1089 | WP_000509049.1 | type VI secretion system baseplate subunit TssG |
| T6CP003077 | TssF | SED_RS06295 (tssF) | 1221466..1223319 | - | 1854 | WP_000393868.1 | type VI secretion system baseplate subunit TssF |
| T6CP008714 | TssE | SED_RS06300 (tssE) | 1223324..1223740 | - | 417 | WP_000611698.1 | type VI secretion system baseplate subunit TssE |
| T6CP003078 | TssC | SED_RS06305 (tssC) | 1223737..1225209 | - | 1473 | WP_000056999.1 | type VI secretion system contractile sheath large subunit |
| T6CP003080 | TssB | SED_RS06315 (tssB) | 1225500..1226003 | - | 504 | WP_000031252.1 | type VI secretion system contractile sheath small subunit |
| T6CP008715 | TssD | SED_RS06325 | 1226633..1227151 | + | 519 | WP_001142966.1 | Hcp family type VI secretion system effector |
| T6CP003081 | TssI | SED_RS06330 | 1227373..1229487 | + | 2115 | WP_000103458.1 | type VI secretion system tip protein VgrG |
| T6CP011698 | PAAR | SED_RS06335 | 1229589..1233806 | + | 4218 | WP_000014629.1 | RHS repeat protein |
| SED_RS06340 | 1233806..1234138 | + | 333 | WP_001675826.1 | hypothetical protein |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|
Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
|---|