SecReT6, T6SS database

Detailed information of component protein

Summary

Component ID	T6CP011698
Component protein type	PAAR
T6SS ID (Type)	T6SS00302 (Type i1)
Strain	Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853
Replicon	chromosome
Sequence	Protein sequence (1406 a.a.); Nucleotide sequence (4218 bp)
Reference	[1] Blondel CJ, Jiménez JC, Contreras I, et al. Comparative genomic analysis uncovers 3 novel loci encoding type six secretion systems differentially distributed in Salmonella serotypes. BMC Genomics. 2009 Aug 4;10:354. doi: 10.1186/1471-2164-10-354. PMID: 19653904 [2] Pezoa D, Blondel CJ, Silva CA, et al. Only one of the two type VI secretion systems encoded in the Salmonella enterica serotype Dublin genome is involved in colonization of the avian and murine hosts. Vet Res. 2014 Jan 9;45:2. doi: 10.1186/1297-9716-45-2. PMID: 24405577

Bioinformatics investigation has been performed on this T6SS

External database links

Locus tag (Gene)	SED_RS06335
Coordinate (Strand)	1229589..1233806 (+)
NCBI ID	445936774
RefSeq	NC_011205
Uniprot ID	-
KEGG ID	-
PDB ID	-

Pfam domain hit(s)

Domain	Pfam ID	E-value	Aligned region
DUF6531	PF20148.1	6.3e-16	49..126
RHS	PF03527.16	6e-11	1168..1203
RHS_repeat	PF05593.16	3.2e-07	591..627
RHS_repeat	PF05593.16	4.4e-06	465..498
RHS_repeat	PF05593.16	1.1e-05	505..542
RHS_repeat	PF05593.16	3.2e-05	633..668

Transmembrane helices

Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction	Region	Sequence
Outside	1-1405	MSGKPAARQGDMTQVGGPIVQGSAGVLIGAPTGVACSVCPTGEASPKYGNPVNPLLGAKVLPGETDIALPGPLPFVLSRAYSSYRTKTPAPVGLCGPGWKLPSDLWLQLRGDGLILNDNGGRSVHFEPLAPGEIQYSRSESFWLARGGAASQHNSHPLSVMWGMLPEAVRLCPHIYLATNSPQGPWWVLGWAERVPGADEALPAPLPPYRVLTGVVDGYGRRLTYHRDGAYGGAVTAVTDSTGRRYRLVLTTQAQRAAQAASASSSSLSPAPSSFPSFSSPPSPRSPSSWSETLPVTACGEDSGIRLSAVWLVEDPACPDALPSQPLVRYGYTARGELEAVYDRSGAEVRRFEYDAGQPGRMTAHRYAGRPASRYRYDDAGRVTEQVNPEGLGYAFAYEKNKITVTDSLGRREVLHTEGEGGLKRVVMKASADGSVTRSRYDASGRPEWQTDATGRKTTYSPDVATGKLTAVTGPDGRKTKYSYNDRQQLTTTVYPDGLRSTREYDERGRLTAETSRTGETTRYSYDNPQSELPSGIHDATGSSKTMRWNRYGQMVAFTDCSGYETKYEYDRFGQMTAVHREEGQSIYRSYNRRGQLTAVRDSQGRETRYDYNDAGDLITVTGPDGNRTETQYDGWGKALSTTQGGLTRRMEYDAAGRVTQLTNENGSHSAFTWDTLDRLTQQTGFDGRVQRYGYDLTGKLTQSEDEDLVTHWHYDASDRLTHRTVNGLEAERWQYDEHGWLTELSHLSEEQRVAVYYGYDNKGRLIRERQTVSDPQTNELLWQHETLQGYSEQGLANRFKPDNLPPVEWLTYGSGYLAGMKLGDMPLLEYTRDRLHREVLRRFGSDTLPESYELTTTYTPGGQLHGQHLTLPQLNREYGYDEGGRLVRISGPQQTREYRYSDTGRLTSVHTTSTTLDITLPYATDPAGNRLPDPEFYPDSASTVWADNRITEDMQYLYRYDKYGRLTEKTDRIPEGGVIRMNDERTHRYEYDNQHRLVHYVRTQHGETQAEGRYLYDPLGRRVGKRVWKRERVHWSDTRMELSRRPYVTWYGWEGDRLTTIQTGQSRVQTLYAPGSFTPLVRIETDAAEQAKAQHRSLAEKLSQEGSEDGQAVQLPAALTAMLDRLEGELRRNAVSEESRAWLAGCGLTPEQMAEQLEPEYTPQRKIHLYHCDQRGLPLALVTPDNTVAWRGEYDEWGNLSGEENPEHLELVIRLPGQQYDEESGLYYNRHRYYNPGQGRYITQDPIGLKGGWNLYQYPLNPVTGTDPLGLKVTFKGDEEQQKAMKEAYESVRKTKHGQEMIEKMELSDHDYIFRGPRKGMEHTCYDPSEYTFYIEIDSDHAACQYQGKGKACKLTPTPLSVVIAHEMGHAMGENDDGPGHMNNVKKHENPVRKEMGIPPRMKY

Signal peptides

Signal peptides and corresponding cleavage sites are predicted using SignalP 5.0 software.

Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).

Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).

Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).

Prediction	Probability	Cleavage site	Signal peptide sequence
Other	0.3947	-	-

Protein sequence: 1406 a.a.

						>T6CP011698 NC_011205:1229589-1233806 [Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853] [PAAR]
MSGKPAARQGDMTQVGGPIVQGSAGVLIGAPTGVACSVCPTGEASPKYGNPVNPLLGAKVLPGETDIALPGPLPFVLSRA
YSSYRTKTPAPVGLCGPGWKLPSDLWLQLRGDGLILNDNGGRSVHFEPLAPGEIQYSRSESFWLARGGAASQHNSHPLSV
MWGMLPEAVRLCPHIYLATNSPQGPWWVLGWAERVPGADEALPAPLPPYRVLTGVVDGYGRRLTYHRDGAYGGAVTAVTD
STGRRYRLVLTTQAQRAAQAASASSSSLSPAPSSFPSFSSPPSPRSPSSWSETLPVTACGEDSGIRLSAVWLVEDPACPD
ALPSQPLVRYGYTARGELEAVYDRSGAEVRRFEYDAGQPGRMTAHRYAGRPASRYRYDDAGRVTEQVNPEGLGYAFAYEK
NKITVTDSLGRREVLHTEGEGGLKRVVMKASADGSVTRSRYDASGRPEWQTDATGRKTTYSPDVATGKLTAVTGPDGRKT
KYSYNDRQQLTTTVYPDGLRSTREYDERGRLTAETSRTGETTRYSYDNPQSELPSGIHDATGSSKTMRWNRYGQMVAFTD
CSGYETKYEYDRFGQMTAVHREEGQSIYRSYNRRGQLTAVRDSQGRETRYDYNDAGDLITVTGPDGNRTETQYDGWGKAL
STTQGGLTRRMEYDAAGRVTQLTNENGSHSAFTWDTLDRLTQQTGFDGRVQRYGYDLTGKLTQSEDEDLVTHWHYDASDR
LTHRTVNGLEAERWQYDEHGWLTELSHLSEEQRVAVYYGYDNKGRLIRERQTVSDPQTNELLWQHETLQGYSEQGLANRF
KPDNLPPVEWLTYGSGYLAGMKLGDMPLLEYTRDRLHREVLRRFGSDTLPESYELTTTYTPGGQLHGQHLTLPQLNREYG
YDEGGRLVRISGPQQTREYRYSDTGRLTSVHTTSTTLDITLPYATDPAGNRLPDPEFYPDSASTVWADNRITEDMQYLYR
YDKYGRLTEKTDRIPEGGVIRMNDERTHRYEYDNQHRLVHYVRTQHGETQAEGRYLYDPLGRRVGKRVWKRERVHWSDTR
MELSRRPYVTWYGWEGDRLTTIQTGQSRVQTLYAPGSFTPLVRIETDAAEQAKAQHRSLAEKLSQEGSEDGQAVQLPAAL
TAMLDRLEGELRRNAVSEESRAWLAGCGLTPEQMAEQLEPEYTPQRKIHLYHCDQRGLPLALVTPDNTVAWRGEYDEWGN
LSGEENPEHLELVIRLPGQQYDEESGLYYNRHRYYNPGQGRYITQDPIGLKGGWNLYQYPLNPVTGTDPLGLKVTFKGDE
EQQKAMKEAYESVRKTKHGQEMIEKMELSDHDYIFRGPRKGMEHTCYDPSEYTFYIEIDSDHAACQYQGKGKACKLTPTP
LSVVIAHEMGHAMGENDDGPGHMNNVKKHENPVRKEMGIPPRMKY*					

Nucleotide sequence: 4218 bp

						>T6CP011698 NC_011205:1229589-1233806 [Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853] [PAAR]
ATGAGCGGAAAACCAGCGGCGCGTCAGGGCGACATGACCCAGGTGGGCGGCCCGATAGTTCAGGGTTCAGCGGGGGTACT
GATAGGCGCACCGACGGGGGTGGCGTGCTCGGTGTGCCCAACCGGAGAGGCCAGTCCGAAGTACGGCAATCCGGTGAACC
CGCTGCTGGGGGCGAAGGTCCTGCCCGGCGAGACCGATATTGCGCTGCCCGGCCCGCTGCCGTTCGTGCTTTCCCGCGCC
TACAGCAGTTACCGGACGAAGACGCCCGCGCCGGTGGGGCTGTGCGGGCCGGGCTGGAAGCTGCCGTCAGACCTGTGGTT
ACAGCTGCGCGGCGACGGGCTGATACTGAACGATAACGGGGGCAGGAGCGTGCATTTTGAGCCTCTGGCGCCGGGGGAGA
TACAGTACAGCCGCAGCGAGTCATTCTGGCTGGCGCGGGGCGGGGCGGCATCGCAGCACAACAGCCACCCGCTGTCGGTC
ATGTGGGGCATGCTGCCGGAGGCGGTGCGGCTGTGCCCGCATATTTACCTGGCGACGAACAGCCCGCAGGGGCCGTGGTG
GGTGCTGGGATGGGCTGAACGGGTGCCGGGGGCGGATGAGGCGCTGCCCGCGCCGCTGCCGCCGTACCGGGTGCTGACGG
GGGTGGTGGACGGTTATGGCCGCCGTCTGACGTACCATCGCGACGGTGCATACGGCGGCGCGGTGACGGCGGTGACGGAC
AGCACCGGGCGGCGCTACCGGCTGGTGCTGACCACGCAGGCGCAGCGCGCGGCGCAGGCGGCGTCAGCGTCTTCTTCGTC
ATTATCTCCCGCCCCGTCGTCGTTCCCTTCATTTTCTTCCCCACCCTCTCCCCGCTCACCGTCCTCCTGGTCGGAGACGC
TGCCTGTAACCGCCTGCGGTGAGGACAGCGGCATCAGGCTGTCGGCGGTGTGGCTGGTGGAAGACCCGGCCTGTCCGGAT
GCGCTGCCGTCGCAGCCGCTGGTGCGTTACGGGTACACGGCGCGCGGTGAGCTGGAGGCGGTGTATGACCGCAGCGGTGC
GGAGGTAAGGCGCTTTGAGTATGACGCCGGGCAGCCGGGGAGGATGACGGCGCACCGTTACGCGGGAAGACCGGCGAGCC
GCTACCGGTATGATGACGCGGGGCGGGTGACGGAGCAGGTCAACCCGGAAGGGCTGGGTTATGCGTTCGCGTATGAGAAG
AACAAAATAACGGTAACGGACAGCCTGGGGCGGCGTGAAGTGCTGCACACGGAAGGCGAGGGTGGCCTGAAACGGGTGGT
GATGAAGGCGTCAGCCGACGGGAGCGTGACGCGCAGTAGATATGATGCGTCGGGAAGGCCAGAGTGGCAGACGGATGCGA
CGGGGAGGAAGACGACATACAGCCCGGACGTGGCGACAGGGAAGCTGACGGCGGTGACGGGGCCGGACGGGAGAAAGACG
AAGTACAGTTATAACGATCGGCAGCAACTGACGACGACGGTGTACCCGGACGGGCTGCGAAGCACGCGGGAGTATGATGA
GCGTGGCAGGCTGACGGCGGAGACATCGCGTACCGGTGAGACGACGCGGTACAGCTATGATAATCCGCAGAGTGAATTAC
CGTCCGGGATACATGACGCCACCGGCAGCAGTAAGACGATGCGCTGGAACCGCTACGGGCAGATGGTGGCGTTCACGGAC
TGTTCGGGGTATGAGACGAAGTATGAATATGACCGGTTCGGCCAGATGACGGCGGTACACCGGGAGGAAGGGCAGAGCAT
CTACCGCAGCTATAACCGCCGGGGACAGTTAACTGCCGTCAGGGACAGCCAGGGCCGTGAAACCCGCTACGATTATAACG
ATGCAGGCGACCTTATCACTGTGACCGGCCCGGACGGAAACCGCACTGAAACGCAGTACGACGGGTGGGGCAAGGCGCTC
AGTACCACACAGGGCGGGCTGACGCGGCGGATGGAATATGATGCTGCTGGCCGTGTGACGCAACTGACCAACGAGAACGG
CAGCCACAGCGCATTTACCTGGGATACGCTGGACCGCCTGACACAACAGACGGGCTTTGACGGACGGGTGCAGCGGTACG
GTTACGACCTGACGGGAAAACTCACACAGAGTGAAGATGAGGACCTGGTCACGCACTGGCACTACGATGCGTCAGACCGG
CTGACGCACCGTACCGTCAACGGCCTGGAGGCCGAACGCTGGCAGTATGACGAACACGGGTGGCTGACAGAGCTGAGTCA
CCTCAGCGAAGAGCAGCGTGTGGCGGTGTATTACGGCTACGATAATAAAGGCCGCCTTATCCGCGAACGCCAGACGGTGA
GTGACCCGCAGACGAATGAACTGTTATGGCAGCATGAGACACTACAGGGGTACAGTGAGCAGGGGCTGGCAAACCGGTTT
AAGCCGGATAACCTGCCGCCGGTGGAGTGGCTGACGTACGGGAGTGGTTATCTGGCGGGAATGAAGCTGGGGGATATGCC
GCTGCTGGAATACACGCGTGACAGGCTGCACCGTGAGGTGTTGCGGCGGTTCGGTTCAGACACCCTCCCGGAGAGTTATG
AACTGACGACCACATACACACCGGGCGGTCAGCTTCATGGTCAGCATCTGACACTGCCGCAGCTAAACCGGGAGTACGGT
TACGATGAGGGCGGCAGGCTGGTACGCATCAGCGGGCCGCAGCAGACGAGGGAATACCGCTACAGTGATACAGGACGCTT
AACTAGTGTCCATACCACCAGTACCACTCTGGACATCACCCTTCCGTATGCCACGGACCCGGCGGGGAACCGGCTGCCGG
ACCCGGAGTTTTACCCCGACAGCGCCAGTACGGTATGGGCGGATAACCGCATCACGGAAGATATGCAGTACCTGTACCGC
TACGACAAATACGGCAGGCTGACGGAGAAAACGGACCGCATCCCGGAAGGGGGGGTGATACGGATGAACGACGAACGTAC
ACACCGGTACGAATACGATAACCAGCACCGGCTGGTACATTATGTGCGCACACAGCACGGAGAAACGCAGGCGGAAGGGC
GGTATCTCTATGACCCGCTGGGCCGCCGTGTGGGTAAACGGGTATGGAAGCGGGAACGGGTTCACTGGAGCGACACGAGG
ATGGAGCTGTCGCGCAGGCCGTATGTGACGTGGTACGGCTGGGAGGGTGACAGGCTGACGACCATCCAGACCGGACAGAG
CCGCGTCCAGACGTTATATGCGCCGGGGAGTTTCACGCCGCTGGTGCGCATCGAAACAGATGCGGCTGAACAGGCGAAGG
CACAGCACCGCAGCCTGGCGGAGAAGCTGTCACAGGAGGGAAGTGAGGACGGCCAGGCGGTACAGCTTCCGGCGGCGCTG
ACGGCGATGCTGGACAGACTGGAGGGCGAACTGAGGCGTAACGCGGTGAGTGAGGAGAGCCGGGCATGGCTGGCGGGATG
CGGGCTGACGCCGGAGCAGATGGCGGAACAACTGGAGCCGGAGTACACACCCCAAAGGAAAATCCATCTTTACCACTGCG
ACCAGCGTGGACTGCCGCTGGCGCTGGTTACCCCGGACAACACGGTGGCGTGGCGCGGGGAGTATGATGAATGGGGAAAC
CTGTCGGGTGAGGAAAATCCTGAGCACCTGGAGCTGGTGATACGGCTGCCGGGGCAGCAATATGATGAGGAATCGGGGCT
GTATTATAACCGGCACCGTTATTATAATCCGGGACAGGGGAGGTATATTACACAGGATCCGATAGGGCTGAAAGGGGGAT
GGAACCTGTACCAGTATCCGCTGAACCCTGTCACAGGTACAGATCCATTGGGATTAAAGGTGACTTTTAAGGGTGACGAA
GAACAGCAAAAAGCTATGAAAGAGGCATACGAATCTGTAAGGAAGACAAAACATGGTCAGGAAATGATAGAAAAAATGGA
GTTATCTGATCATGATTATATATTTAGAGGACCGAGGAAAGGTATGGAACATACATGCTACGATCCCTCCGAATATACTT
TCTATATTGAAATAGATTCTGACCATGCCGCATGCCAATATCAAGGAAAAGGTAAAGCATGCAAACTGACACCTACGCCA
TTAAGTGTAGTTATCGCCCACGAAATGGGGCATGCAATGGGTGAAAATGACGACGGACCAGGACATATGAATAATGTCAA
AAAACATGAGAACCCTGTCCGCAAAGAAATGGGAATCCCACCAAGGATGAAATACTGA					