Detailed information of component protein


Summary

Component ID T6CP003071
Component protein type TssM
T6SS ID (Type) T6SS00302 insolico (Type i1)
Strain Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853
Replicon chromosome
Sequence Protein sequence (1154 a.a.); Nucleotide sequence (3462 bp)
Reference
insolico Bioinformatics investigation has been performed on this T6SS
External database links

Locus tag (Gene) SED_RS06250
Coordinate (Strand) 1208040..1211501 (-)
NCBI ID 447059848
RefSeq NC_011205
Uniprot ID -
KEGG ID -
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
IcmF-related PF06761.14 2.4e-66 485..797
IcmF-related_N PF14331.8 2.2e-59 185..429
IcmF_C PF06744.14 1.7e-19 1027..1132
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Inside 1-6 MPRFKV
Transmembrane helix 7-25 SAAWLLALAWILLLVWFWW
Outside 26-44 KGPSWTLYEQRWLAPLANR
Transmembrane helix 45-64 WLATAAWGLIALTWLTVRVM
Inside 65-428 KRLQLLEKQQRQQRDEAQDPLSVELNTQQRYLDHWLLRLQRHLDSRRYLWQLPWYMVTGPAGSGKTTLLREGYPSDIIYAPEALRGVEQRRYVIPHVGKQAVIFDADGLLFEQQDADILHRRLWTHMLDWLAQKRARQPLNGLILTLDLPDLLTADKPRREHLLQILRGRLQDIRQHLHCQLPVYVVLTRLDLLHGFAALFQSLDRNDRDAILGVTFTRHAHENDDWRTELNAFWQTWGEQLNNVLPERMLAPGSRSSLFSFVRQIQGGREPLIALLNGLLDGENMDVMLRGVYLTSSLQRGQIDDIFMQSAARQFRLGSSPLTAWPLVDTLPYFTRNLFPQTLLAEPNLASESRVWLMQSRRR
Transmembrane helix 429-451 LSVFSATGGIAALLLIIGWHHYY
Outside 452-1153 NNNWRSGITVLEQAKAFMSVPPPQGMDDYGNLQLPLLNPVRDATLAYGDWGDRSRLADMGLYQGRRVGPYVEQTYLQLLEQRYLPALFNGLVKEMNAAPAESEEKLAVLRVIRMLEDKSGRSDEVVKQYMAKRWSDKFHGQRDIQAQLMSHLDYALKHTDWHAERQAGDGDAISRWTPYDNPVVAAQKELSKLPVYQRVYQSLKTRAMGVLPADLNLRDQVGATFDQVFTSGDDNKLIVPQFLTRYGLQSYFVKQRDALIELTAMDSWVLNLTRSVKYSDADRAEIQRQLTEQYLSDYTATWRAGMDNLNVRNYESIAQLTGALEQIISGDQPLQRALTALRDNTQPAVLSEKLDDKALQEAMAEPDYQLLTRLGHEFAPENSTLAVQKDKENTLQAVYQQLTELHRYLLAIQNAPVPGKSALKAVQLRLDQNSSDPIFATRQMAKTLPAPLNRWVGKLADQAWHVVMVEAVHYMEVDWRDNVVKPFNEQLADNYPFNPRSQSDASLDAFERFFKPNGVLDTFYQQNLRLFMENDLSLEDGDNNVIIREDVREQLDTAQEIREAFFSRQNGLGAQFAVETVSLSGNKRRSVLNLDGQLVDYSQGRNYTAHLVWPNNMREGNESKLTLIGVSGGAPRSISFSGPWAQFRLFGAGQLTGVQEGTFSVRFNVDGGAMVYRVHTDTEDNPFTGGLFSQFRLPDTLY


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9972 - -


  Protein sequence: 1154 a.a.    

>T6CP003071 NC_011205:c1211501-1208040 [Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853] [TssM]
MPRFKVSAAWLLALAWILLLVWFWWKGPSWTLYEQRWLAPLANRWLATAAWGLIALTWLTVRVMKRLQLLEKQQRQQRDE
AQDPLSVELNTQQRYLDHWLLRLQRHLDSRRYLWQLPWYMVTGPAGSGKTTLLREGYPSDIIYAPEALRGVEQRRYVIPH
VGKQAVIFDADGLLFEQQDADILHRRLWTHMLDWLAQKRARQPLNGLILTLDLPDLLTADKPRREHLLQILRGRLQDIRQ
HLHCQLPVYVVLTRLDLLHGFAALFQSLDRNDRDAILGVTFTRHAHENDDWRTELNAFWQTWGEQLNNVLPERMLAPGSR
SSLFSFVRQIQGGREPLIALLNGLLDGENMDVMLRGVYLTSSLQRGQIDDIFMQSAARQFRLGSSPLTAWPLVDTLPYFT
RNLFPQTLLAEPNLASESRVWLMQSRRRLSVFSATGGIAALLLIIGWHHYYNNNWRSGITVLEQAKAFMSVPPPQGMDDY
GNLQLPLLNPVRDATLAYGDWGDRSRLADMGLYQGRRVGPYVEQTYLQLLEQRYLPALFNGLVKEMNAAPAESEEKLAVL
RVIRMLEDKSGRSDEVVKQYMAKRWSDKFHGQRDIQAQLMSHLDYALKHTDWHAERQAGDGDAISRWTPYDNPVVAAQKE
LSKLPVYQRVYQSLKTRAMGVLPADLNLRDQVGATFDQVFTSGDDNKLIVPQFLTRYGLQSYFVKQRDALIELTAMDSWV
LNLTRSVKYSDADRAEIQRQLTEQYLSDYTATWRAGMDNLNVRNYESIAQLTGALEQIISGDQPLQRALTALRDNTQPAV
LSEKLDDKALQEAMAEPDYQLLTRLGHEFAPENSTLAVQKDKENTLQAVYQQLTELHRYLLAIQNAPVPGKSALKAVQLR
LDQNSSDPIFATRQMAKTLPAPLNRWVGKLADQAWHVVMVEAVHYMEVDWRDNVVKPFNEQLADNYPFNPRSQSDASLDA
FERFFKPNGVLDTFYQQNLRLFMENDLSLEDGDNNVIIREDVREQLDTAQEIREAFFSRQNGLGAQFAVETVSLSGNKRR
SVLNLDGQLVDYSQGRNYTAHLVWPNNMREGNESKLTLIGVSGGAPRSISFSGPWAQFRLFGAGQLTGVQEGTFSVRFNV
DGGAMVYRVHTDTEDNPFTGGLFSQFRLPDTLY*

  Nucleotide sequence: 3462 bp    

>T6CP003071 NC_011205:c1211501-1208040 [Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853] [TssM]
ATGCCCCGGTTTAAGGTTTCTGCCGCCTGGCTGCTGGCGCTGGCGTGGATTTTGCTGCTGGTATGGTTCTGGTGGAAAGG
TCCGTCATGGACGCTCTACGAGCAGCGCTGGCTGGCCCCGCTGGCGAACCGCTGGCTGGCCACCGCCGCCTGGGGGTTGA
TTGCGCTGACGTGGCTGACCGTCCGGGTCATGAAGCGCCTGCAACTGCTGGAAAAACAGCAGCGCCAGCAACGGGACGAG
GCGCAGGATCCGCTCAGCGTGGAACTGAACACCCAGCAACGCTATCTCGATCACTGGTTACTGCGTCTGCAACGCCATCT
CGACAGCCGCCGCTATCTGTGGCAGCTACCGTGGTATATGGTCACTGGCCCGGCGGGAAGCGGTAAAACCACGCTGCTGC
GCGAAGGGTATCCGTCCGACATTATTTATGCCCCGGAGGCGCTGCGGGGCGTGGAGCAGCGCCGGTATGTTATCCCGCAT
GTGGGAAAACAGGCGGTGATTTTTGACGCTGACGGCCTCCTCTTTGAGCAACAGGATGCGGATATACTGCATCGCCGCCT
GTGGACCCATATGCTGGACTGGCTGGCGCAAAAACGCGCCCGGCAGCCGCTGAACGGCCTGATACTGACGCTGGATCTGC
CCGATCTTCTGACCGCCGACAAGCCACGCCGTGAGCACCTGTTGCAGATCCTGCGCGGACGTTTGCAGGATATACGCCAG
CATCTTCACTGCCAGCTCCCCGTCTATGTGGTGCTGACCCGGCTGGATCTACTGCACGGTTTCGCCGCCCTGTTTCAGTC
ACTGGACCGCAACGATCGCGACGCCATTCTTGGCGTCACCTTTACCCGTCATGCCCATGAAAATGACGACTGGCGTACAG
AACTGAATGCCTTCTGGCAGACATGGGGCGAACAGTTGAATAACGTCCTGCCGGAGCGGATGTTAGCCCCCGGCTCCCGC
AGTTCCCTGTTCAGCTTTGTCCGCCAGATCCAGGGGGGCCGCGAGCCGCTGATCGCCCTGCTGAACGGGCTGCTGGACGG
GGAAAATATGGATGTGATGCTGCGCGGCGTGTACCTCACCTCCTCCCTGCAACGCGGCCAGATAGACGATATTTTTATGC
AGTCCGCCGCCCGTCAGTTCCGGCTGGGCAGCAGTCCGCTGACCGCCTGGCCGCTGGTGGACACGTTACCGTATTTCACC
CGTAATCTGTTTCCGCAGACCTTACTGGCTGAGCCGAACCTCGCCAGTGAAAGCCGCGTCTGGCTGATGCAGTCCCGCCG
CCGGTTGTCCGTGTTTTCCGCCACTGGCGGCATCGCCGCCCTGCTGCTGATTATCGGCTGGCATCACTATTACAATAACA
ACTGGCGTTCCGGCATCACCGTACTGGAGCAGGCCAAAGCTTTTATGTCGGTTCCGCCACCGCAGGGTATGGACGATTAT
GGCAACCTGCAACTACCGTTACTTAACCCGGTGCGTGACGCCACGCTGGCCTACGGCGACTGGGGCGATCGCAGTCGTCT
GGCCGATATGGGATTATATCAGGGCAGGCGTGTCGGCCCATATGTGGAGCAGACCTACCTGCAACTGCTGGAGCAGCGTT
ACCTGCCCGCCCTGTTTAACGGCCTGGTCAAAGAGATGAATGCCGCGCCTGCGGAGAGCGAGGAGAAGCTCGCGGTATTG
CGCGTTATCAGAATGCTGGAAGATAAAAGCGGACGCAGCGACGAGGTGGTGAAGCAGTATATGGCGAAACGCTGGAGCGA
TAAATTTCACGGCCAGCGCGATATTCAGGCACAGCTAATGTCTCATCTGGACTACGCGCTGAAACACACCGACTGGCACG
CGGAGCGTCAGGCAGGCGACGGCGACGCCATCAGCCGCTGGACGCCGTATGACAATCCGGTCGTGGCGGCGCAGAAAGAG
CTCAGCAAACTGCCCGTCTACCAGCGCGTTTACCAGAGTCTGAAAACGCGGGCGATGGGCGTGCTGCCCGCTGATCTGAA
CCTGCGTGACCAGGTGGGCGCCACGTTTGATCAGGTCTTTACCTCCGGGGATGATAATAAGCTCATTGTTCCGCAGTTCC
TCACCCGTTACGGTCTGCAAAGTTATTTTGTCAAACAGCGCGACGCGCTGATCGAACTGACGGCGATGGATTCCTGGGTG
CTGAACCTGACCCGCAGCGTGAAATACAGCGACGCCGACCGGGCGGAAATCCAGCGCCAGCTCACTGAACAGTATCTCAG
CGACTACACCGCCACCTGGCGCGCCGGAATGGACAACCTTAACGTGCGCAATTACGAATCCATTGCGCAACTGACCGGGG
CGCTGGAGCAGATCATCAGCGGCGATCAGCCGCTCCAGCGGGCGCTGACGGCACTGCGCGACAACACGCAGCCTGCCGTT
CTCTCTGAAAAACTGGATGACAAGGCGCTTCAGGAGGCGATGGCGGAGCCGGATTACCAGTTGCTGACCCGCCTGGGGCA
TGAATTTGCCCCGGAAAACAGCACGCTGGCGGTACAGAAAGACAAAGAAAACACTCTCCAGGCGGTCTATCAGCAACTGA
CGGAGCTGCACCGTTACCTGCTGGCTATTCAGAACGCGCCGGTGCCGGGAAAATCAGCGCTGAAAGCGGTGCAGCTACGG
CTGGATCAGAACAGCAGCGATCCTATTTTCGCCACCCGCCAGATGGCGAAAACCCTGCCTGCCCCGCTCAACCGCTGGGT
GGGCAAGCTGGCGGATCAGGCCTGGCATGTGGTGATGGTGGAGGCAGTTCACTATATGGAAGTGGACTGGCGCGACAACG
TGGTCAAACCCTTTAATGAACAACTCGCCGACAATTATCCGTTTAACCCACGCTCACAGTCAGATGCGTCGCTGGATGCG
TTTGAACGCTTCTTTAAACCGAATGGCGTACTGGATACCTTTTATCAGCAGAACCTGCGTCTGTTTATGGAAAACGATCT
GAGTCTGGAGGACGGGGATAACAACGTGATTATTCGTGAGGATGTCCGGGAGCAACTGGATACCGCACAGGAAATCCGCG
AGGCGTTTTTCAGCAGACAGAACGGCCTGGGCGCGCAGTTTGCCGTGGAAACTGTGTCGCTTTCCGGCAACAAACGGCGC
AGCGTGCTGAATCTGGACGGGCAGTTAGTGGACTACAGCCAGGGCCGCAATTACACCGCCCATCTGGTCTGGCCGAACAA
CATGCGTGAAGGCAATGAAAGTAAGCTGACGCTGATAGGCGTCAGTGGCGGCGCGCCGCGCAGCATCAGTTTCAGCGGGC
CGTGGGCGCAGTTCAGGCTGTTCGGCGCCGGGCAACTTACCGGCGTTCAGGAGGGGACATTCAGCGTGCGCTTTAACGTG
GACGGCGGAGCGATGGTGTACCGGGTACATACCGATACGGAAGATAACCCCTTCACCGGCGGGCTGTTCAGTCAGTTCCG
GCTGCCGGATACCCTGTACTGA