SecReT6, T6SS database

Detailed information of component protein

Summary

Component ID	T6CP003081
Component protein type	TssI
T6SS ID (Type)	T6SS00302 (Type i1)
Strain	Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853
Replicon	chromosome
Sequence	Protein sequence (705 a.a.); Nucleotide sequence (2115 bp)
Reference	[1] Blondel CJ, Jiménez JC, Contreras I, et al. Comparative genomic analysis uncovers 3 novel loci encoding type six secretion systems differentially distributed in Salmonella serotypes. BMC Genomics. 2009 Aug 4;10:354. doi: 10.1186/1471-2164-10-354. PMID: 19653904 [2] Pezoa D, Blondel CJ, Silva CA, et al. Only one of the two type VI secretion systems encoded in the Salmonella enterica serotype Dublin genome is involved in colonization of the avian and murine hosts. Vet Res. 2014 Jan 9;45:2. doi: 10.1186/1297-9716-45-2. PMID: 24405577

Bioinformatics investigation has been performed on this T6SS

External database links

Locus tag (Gene)	SED_RS06330
Coordinate (Strand)	1227373..1229487 (+)
NCBI ID	446025603
RefSeq	NC_011205
Uniprot ID	-
KEGG ID	-
PDB ID	-

Pfam domain hit(s)

Domain	Pfam ID	E-value	Aligned region
Phage_GPD	PF05954.13	1.3e-73	29..327
Phage_base_V	PF04717.14	1.6e-14	384..450

Transmembrane helices

Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction	Region	Sequence
Outside	1-704	MSTGLRFTLEVDGLPSDALVVESFHLSQSLSTLFSLDISLVSQQLHNIEFAQVLEKPAHLKIWQGTEIQRRVNGIVTWFEQGENDGHQMLYSMKVRPPVWRAALRQNSRIFQNEDIKSILGTILQENGVTDWSPLFSEAHPAREFCVQYSETDYDFLARMAAEEGIFFYEEHAQTSDDQSLVLCDTVRFLPEAFEIPWNPNTRTEVSTPCVSQFRHSAQIRPSSVIGKDYTFKRPGWAGRFEHQGEHQDYQRTQYEVFDYPGRFKDGHGQNFARWQMEGWRNNAEVAQGKSRSPAIWPGRRIQLTEHPQASLNREWQVVSSDLHGSQPQAAAGRSGSGTTLDNHFTVIPADRTWRPRPLPKPSVDGPQSAVVTGPEGEEIFCDEHGRVRVKFNWDRYNPANQDSSCWIRVVQAWAGPGFGNLAIPRVGQEVIVDFLNGDPDQPIIMGRTYHQENRSPGSLPGTKTQMTIRSKTYKGSGFNELMFDDATGKERVYIHAQKNMNTEVLRNRTTDVTNNHAETIGNNQVIAVTNNQIQTIGVNQVEKVGSNQVIKVGANQVETVGIVRALNVGLAYQTTVGGIMNTSVALMQSSEVGIFKSLNVGMKYNVNVGRNASVNVGNSKTESTGKTAVYSAGEHLELVCGEARLVLTSDGGIFLNGKHIELQGVDSLNGDSKLISWNCGVSKKPPEASEQQDDPDPSDLIMY

Signal peptides

Signal peptides and corresponding cleavage sites are predicted using SignalP 5.0 software.

Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).

Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).

Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).

Prediction	Probability	Cleavage site	Signal peptide sequence
Other	0.9955	-	-

Protein sequence: 705 a.a.

						>T6CP003081 NC_011205:1227373-1229487 [Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853] [TssI]
MSTGLRFTLEVDGLPSDALVVESFHLSQSLSTLFSLDISLVSQQLHNIEFAQVLEKPAHLKIWQGTEIQRRVNGIVTWFE
QGENDGHQMLYSMKVRPPVWRAALRQNSRIFQNEDIKSILGTILQENGVTDWSPLFSEAHPAREFCVQYSETDYDFLARM
AAEEGIFFYEEHAQTSDDQSLVLCDTVRFLPEAFEIPWNPNTRTEVSTPCVSQFRHSAQIRPSSVIGKDYTFKRPGWAGR
FEHQGEHQDYQRTQYEVFDYPGRFKDGHGQNFARWQMEGWRNNAEVAQGKSRSPAIWPGRRIQLTEHPQASLNREWQVVS
SDLHGSQPQAAAGRSGSGTTLDNHFTVIPADRTWRPRPLPKPSVDGPQSAVVTGPEGEEIFCDEHGRVRVKFNWDRYNPA
NQDSSCWIRVVQAWAGPGFGNLAIPRVGQEVIVDFLNGDPDQPIIMGRTYHQENRSPGSLPGTKTQMTIRSKTYKGSGFN
ELMFDDATGKERVYIHAQKNMNTEVLRNRTTDVTNNHAETIGNNQVIAVTNNQIQTIGVNQVEKVGSNQVIKVGANQVET
VGIVRALNVGLAYQTTVGGIMNTSVALMQSSEVGIFKSLNVGMKYNVNVGRNASVNVGNSKTESTGKTAVYSAGEHLELV
CGEARLVLTSDGGIFLNGKHIELQGVDSLNGDSKLISWNCGVSKKPPEASEQQDDPDPSDLIMY*					

Nucleotide sequence: 2115 bp

						>T6CP003081 NC_011205:1227373-1229487 [Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853] [TssI]
ATGTCAACAGGATTACGTTTCACACTGGAGGTGGACGGCCTGCCATCGGATGCGCTGGTCGTGGAGTCCTTTCACCTGAG
CCAGTCCCTTTCCACGTTATTTTCCCTCGATATCTCGCTGGTCAGTCAGCAACTTCACAACATTGAGTTTGCCCAGGTAC
TGGAAAAACCGGCGCACCTGAAAATCTGGCAGGGCACGGAGATACAGCGCCGGGTGAACGGCATAGTGACCTGGTTTGAG
CAGGGGGAAAACGACGGACACCAGATGCTGTACAGCATGAAAGTTCGTCCGCCGGTGTGGCGCGCCGCGCTGCGGCAGAA
CTCGCGTATTTTCCAGAATGAAGACATAAAAAGCATTCTCGGGACGATACTGCAGGAAAACGGCGTGACGGACTGGAGCC
CGCTGTTCAGTGAGGCGCATCCGGCGCGGGAGTTCTGCGTGCAGTACAGCGAAACGGATTACGACTTTCTGGCGCGGATG
GCGGCGGAGGAAGGTATTTTCTTTTACGAGGAACATGCGCAGACCAGCGACGACCAGAGCCTGGTGCTGTGCGACACGGT
ACGTTTTCTGCCGGAAGCCTTTGAAATCCCCTGGAACCCGAACACCCGTACCGAGGTGAGCACGCCGTGCGTCAGCCAGT
TCCGCCACAGCGCGCAAATCCGCCCCTCTTCCGTCATCGGCAAGGACTACACCTTCAAACGCCCCGGCTGGGCGGGCCGC
TTTGAGCACCAGGGCGAACATCAGGATTACCAGCGCACGCAGTATGAGGTCTTTGATTATCCGGGGCGCTTCAAGGACGG
CCACGGTCAGAACTTCGCCCGCTGGCAGATGGAAGGCTGGCGTAATAATGCCGAAGTGGCGCAGGGGAAAAGCCGTTCGC
CGGCGATATGGCCGGGACGGCGTATTCAGCTGACGGAACACCCGCAGGCGAGCCTGAACCGGGAATGGCAGGTGGTGAGC
AGCGATTTACACGGCAGCCAGCCGCAGGCGGCGGCGGGGCGCTCAGGTTCAGGGACAACGCTGGACAATCATTTTACGGT
CATCCCGGCAGACAGAACATGGCGGCCACGCCCGCTGCCCAAACCATCAGTGGACGGCCCGCAGTCGGCGGTGGTCACCG
GCCCGGAAGGGGAAGAAATCTTCTGCGACGAACATGGCCGTGTACGGGTGAAATTTAACTGGGACCGGTATAACCCGGCG
AACCAGGACAGCTCGTGCTGGATACGGGTGGTACAGGCGTGGGCGGGGCCGGGGTTCGGCAACCTGGCGATACCGCGCGT
GGGGCAGGAAGTGATAGTGGACTTCCTCAACGGCGACCCGGACCAGCCCATCATCATGGGGCGCACCTACCACCAGGAAA
ACCGCTCACCGGGCAGCCTGCCGGGCACCAAAACGCAGATGACCATCCGCTCGAAAACCTATAAAGGCAGCGGGTTTAAC
GAACTCATGTTTGATGATGCGACAGGGAAGGAGCGCGTGTATATCCACGCGCAGAAGAATATGAATACCGAGGTGCTGCG
CAACCGCACCACCGATGTGACGAATAATCATGCTGAAACCATTGGTAATAACCAGGTGATCGCCGTTACCAATAACCAAA
TCCAGACCATCGGCGTCAACCAGGTGGAGAAGGTGGGCAGTAACCAGGTGATCAAGGTGGGTGCCAATCAGGTGGAAACG
GTGGGGATTGTCCGCGCCCTGAATGTGGGGCTGGCATACCAGACTACCGTGGGCGGCATCATGAATACCTCGGTGGCGCT
GATGCAGTCTTCTGAGGTCGGGATCTTCAAATCACTGAATGTGGGAATGAAATACAACGTCAATGTCGGGCGTAATGCCA
GCGTTAACGTGGGCAACAGTAAAACCGAAAGTACCGGTAAAACGGCGGTGTATTCCGCAGGCGAGCATCTGGAACTGGTG
TGTGGTGAAGCCCGTCTGGTGCTGACGAGCGACGGCGGTATTTTTCTGAACGGCAAACATATTGAGTTGCAGGGCGTGGA
CAGCTTAAACGGGGATTCAAAGCTGATCAGCTGGAACTGTGGGGTGAGCAAGAAGCCACCTGAAGCATCTGAACAGCAGG
ATGACCCCGATCCATCGGATCTGATCATGTACTGA					