Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS00013  |
| T6SS type | Type i1 |
| Strain | Pseudomonas putida KT2440 |
| Replicon (RefSeq) | chromosome (NC_002947) |
| Location | 2984253..3012550 |
| Function | anti-bacterial |
| Comment | The K1-T6SS is anti-bacterial and can secrete HCP1. |
| References | [1] Bernal P, Allsopp LP, Filloux A, Llamas MA. et al (2017) The Pseudomonas putida T6SS is a plant warden against phytopathogens.. ISME J. 11(4):972-987. [PudMed:28045455] [2] Boyer F et al (2009) Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 0.488888889. [PudMed:19284603] [3] Barret M et al (2011) Genomic analysis of the type VI secretion systems in Pseudomonas spp.: novel clusters and putative effectors uncovered. Microbiology. 157(Pt 6):1726-39. [PudMed:21474537] |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | FHA | PAAR | TagT | TssB | TssC | TssD | TssE | TssF | TssG | TssI | TssJ | TssK | TssL | TssM |
| Number | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| PP_RS13590 | 2980326..2980646 | - | 321 | WP_003250862.1 | NIPSNAP family protein | ||
| PP_RS13595 | 2980631..2982364 | - | 1734 | WP_010953528.1 | FAD-dependent oxidoreductase | ||
| PP_RS13600 | 2982369..2983178 | - | 810 | WP_010953529.1 | shikimate dehydrogenase | ||
| PP_RS13605 | 2983335..2984105 | + | 771 | WP_010953530.1 | IclR family transcriptional regulator | ||
| T6CP011402 | PAAR | PP_RS13610 | 2984256..2984513 | - | 258 | WP_003250871.1 | PAAR domain-containing protein |
| PP_RS13615 | 2984510..2985403 | - | 894 | WP_049588127.1 | hypothetical protein | ||
| PP_RS13620 | 2985408..2988398 | - | 2991 | WP_010953532.1 | hypothetical protein | ||
| PP_RS13625 | 2988391..2989314 | - | 924 | WP_049586296.1 | DUF4123 domain-containing protein | ||
| T6CP009574 | TssI | PP_RS13630 (tssI) | 2989311..2991479 | - | 2169 | WP_010953534.1 | type VI secretion system tip protein VgrG |
| T6CP009575 | TssD | PP_RS13635 | 2991554..2992069 | - | 516 | WP_010953535.1 | Hcp family type VI secretion system effector |
| T6CP009576 | TssL | PP_RS13640 (icmH) | 2992203..2993072 | - | 870 | WP_010953536.1 | type IVB secretion system protein IcmH/DotU |
| T6CP000090 | TssK | PP_RS13645 (tssK) | 2993074..2994411 | - | 1338 | WP_010953537.1 | type VI secretion system baseplate subunit TssK |
| T6CP000091 | TssJ | PP_RS13650 (tssJ) | 2994467..2995264 | - | 798 | WP_010953538.1 | type VI secretion system lipoprotein TssJ |
| T6CP011401 | FHA | PP_RS13655 | 2995261..2995830 | - | 570 | WP_010953539.1 | FHA domain-containing protein |
| T6CP000092 | TssG | PP_RS13660 (tssG) | 2995827..2996843 | - | 1017 | WP_010953540.1 | type VI secretion system baseplate subunit TssG |
| T6CP000093 | TssF | PP_RS13665 (tssF) | 2996807..2998573 | - | 1767 | WP_010953541.1 | type VI secretion system baseplate subunit TssF |
| T6CP009577 | TssE | PP_RS13670 (tssE) | 2998577..2998987 | - | 411 | WP_010953542.1 | type VI secretion system baseplate subunit TssE |
| T6CP000094 | TssC | PP_RS13675 (tssC) | 2998984..3000474 | - | 1491 | WP_010953543.1 | type VI secretion system contractile sheath large subunit |
| T6CP000095 | TssB | PP_RS13680 (tssB) | 3000492..3000995 | - | 504 | WP_010953544.1 | type VI secretion system contractile sheath small subunit |
| PP_RS13685 (tagO) | 3001322..3001972 | + | 651 | WP_172835029.1 | type VI secretion system-associated protein TagO | ||
| PP_RS13690 (tssA) | 3001960..3003423 | + | 1464 | WP_010953546.1 | type VI secretion system protein TssA | ||
| T6CP009580 | TssM | PP_RS13695 (tssM) | 3003420..3007040 | + | 3621 | WP_010953547.1 | type VI secretion system membrane subunit TssM |
| T6CP012425 | TagT | PP_RS13700 | 3007118..3008971 | - | 1854 | WP_028697022.1 | ABC transporter ATP-binding protein/permease |
| PP_RS28315 | 3008970..3009125 | + | 156 | WP_164721826.1 | hypothetical protein | ||
| PP_RS13705 | 3009274..3010765 | + | 1492 | pseudogene | peptidase | ||
| PP_RS13710 (bcsF) | 3010762..3010947 | + | 186 | WP_010953551.1 | cellulose biosynthesis protein BcsF | ||
| PP_RS13715 (bcsG) | 3010940..3012553 | + | 1614 | WP_010953552.1 | cellulose biosynthesis protein BcsG | ||
| PP_RS13720 | 3012550..3012768 | + | 219 | WP_010953553.1 | hypothetical protein | ||
| PP_RS13725 (yhjQ) | 3012765..3013472 | + | 708 | WP_010953554.1 | cellulose synthase operon protein YhjQ | ||
| PP_RS13730 (bcsA) | 3013469..3016078 | + | 2610 | WP_010953555.1 | UDP-forming cellulose synthase catalytic subunit |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
|---|