Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   EL076_RS06975 Genome accession   NZ_LR134275
Coordinates   1398817..1399461 (-) Length   214 a.a.
NCBI ID   WP_003094523.1    Uniprot ID   -
Organism   Streptococcus vestibularis strain NCTC12167     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1393817..1404461
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL076_RS06950 (NCTC12167_01369) - 1395914..1396912 (-) 999 WP_126429832.1 NAD(P)/FAD-dependent oxidoreductase -
  EL076_RS06955 (NCTC12167_01370) trmD 1396914..1397633 (-) 720 WP_126429834.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  EL076_RS06960 (NCTC12167_01371) rimM 1397623..1398141 (-) 519 WP_126429836.1 ribosome maturation factor RimM -
  EL076_RS06975 (NCTC12167_01374) vraR 1398817..1399461 (-) 645 WP_003094523.1 response regulator transcription factor Regulator
  EL076_RS06980 (NCTC12167_01375) - 1399451..1400461 (-) 1011 WP_048788123.1 sensor histidine kinase -
  EL076_RS06985 (NCTC12167_01376) liaF 1400458..1401156 (-) 699 WP_003096617.1 cell wall-active antibiotics response protein LiaF -
  EL076_RS10340 (NCTC12167_01377) - 1401310..1401759 (-) 450 WP_232009625.1 potassium channel family protein -
  EL076_RS06995 (NCTC12167_01378) stkP/pknB 1402213..1404081 (-) 1869 WP_126429838.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24007.33 Da        Isoelectric Point: 4.5762

>NTDB_id=999710 EL076_RS06975 WP_003094523.1 1398817..1399461(-) (vraR) [Streptococcus vestibularis strain NCTC12167]
MSNKINVILVDDHEMVRLGLKSFLNLQGDVEVVGEAGNGRDGIDLALELRPDVVVMDLVMPELDGVQATLELLKEWPEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSATEILNSIRKVYRGEEAIETEVDNKIKYHDSHPDLHDDLTARERDILALL
AKGYDNQTIANELFISLKTVKTHVSNILGKLNVDDRTQAVVYAFRHHLVSQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=999710 EL076_RS06975 WP_003094523.1 1398817..1399461(-) (vraR) [Streptococcus vestibularis strain NCTC12167]
ATGTCGAATAAGATTAATGTGATTTTGGTAGATGACCATGAAATGGTTCGTTTAGGCCTTAAGAGTTTCTTGAATCTCCA
AGGAGATGTAGAAGTGGTGGGAGAGGCAGGAAATGGTCGTGATGGTATCGATCTTGCCCTGGAGTTGCGTCCAGACGTTG
TTGTTATGGATCTTGTTATGCCTGAGTTAGATGGTGTTCAGGCGACTTTGGAATTGCTCAAAGAATGGCCTGAAGCTAAG
ATTTTAGTTTTGACCAGCTATTTGGACAATGAAAAAATTTATCCAGTCATAGAAGCTGGCGCCAAAGGCTATATGCTTAA
AACGAGCAGTGCAACAGAGATTCTAAATAGTATCCGAAAGGTTTACCGTGGAGAAGAAGCTATCGAAACTGAGGTGGACA
ATAAGATTAAATACCACGATAGTCACCCGGACTTACATGATGATTTGACCGCACGTGAACGTGATATCTTAGCCCTCTTA
GCTAAAGGCTATGACAATCAAACCATTGCTAACGAACTGTTTATTTCTTTAAAAACCGTCAAGACCCATGTGTCTAATAT
CCTTGGGAAATTAAATGTTGATGACCGTACTCAGGCTGTAGTTTATGCCTTTAGACATCATCTGGTTTCACAGGATGATG
AATAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-203)

Response regulator receiver domain (Response_reg)

(7-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

50.485

96.262

0.486
  degU Bacillus subtilis subsp. subtilis str. 168

35.909

100

0.369

Multiple sequence alignment