Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   R8635_RS10425 Genome accession   NZ_AP026924
Coordinates   1999680..2000006 (-) Length   108 a.a.
NCBI ID   WP_000738630.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700063     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1994680..2005006
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8635_RS10380 (PC0062_20270) rnpA 1994697..1995068 (-) 372 WP_000739246.1 ribonuclease P protein component -
  R8635_RS10385 - 1995085..1995216 (-) 132 WP_000768904.1 hypothetical protein -
  R8635_RS10390 (PC0062_20280) - 1995217..1996407 (-) 1191 WP_050245357.1 acetate kinase -
  R8635_RS10395 (PC0062_20290) comYH 1996458..1997411 (-) 954 WP_050233486.1 class I SAM-dependent methyltransferase Machinery gene
  R8635_RS10400 - 1997472..1998066 (-) 595 Protein_2030 class I SAM-dependent methyltransferase -
  R8635_RS10405 (PC0062_20320) comGG/cglG 1998203..1998616 (-) 414 WP_000265620.1 competence type IV pilus minor pilin ComGG Machinery gene
  R8635_RS10410 comGF/cglF 1998594..1999055 (-) 462 WP_000250540.1 competence type IV pilus minor pilin ComGF Machinery gene
  R8635_RS10415 (PC0062_20340) comGE/cglE 1999018..1999320 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  R8635_RS10420 (PC0062_20350) comGD/cglD 1999283..1999687 (-) 405 WP_000588013.1 competence type IV pilus minor pilin ComGD Machinery gene
  R8635_RS10425 (PC0062_20360) comGC/cglC 1999680..2000006 (-) 327 WP_000738630.1 comG operon protein ComGC Machinery gene
  R8635_RS10430 (PC0062_20370) comGB/cglB 2000008..2001024 (-) 1017 WP_075218762.1 competence type IV pilus assembly protein ComGB Machinery gene
  R8635_RS10435 (PC0062_20380) comGA/cglA/cilD 2000972..2001913 (-) 942 WP_000249571.1 competence type IV pilus ATPase ComGA Machinery gene
  R8635_RS10440 (PC0062_20390) - 2001989..2002354 (-) 366 WP_000286415.1 DUF1033 family protein -
  R8635_RS10445 (PC0062_20400) - 2002505..2003563 (-) 1059 WP_000649470.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12247.38 Da        Isoelectric Point: 9.8692

>NTDB_id=98304 R8635_RS10425 WP_000738630.1 1999680..2000006(-) (comGC/cglC) [Streptococcus pneumoniae strain PZ900700063]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKD
DGRITEEQAKAYKEYHDKNGEANRKVND

Nucleotide


Download         Length: 327 bp        

>NTDB_id=98304 R8635_RS10425 WP_000738630.1 1999680..2000006(-) (comGC/cglC) [Streptococcus pneumoniae strain PZ900700063]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAAATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGAAAAGAATGAAGATGCTAGCCTAAGCAAGTTAAAAGAC
GATGGGCGAATCACGGAAGAACAGGCTAAAGCTTATAAAGAATACCATGATAAAAATGGAGAAGCAAATCGTAAAGTCAA
TGATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae Rx1

96.296

100

0.963
  comGC/cglC Streptococcus pneumoniae D39

96.296

100

0.963
  comGC/cglC Streptococcus pneumoniae R6

96.296

100

0.963
  comGC/cglC Streptococcus pneumoniae TIGR4

95.37

100

0.954
  comGC/cglC Streptococcus mitis SK321

92.593

100

0.926
  comGC/cglC Streptococcus mitis NCTC 12261

94.898

90.741

0.861
  comYC Streptococcus gordonii str. Challis substr. CH1

67.961

95.37

0.648
  comYC Streptococcus mutans UA159

62.745

94.444

0.593
  comYC Streptococcus mutans UA140

62.745

94.444

0.593
  comGC Lactococcus lactis subsp. cremoris KW2

54.902

94.444

0.519
  comYC Streptococcus suis isolate S10

67.901

75

0.509
  comGC Staphylococcus aureus MW2

46.078

94.444

0.435
  comGC Staphylococcus aureus N315

46.078

94.444

0.435
  comGC Latilactobacillus sakei subsp. sakei 23K

45.349

79.63

0.361

Multiple sequence alignment