Detailed information NTG0098301

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: R8635_RS10410
• Genome accession: NZ_AP026924
• Coordinates: 1998594..1999055 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250540.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900700063
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1993594..2004055

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8635_RS10375 (PC0062_20260)	-	1993898..1994722 (-)	825	WP_001832473.1	membrane protein insertase YidC	-
R8635_RS10380 (PC0062_20270)	rnpA	1994697..1995068 (-)	372	WP_000739246.1	ribonuclease P protein component	-
R8635_RS10385	-	1995085..1995216 (-)	132	WP_000768904.1	hypothetical protein	-
R8635_RS10390 (PC0062_20280)	-	1995217..1996407 (-)	1191	WP_050245357.1	acetate kinase	-
R8635_RS10395 (PC0062_20290)	comYH	1996458..1997411 (-)	954	WP_050233486.1	class I SAM-dependent methyltransferase	Machinery gene
R8635_RS10400	-	1997472..1998066 (-)	595	Protein_2030	class I SAM-dependent methyltransferase	-
R8635_RS10405 (PC0062_20320)	comGG/cglG	1998203..1998616 (-)	414	WP_000265620.1	competence type IV pilus minor pilin ComGG	Machinery gene
R8635_RS10410	comGF/cglF	1998594..1999055 (-)	462	WP_000250540.1	competence type IV pilus minor pilin ComGF	Machinery gene
R8635_RS10415 (PC0062_20340)	comGE/cglE	1999018..1999320 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
R8635_RS10420 (PC0062_20350)	comGD/cglD	1999283..1999687 (-)	405	WP_000588013.1	competence type IV pilus minor pilin ComGD	Machinery gene
R8635_RS10425 (PC0062_20360)	comGC/cglC	1999680..2000006 (-)	327	WP_000738630.1	comG operon protein ComGC	Machinery gene
R8635_RS10430 (PC0062_20370)	comGB/cglB	2000008..2001024 (-)	1017	WP_075218762.1	competence type IV pilus assembly protein ComGB	Machinery gene
R8635_RS10435 (PC0062_20380)	comGA/cglA/cilD	2000972..2001913 (-)	942	WP_000249571.1	competence type IV pilus ATPase ComGA	Machinery gene
R8635_RS10440 (PC0062_20390)	-	2001989..2002354 (-)	366	WP_000286415.1	DUF1033 family protein	-
R8635_RS10445 (PC0062_20400)	-	2002505..2003563 (-)	1059	WP_000649470.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17850.40 Da
• Isoelectric Point: 8.0016

>NTDB_id=98301 R8635_RS10410 WP_000250540.1 1998594..1999055(-) (comGF/cglF) [Streptococcus pneumoniae strain PZ900700063]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEKS

Nucleotide

• Length: 462 bp

>NTDB_id=98301 R8635_RS10410 WP_000250540.1 1998594..1999055(-) (comGF/cglF) [Streptococcus pneumoniae strain PZ900700063]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTACTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAACTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	94.771	100	0.948
comGF/cglF	Streptococcus pneumoniae D39	94.771	100	0.948
comGF/cglF	Streptococcus pneumoniae R6	94.771	100	0.948
comGF/cglF	Streptococcus pneumoniae TIGR4	94.771	100	0.948
comGF/cglF	Streptococcus mitis SK321	93.464	100	0.935
comGF/cglF	Streptococcus mitis NCTC 12261	92.157	100	0.922