Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   R8635_RS10395 Genome accession   NZ_AP026924
Coordinates   1996458..1997411 (-) Length   317 a.a.
NCBI ID   WP_050233486.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700063     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1991458..2002411
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8635_RS10365 (PC0062_20240) - 1992219..1992842 (-) 624 WP_000932657.1 hypothetical protein -
  R8635_RS10370 (PC0062_20250) jag 1992893..1993879 (-) 987 WP_000260027.1 RNA-binding cell elongation regulator Jag/EloR -
  R8635_RS10375 (PC0062_20260) - 1993898..1994722 (-) 825 WP_001832473.1 membrane protein insertase YidC -
  R8635_RS10380 (PC0062_20270) rnpA 1994697..1995068 (-) 372 WP_000739246.1 ribonuclease P protein component -
  R8635_RS10385 - 1995085..1995216 (-) 132 WP_000768904.1 hypothetical protein -
  R8635_RS10390 (PC0062_20280) - 1995217..1996407 (-) 1191 WP_050245357.1 acetate kinase -
  R8635_RS10395 (PC0062_20290) comYH 1996458..1997411 (-) 954 WP_050233486.1 class I SAM-dependent methyltransferase Machinery gene
  R8635_RS10400 - 1997472..1998066 (-) 595 Protein_2030 class I SAM-dependent methyltransferase -
  R8635_RS10405 (PC0062_20320) comGG/cglG 1998203..1998616 (-) 414 WP_000265620.1 competence type IV pilus minor pilin ComGG Machinery gene
  R8635_RS10410 comGF/cglF 1998594..1999055 (-) 462 WP_000250540.1 competence type IV pilus minor pilin ComGF Machinery gene
  R8635_RS10415 (PC0062_20340) comGE/cglE 1999018..1999320 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  R8635_RS10420 (PC0062_20350) comGD/cglD 1999283..1999687 (-) 405 WP_000588013.1 competence type IV pilus minor pilin ComGD Machinery gene
  R8635_RS10425 (PC0062_20360) comGC/cglC 1999680..2000006 (-) 327 WP_000738630.1 comG operon protein ComGC Machinery gene
  R8635_RS10430 (PC0062_20370) comGB/cglB 2000008..2001024 (-) 1017 WP_075218762.1 competence type IV pilus assembly protein ComGB Machinery gene
  R8635_RS10435 (PC0062_20380) comGA/cglA/cilD 2000972..2001913 (-) 942 WP_000249571.1 competence type IV pilus ATPase ComGA Machinery gene
  R8635_RS10440 (PC0062_20390) - 2001989..2002354 (-) 366 WP_000286415.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35646.83 Da        Isoelectric Point: 4.2585

>NTDB_id=98299 R8635_RS10395 WP_050233486.1 1996458..1997411(-) (comYH) [Streptococcus pneumoniae strain PZ900700063]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELEQVKDNNQTLKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFTEEEITILEMGSGMGILGATFLTSLTKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SNLLKVWLKEEASLVAMISLPENLFANAKQSKTIFILQKKSEVAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=98299 R8635_RS10395 WP_050233486.1 1996458..1997411(-) (comYH) [Streptococcus pneumoniae strain PZ900700063]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAACAGCATCTATCTGGATGGTGAGACTGAGCTAGAACAGGTCAAAGACAACAATC
AGACCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACGCCAGATGCTATTGCCTTACTTTTGGTATTTATTGTGGAAGAGTTGTTTAC
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTTTGGGCGCTACTTTCTTGACCTCGCTTACTAAAA
AGGTGGATTATTTGGGAATGGAAGTGGATGATTTGCTGATTGATTTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGTGATGTGGTCATCAGCGACTTGCCTGTTGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGTCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGACTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTAATTTGTTGAAAGTCTGGTTGAAAGAGGAGGCAAGTCTGGTTGCTATGATTAGTTTACCTGAAAATCTCTTTGCTAA
TGCTAAACAATCTAAGACTATTTTTATCCTACAGAAGAAAAGTGAAGTAGCAGTAGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.952

98.738

0.543
  comYH Streptococcus mutans UA159

54.633

98.738

0.539

Multiple sequence alignment