Detailed information NTG0098296

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: R8635_RS10105
• Genome accession: NZ_AP026924
• Coordinates: 1949639..1950649 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain PZ900700063
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1944639..1955649

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8635_RS10080	-	1945938..1946232 (-)	295	Protein_1980	hypothetical protein	-
R8635_RS10085 (PC0062_19830)	-	1946394..1946846 (+)	453	WP_000079154.1	universal stress protein	-
R8635_RS10090 (PC0062_19840)	-	1946881..1948269 (-)	1389	WP_000453139.1	Cof-type HAD-IIB family hydrolase	-
R8635_RS10095 (PC0062_19850)	-	1948335..1949297 (+)	963	WP_001124779.1	asparaginase	-
R8635_RS10100 (PC0062_19860)	-	1949294..1949575 (-)	282	WP_001092043.1	hypothetical protein	-
R8635_RS10105 (PC0062_19870)	ccpA	1949639..1950649 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
R8635_RS10110 (PC0062_19880)	-	1951074..1951673 (-)	600	WP_000866729.1	response regulator transcription factor	-
R8635_RS10115 (PC0062_19890)	-	1951675..1952772 (-)	1098	WP_281057021.1	sensor histidine kinase	-
R8635_RS10120 (PC0062_19900)	-	1952772..1953509 (-)	738	WP_023396473.1	ABC transporter permease	-
R8635_RS10125 (PC0062_19910)	-	1953511..1954395 (-)	885	WP_050211291.1	ABC transporter ATP-binding protein	-
R8635_RS10130 (PC0062_19920)	-	1954382..1954576 (-)	195	WP_000820185.1	hypothetical protein	-
R8635_RS10135 (PC0062_19930)	-	1954573..1954779 (-)	207	WP_000503440.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=98296 R8635_RS10105 WP_000990607.1 1949639..1950649(-) (ccpA) [Streptococcus pneumoniae strain PZ900700063]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=98296 R8635_RS10105 WP_000990607.1 1949639..1950649(-) (ccpA) [Streptococcus pneumoniae strain PZ900700063]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGCTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAAGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCTATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568