Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGC/cglC   Type   Machinery gene
Locus tag   U0449_RS06180 Genome accession   NZ_CP139862
Coordinates   1230635..1230961 (+) Length   108 a.a.
NCBI ID   WP_000738630.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 05H0020-2     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 1225635..1235961
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0449_RS06155 nagA 1225764..1226915 (+) 1152 WP_050087279.1 N-acetylglucosamine-6-phosphate deacetylase -
  U0449_RS06160 - 1227078..1228136 (+) 1059 WP_000649473.1 zinc-dependent alcohol dehydrogenase family protein -
  U0449_RS06165 - 1228287..1228652 (+) 366 WP_000286415.1 DUF1033 family protein -
  U0449_RS06170 comGA/cglA/cilD 1228728..1229669 (+) 942 WP_000249567.1 competence type IV pilus ATPase ComGA Machinery gene
  U0449_RS06175 comGB/cglB 1229617..1230633 (+) 1017 WP_078136505.1 competence type IV pilus assembly protein ComGB Machinery gene
  U0449_RS06180 comGC/cglC 1230635..1230961 (+) 327 WP_000738630.1 comG operon protein ComGC Machinery gene
  U0449_RS06185 comGD/cglD 1230954..1231358 (+) 405 WP_322398090.1 competence type IV pilus minor pilin ComGD Machinery gene
  U0449_RS06190 comGE/cglE 1231321..1231623 (+) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  U0449_RS06195 comGF/cglF 1231586..1232047 (+) 462 WP_000250540.1 competence type IV pilus minor pilin ComGF Machinery gene
  U0449_RS06200 comGG/cglG 1232025..1232438 (+) 414 WP_000265620.1 competence type IV pilus minor pilin ComGG Machinery gene
  U0449_RS06205 - 1232575..1233169 (+) 595 Protein_1212 class I SAM-dependent methyltransferase -
  U0449_RS06210 comYH 1233230..1234183 (+) 954 WP_050219032.1 class I SAM-dependent methyltransferase Machinery gene
  U0449_RS06215 - 1234234..1235424 (+) 1191 WP_000167753.1 acetate kinase -
  U0449_RS06220 - 1235425..1235556 (+) 132 WP_000768904.1 hypothetical protein -
  U0449_RS06225 rnpA 1235573..1235944 (+) 372 WP_000739246.1 ribonuclease P protein component -

Sequence


Protein


Download         Length: 108 a.a.        Molecular weight: 12247.38 Da        Isoelectric Point: 9.8692

>NTDB_id=911494 U0449_RS06180 WP_000738630.1 1230635..1230961(+) (comGC/cglC) [Streptococcus pneumoniae strain 05H0020-2]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKD
DGRITEEQAKAYKEYHDKNGEANRKVND

Nucleotide


Download         Length: 327 bp        

>NTDB_id=911494 U0449_RS06180 WP_000738630.1 1230635..1230961(+) (comGC/cglC) [Streptococcus pneumoniae strain 05H0020-2]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAAATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGAAAAGAATGAAGATGCTAGCCTAAGCAAGTTAAAAGAC
GATGGGCGAATCACGGAAGAACAGGCTAAAGCTTATAAAGAATACCATGATAAAAATGGAGAAGCAAATCGTAAAGTCAA
TGATTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae Rx1

96.296

100

0.963

  comGC/cglC Streptococcus pneumoniae D39

96.296

100

0.963

  comGC/cglC Streptococcus pneumoniae R6

96.296

100

0.963

  comGC/cglC Streptococcus pneumoniae TIGR4

95.37

100

0.954

  comGC/cglC Streptococcus mitis SK321

92.593

100

0.926

  comGC/cglC Streptococcus mitis NCTC 12261

94.898

90.741

0.861

  comYC Streptococcus gordonii str. Challis substr. CH1

67.961

95.37

0.648

  comYC Streptococcus mutans UA159

62.745

94.444

0.593

  comYC Streptococcus mutans UA140

62.745

94.444

0.593

  comGC Lactococcus lactis subsp. cremoris KW2

54.902

94.444

0.519

  comYC Streptococcus suis isolate S10

67.901

75

0.509

  comGC Staphylococcus aureus MW2

46.078

94.444

0.435

  comGC Staphylococcus aureus N315

46.078

94.444

0.435

  comGC Latilactobacillus sakei subsp. sakei 23K

45.349

79.63

0.361