Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   U0449_RS06210 Genome accession   NZ_CP139862
Coordinates   1233230..1234183 (+) Length   317 a.a.
NCBI ID   WP_050219032.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 05H0020-2     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1228230..1239183
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0449_RS06165 - 1228287..1228652 (+) 366 WP_000286415.1 DUF1033 family protein -
  U0449_RS06170 comGA/cglA/cilD 1228728..1229669 (+) 942 WP_000249567.1 competence type IV pilus ATPase ComGA Machinery gene
  U0449_RS06175 comGB/cglB 1229617..1230633 (+) 1017 WP_078136505.1 competence type IV pilus assembly protein ComGB Machinery gene
  U0449_RS06180 comGC/cglC 1230635..1230961 (+) 327 WP_000738630.1 comG operon protein ComGC Machinery gene
  U0449_RS06185 comGD/cglD 1230954..1231358 (+) 405 WP_322398090.1 competence type IV pilus minor pilin ComGD Machinery gene
  U0449_RS06190 comGE/cglE 1231321..1231623 (+) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  U0449_RS06195 comGF/cglF 1231586..1232047 (+) 462 WP_000250540.1 competence type IV pilus minor pilin ComGF Machinery gene
  U0449_RS06200 comGG/cglG 1232025..1232438 (+) 414 WP_000265620.1 competence type IV pilus minor pilin ComGG Machinery gene
  U0449_RS06205 - 1232575..1233169 (+) 595 Protein_1212 class I SAM-dependent methyltransferase -
  U0449_RS06210 comYH 1233230..1234183 (+) 954 WP_050219032.1 class I SAM-dependent methyltransferase Machinery gene
  U0449_RS06215 - 1234234..1235424 (+) 1191 WP_000167753.1 acetate kinase -
  U0449_RS06220 - 1235425..1235556 (+) 132 WP_000768904.1 hypothetical protein -
  U0449_RS06225 rnpA 1235573..1235944 (+) 372 WP_000739246.1 ribonuclease P protein component -
  U0449_RS06230 - 1235919..1236743 (+) 825 WP_000727904.1 membrane protein insertase YidC -
  U0449_RS06235 jag 1236762..1237748 (+) 987 WP_000260011.1 RNA-binding cell elongation regulator Jag/EloR -
  U0449_RS06240 - 1237799..1238422 (+) 624 WP_000932632.1 hypothetical protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35687.80 Da        Isoelectric Point: 4.2052

>NTDB_id=911499 U0449_RS06210 WP_050219032.1 1233230..1234183(+) (comYH) [Streptococcus pneumoniae strain 05H0020-2]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFTEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFILQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=911499 U0449_RS06210 WP_050219032.1 1233230..1234183(+) (comYH) [Streptococcus pneumoniae strain 05H0020-2]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAACAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC
AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCGGATGCTATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAC
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAGTGGATGATTTACTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTTGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGCTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGAATGGCTGAAAGAAGAGGCGAGTCTGGTTGCTATGATTAGTCTGCCTGAAAACCTCTTTGCTAA
TGCCAAACAATCTAAGACTATTTTTATCTTACAGAAGAAAAATGAAATAGCAGTAGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.633

98.738

0.539
  comYH Streptococcus mutans UA159

54.313

98.738

0.536