Detailed information NTG0896186

Bioinformatically predicted

Overview

• Name: comGC/cglC
• Type: Machinery gene
• Locus tag: R4701_RS06300
• Genome accession: NZ_CP137114
• Coordinates: 1252225..1252551 (+)
• Length: 108 a.a.
• NCBI ID: WP_000738630.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 15P3054
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1247225..1257551

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4701_RS06275	nagA	1247354..1248505 (+)	1152	WP_001134457.1	N-acetylglucosamine-6-phosphate deacetylase	-
R4701_RS06280	-	1248668..1249726 (+)	1059	WP_000649466.1	zinc-dependent alcohol dehydrogenase family protein	-
R4701_RS06285	-	1249877..1250242 (+)	366	WP_000286415.1	DUF1033 family protein	-
R4701_RS06290	comGA/cglA/cilD	1250318..1251259 (+)	942	WP_000249571.1	competence type IV pilus ATPase ComGA	Machinery gene
R4701_RS06295	comGB/cglB	1251207..1252223 (+)	1017	WP_075218762.1	competence type IV pilus assembly protein ComGB	Machinery gene
R4701_RS06300	comGC/cglC	1252225..1252551 (+)	327	WP_000738630.1	comG operon protein ComGC	Machinery gene
R4701_RS06305	comGD/cglD	1252544..1252948 (+)	405	WP_000588023.1	competence type IV pilus minor pilin ComGD	Machinery gene
R4701_RS06310	comGE/cglE	1252911..1253213 (+)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
R4701_RS06315	comGF/cglF	1253176..1253637 (+)	462	WP_000250540.1	competence type IV pilus minor pilin ComGF	Machinery gene
R4701_RS06320	comGG/cglG	1253615..1254028 (+)	414	WP_000265620.1	competence type IV pilus minor pilin ComGG	Machinery gene
R4701_RS06325	-	1254165..1254759 (+)	595	Protein_1234	class I SAM-dependent methyltransferase	-
R4701_RS06330	comYH	1254820..1255773 (+)	954	WP_000345126.1	class I SAM-dependent methyltransferase	Machinery gene
R4701_RS06335	-	1255824..1257014 (+)	1191	WP_000167757.1	acetate kinase	-
R4701_RS06340	-	1257015..1257146 (+)	132	WP_000768904.1	hypothetical protein	-
R4701_RS06345	rnpA	1257163..1257534 (+)	372	WP_000739246.1	ribonuclease P protein component	-

Sequence

Protein

• Length: 108 a.a.
• Molecular weight: 12247.38 Da
• Isoelectric Point: 9.8692

>NTDB_id=896186 R4701_RS06300 WP_000738630.1 1252225..1252551(+) (comGC/cglC) [Streptococcus pneumoniae strain 15P3054]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKD
DGRITEEQAKAYKEYHDKNGEANRKVND

Nucleotide

• Length: 327 bp

>NTDB_id=896186 R4701_RS06300 WP_000738630.1 1252225..1252551(+) (comGC/cglC) [Streptococcus pneumoniae strain 15P3054]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAAATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGAAAAGAATGAAGATGCTAGCCTAAGCAAGTTAAAAGAC
GATGGGCGAATCACGGAAGAACAGGCTAAAGCTTATAAAGAATACCATGATAAAAATGGAGAAGCAAATCGTAAAGTCAA
TGATTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (11-34)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC/cglC	Streptococcus pneumoniae Rx1	96.296	100	0.963
comGC/cglC	Streptococcus pneumoniae D39	96.296	100	0.963
comGC/cglC	Streptococcus pneumoniae R6	96.296	100	0.963
comGC/cglC	Streptococcus pneumoniae TIGR4	95.37	100	0.954
comGC/cglC	Streptococcus mitis SK321	92.593	100	0.926
comGC/cglC	Streptococcus mitis NCTC 12261	94.898	90.741	0.861
comYC	Streptococcus gordonii str. Challis substr. CH1	67.961	95.37	0.648
comYC	Streptococcus mutans UA159	62.745	94.444	0.593
comYC	Streptococcus mutans UA140	62.745	94.444	0.593
comGC	Lactococcus lactis subsp. cremoris KW2	54.902	94.444	0.519
comYC	Streptococcus suis isolate S10	67.901	75	0.509
comGC	Staphylococcus aureus MW2	46.078	94.444	0.435
comGC	Staphylococcus aureus N315	46.078	94.444	0.435
comGC	Latilactobacillus sakei subsp. sakei 23K	45.349	79.63	0.361