Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   R4701_RS06310 Genome accession   NZ_CP137114
Coordinates   1252911..1253213 (+) Length   100 a.a.
NCBI ID   WP_000413382.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 15P3054     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1247911..1258213
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4701_RS06280 - 1248668..1249726 (+) 1059 WP_000649466.1 zinc-dependent alcohol dehydrogenase family protein -
  R4701_RS06285 - 1249877..1250242 (+) 366 WP_000286415.1 DUF1033 family protein -
  R4701_RS06290 comGA/cglA/cilD 1250318..1251259 (+) 942 WP_000249571.1 competence type IV pilus ATPase ComGA Machinery gene
  R4701_RS06295 comGB/cglB 1251207..1252223 (+) 1017 WP_075218762.1 competence type IV pilus assembly protein ComGB Machinery gene
  R4701_RS06300 comGC/cglC 1252225..1252551 (+) 327 WP_000738630.1 comG operon protein ComGC Machinery gene
  R4701_RS06305 comGD/cglD 1252544..1252948 (+) 405 WP_000588023.1 competence type IV pilus minor pilin ComGD Machinery gene
  R4701_RS06310 comGE/cglE 1252911..1253213 (+) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  R4701_RS06315 comGF/cglF 1253176..1253637 (+) 462 WP_000250540.1 competence type IV pilus minor pilin ComGF Machinery gene
  R4701_RS06320 comGG/cglG 1253615..1254028 (+) 414 WP_000265620.1 competence type IV pilus minor pilin ComGG Machinery gene
  R4701_RS06325 - 1254165..1254759 (+) 595 Protein_1234 class I SAM-dependent methyltransferase -
  R4701_RS06330 comYH 1254820..1255773 (+) 954 WP_000345126.1 class I SAM-dependent methyltransferase Machinery gene
  R4701_RS06335 - 1255824..1257014 (+) 1191 WP_000167757.1 acetate kinase -
  R4701_RS06340 - 1257015..1257146 (+) 132 WP_000768904.1 hypothetical protein -
  R4701_RS06345 rnpA 1257163..1257534 (+) 372 WP_000739246.1 ribonuclease P protein component -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11108.08 Da        Isoelectric Point: 9.7273

>NTDB_id=896188 R4701_RS06310 WP_000413382.1 1252911..1253213(+) (comGE/cglE) [Streptococcus pneumoniae strain 15P3054]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=896188 R4701_RS06310 WP_000413382.1 1252911..1253213(+) (comGE/cglE) [Streptococcus pneumoniae strain 15P3054]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCCTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

100

100

1
  comGE/cglE Streptococcus pneumoniae D39

100

100

1
  comGE/cglE Streptococcus pneumoniae R6

100

100

1
  comGE/cglE Streptococcus pneumoniae TIGR4

100

100

1
  comGE/cglE Streptococcus mitis NCTC 12261

98

100

0.98
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

44.444

90

0.4
  comYE Streptococcus mutans UA159

44.444

90

0.4