Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   R4701_RS06330 Genome accession   NZ_CP137114
Coordinates   1254820..1255773 (+) Length   317 a.a.
NCBI ID   WP_000345126.1    Uniprot ID   A0A0F7YBB9
Organism   Streptococcus pneumoniae strain 15P3054     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1249820..1260773
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4701_RS06285 - 1249877..1250242 (+) 366 WP_000286415.1 DUF1033 family protein -
  R4701_RS06290 comGA/cglA/cilD 1250318..1251259 (+) 942 WP_000249571.1 competence type IV pilus ATPase ComGA Machinery gene
  R4701_RS06295 comGB/cglB 1251207..1252223 (+) 1017 WP_075218762.1 competence type IV pilus assembly protein ComGB Machinery gene
  R4701_RS06300 comGC/cglC 1252225..1252551 (+) 327 WP_000738630.1 comG operon protein ComGC Machinery gene
  R4701_RS06305 comGD/cglD 1252544..1252948 (+) 405 WP_000588023.1 competence type IV pilus minor pilin ComGD Machinery gene
  R4701_RS06310 comGE/cglE 1252911..1253213 (+) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  R4701_RS06315 comGF/cglF 1253176..1253637 (+) 462 WP_000250540.1 competence type IV pilus minor pilin ComGF Machinery gene
  R4701_RS06320 comGG/cglG 1253615..1254028 (+) 414 WP_000265620.1 competence type IV pilus minor pilin ComGG Machinery gene
  R4701_RS06325 - 1254165..1254759 (+) 595 Protein_1234 class I SAM-dependent methyltransferase -
  R4701_RS06330 comYH 1254820..1255773 (+) 954 WP_000345126.1 class I SAM-dependent methyltransferase Machinery gene
  R4701_RS06335 - 1255824..1257014 (+) 1191 WP_000167757.1 acetate kinase -
  R4701_RS06340 - 1257015..1257146 (+) 132 WP_000768904.1 hypothetical protein -
  R4701_RS06345 rnpA 1257163..1257534 (+) 372 WP_000739246.1 ribonuclease P protein component -
  R4701_RS06350 - 1257509..1258333 (+) 825 WP_000727904.1 membrane protein insertase YidC -
  R4701_RS06355 jag 1258352..1259338 (+) 987 WP_000260018.1 RNA-binding cell elongation regulator Jag/EloR -
  R4701_RS06360 - 1259389..1260012 (+) 624 WP_000932660.1 hypothetical protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35714.87 Da        Isoelectric Point: 4.2434

>NTDB_id=896191 R4701_RS06330 WP_000345126.1 1254820..1255773(+) (comYH) [Streptococcus pneumoniae strain 15P3054]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFILQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=896191 R4701_RS06330 WP_000345126.1 1254820..1255773(+) (comYH) [Streptococcus pneumoniae strain 15P3054]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAACAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC
AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCGGATGCTATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAGTGGATGATTTACTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTTGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGCTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGAATGGCTGAAAGAAGAGGCGAGTCTGGTTGCTATGATTAGTCTGCCTGAAAACCTCTTTGCTAA
TGCCAAACAATCTAAGACTATTTTTATCTTACAGAAGAAAAATGAAATAGCAGTAGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F7YBB9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.633

98.738

0.539
  comYH Streptococcus mutans UA159

54.313

98.738

0.536