Detailed information NTG0895179

Bioinformatically predicted

Overview

• Name: comGC/cglC
• Type: Machinery gene
• Locus tag: R4710_RS04575
• Genome accession: NZ_CP137101
• Coordinates: 852089..852415 (-)
• Length: 108 a.a.
• NCBI ID: WP_000738632.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 16P2012-2
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 847089..857415

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4710_RS04530	rnpA	847106..847477 (-)	372	WP_000739246.1	ribonuclease P protein component	-
R4710_RS04535	-	847494..847625 (-)	132	WP_000768904.1	hypothetical protein	-
R4710_RS04540	-	847626..848816 (-)	1191	WP_000167766.1	acetate kinase	-
R4710_RS04545	comYH	848867..849820 (-)	954	WP_000345130.1	class I SAM-dependent methyltransferase	Machinery gene
R4710_RS04550	-	849881..850475 (-)	595	Protein_869	class I SAM-dependent methyltransferase	-
R4710_RS04555	comGG/cglG	850612..851025 (-)	414	WP_000265631.1	competence type IV pilus minor pilin ComGG	Machinery gene
R4710_RS04560	comGF/cglF	851003..851464 (-)	462	WP_000250531.1	competence type IV pilus minor pilin ComGF	Machinery gene
R4710_RS04565	comGE/cglE	851427..851729 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
R4710_RS04570	comGD/cglD	851692..852096 (-)	405	WP_000588020.1	competence type IV pilus minor pilin ComGD	Machinery gene
R4710_RS04575	comGC/cglC	852089..852415 (-)	327	WP_000738632.1	comG operon protein ComGC	Machinery gene
R4710_RS04580	comGB/cglB	852417..853433 (-)	1017	WP_075218762.1	competence type IV pilus assembly protein ComGB	Machinery gene
R4710_RS04585	comGA/cglA/cilD	853381..854322 (-)	942	WP_000249571.1	competence type IV pilus ATPase ComGA	Machinery gene
R4710_RS04590	-	854398..854763 (-)	366	WP_000286415.1	DUF1033 family protein	-
R4710_RS04595	-	854914..855972 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-
R4710_RS04600	nagA	856135..857286 (-)	1152	WP_001134457.1	N-acetylglucosamine-6-phosphate deacetylase	-

Sequence

Protein

• Length: 108 a.a.
• Molecular weight: 12180.34 Da
• Isoelectric Point: 10.0305

>NTDB_id=895179 R4710_RS04575 WP_000738632.1 852089..852415(-) (comGC/cglC) [Streptococcus pneumoniae strain 16P2012-2]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKD
DGRITEEQVKAYKEYNDKNGGANRKVND

Nucleotide

• Length: 327 bp

>NTDB_id=895179 R4710_RS04575 WP_000738632.1 852089..852415(-) (comGC/cglC) [Streptococcus pneumoniae strain 16P2012-2]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAGATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGAAAAGAATGAAGATGCTAGCCTAAGCAAGTTAAAAGAC
GATGGGCGAATCACGGAAGAACAGGTTAAAGCTTATAAAGAATACAATGATAAAAATGGAGGAGCAAATCGTAAAGTCAA
TGATTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (11-34)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC/cglC	Streptococcus pneumoniae TIGR4	96.296	100	0.963
comGC/cglC	Streptococcus pneumoniae Rx1	95.37	100	0.954
comGC/cglC	Streptococcus pneumoniae D39	95.37	100	0.954
comGC/cglC	Streptococcus pneumoniae R6	95.37	100	0.954
comGC/cglC	Streptococcus mitis SK321	92.593	100	0.926
comGC/cglC	Streptococcus mitis NCTC 12261	91.919	91.667	0.843
comYC	Streptococcus gordonii str. Challis substr. CH1	66.99	95.37	0.639
comYC	Streptococcus mutans UA159	61.765	94.444	0.583
comYC	Streptococcus mutans UA140	61.765	94.444	0.583
comGC	Lactococcus lactis subsp. cremoris KW2	55.882	94.444	0.528
comYC	Streptococcus suis isolate S10	66.667	75	0.5
comGC	Staphylococcus aureus MW2	48.837	79.63	0.389
comGC	Staphylococcus aureus N315	48.837	79.63	0.389
comGC	Latilactobacillus sakei subsp. sakei 23K	45.349	79.63	0.361