Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   R4710_RS04545 Genome accession   NZ_CP137101
Coordinates   848867..849820 (-) Length   317 a.a.
NCBI ID   WP_000345130.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 16P2012-2     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 843867..854820
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4710_RS04515 - 844628..845251 (-) 624 WP_000932660.1 hypothetical protein -
  R4710_RS04520 jag 845302..846288 (-) 987 WP_000260018.1 RNA-binding cell elongation regulator Jag/EloR -
  R4710_RS04525 - 846307..847131 (-) 825 WP_000727904.1 membrane protein insertase YidC -
  R4710_RS04530 rnpA 847106..847477 (-) 372 WP_000739246.1 ribonuclease P protein component -
  R4710_RS04535 - 847494..847625 (-) 132 WP_000768904.1 hypothetical protein -
  R4710_RS04540 - 847626..848816 (-) 1191 WP_000167766.1 acetate kinase -
  R4710_RS04545 comYH 848867..849820 (-) 954 WP_000345130.1 class I SAM-dependent methyltransferase Machinery gene
  R4710_RS04550 - 849881..850475 (-) 595 Protein_869 class I SAM-dependent methyltransferase -
  R4710_RS04555 comGG/cglG 850612..851025 (-) 414 WP_000265631.1 competence type IV pilus minor pilin ComGG Machinery gene
  R4710_RS04560 comGF/cglF 851003..851464 (-) 462 WP_000250531.1 competence type IV pilus minor pilin ComGF Machinery gene
  R4710_RS04565 comGE/cglE 851427..851729 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  R4710_RS04570 comGD/cglD 851692..852096 (-) 405 WP_000588020.1 competence type IV pilus minor pilin ComGD Machinery gene
  R4710_RS04575 comGC/cglC 852089..852415 (-) 327 WP_000738632.1 comG operon protein ComGC Machinery gene
  R4710_RS04580 comGB/cglB 852417..853433 (-) 1017 WP_075218762.1 competence type IV pilus assembly protein ComGB Machinery gene
  R4710_RS04585 comGA/cglA/cilD 853381..854322 (-) 942 WP_000249571.1 competence type IV pilus ATPase ComGA Machinery gene
  R4710_RS04590 - 854398..854763 (-) 366 WP_000286415.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35642.89 Da        Isoelectric Point: 4.3259

>NTDB_id=895174 R4710_RS04545 WP_000345130.1 848867..849820(-) (comYH) [Streptococcus pneumoniae strain 16P2012-2]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLTKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SNLLKVWLKEEASLVAMISLPENLFANAKQSKTIFILQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=895174 R4710_RS04545 WP_000345130.1 848867..849820(-) (comYH) [Streptococcus pneumoniae strain 16P2012-2]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAATAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC
AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACGCCAGATGCTATTGCCTTACTTTTGGTGTTTATTGTGGAAGAGCTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTTTGGGCGCTACTTTCTTGACCTCGCTTACTAAAA
AGGTGGATTATTTGGGAATGGAAGTGGATGATTTGCTGATTGATTTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGTGATGTGGTCATCAGCGACTTGCCTGTTGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGTCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGACTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTAATTTGTTGAAAGTCTGGTTGAAAGAGGAGGCAAGTCTGGTTGCTATGATTAGTTTACCTGAAAATCTCTTTGCTAA
TGCTAAACAATCTAAGACTATTTTTATCCTACAGAAGAAAAGTGAAATAGCAGTAGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.952

98.738

0.543
  comYH Streptococcus mutans UA159

54.633

98.738

0.539