Detailed information NTG0895176

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: R4710_RS04560
• Genome accession: NZ_CP137101
• Coordinates: 851003..851464 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250531.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 16P2012-2
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 846003..856464

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4710_RS04525	-	846307..847131 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
R4710_RS04530	rnpA	847106..847477 (-)	372	WP_000739246.1	ribonuclease P protein component	-
R4710_RS04535	-	847494..847625 (-)	132	WP_000768904.1	hypothetical protein	-
R4710_RS04540	-	847626..848816 (-)	1191	WP_000167766.1	acetate kinase	-
R4710_RS04545	comYH	848867..849820 (-)	954	WP_000345130.1	class I SAM-dependent methyltransferase	Machinery gene
R4710_RS04550	-	849881..850475 (-)	595	Protein_869	class I SAM-dependent methyltransferase	-
R4710_RS04555	comGG/cglG	850612..851025 (-)	414	WP_000265631.1	competence type IV pilus minor pilin ComGG	Machinery gene
R4710_RS04560	comGF/cglF	851003..851464 (-)	462	WP_000250531.1	competence type IV pilus minor pilin ComGF	Machinery gene
R4710_RS04565	comGE/cglE	851427..851729 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
R4710_RS04570	comGD/cglD	851692..852096 (-)	405	WP_000588020.1	competence type IV pilus minor pilin ComGD	Machinery gene
R4710_RS04575	comGC/cglC	852089..852415 (-)	327	WP_000738632.1	comG operon protein ComGC	Machinery gene
R4710_RS04580	comGB/cglB	852417..853433 (-)	1017	WP_075218762.1	competence type IV pilus assembly protein ComGB	Machinery gene
R4710_RS04585	comGA/cglA/cilD	853381..854322 (-)	942	WP_000249571.1	competence type IV pilus ATPase ComGA	Machinery gene
R4710_RS04590	-	854398..854763 (-)	366	WP_000286415.1	DUF1033 family protein	-
R4710_RS04595	-	854914..855972 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17849.37 Da
• Isoelectric Point: 6.4832

>NTDB_id=895176 R4710_RS04560 WP_000250531.1 851003..851464(-) (comGF/cglF) [Streptococcus pneumoniae strain 16P2012-2]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLISEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES

Nucleotide

• Length: 462 bp

>NTDB_id=895176 R4710_RS04560 WP_000250531.1 851003..851464(-) (comGF/cglF) [Streptococcus pneumoniae strain 16P2012-2]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAGCTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGTAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAGAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	95.425	100	0.954
comGF/cglF	Streptococcus pneumoniae D39	95.425	100	0.954
comGF/cglF	Streptococcus pneumoniae R6	95.425	100	0.954
comGF/cglF	Streptococcus pneumoniae TIGR4	95.425	100	0.954
comGF/cglF	Streptococcus mitis SK321	92.81	100	0.928
comGF/cglF	Streptococcus mitis NCTC 12261	91.503	100	0.915