Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   LBA42_RS01135 Genome accession   NZ_CP145437
Coordinates   214901..216889 (+) Length   662 a.a.
NCBI ID   WP_000607033.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain HAC 39-1996     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 209901..221889
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LBA42_RS01120 (LBA42_01120) - 210793..211533 (-) 741 WP_001096339.1 amino acid ABC transporter ATP-binding protein -
  LBA42_RS01125 (LBA42_01125) - 211533..213698 (-) 2166 WP_000726260.1 ABC transporter substrate-binding protein/permease -
  LBA42_RS01130 (LBA42_01130) - 213871..214824 (+) 954 WP_000792099.1 CPBP family intramembrane glutamic endopeptidase -
  LBA42_RS01135 (LBA42_01135) uvrB 214901..216889 (+) 1989 WP_000607033.1 excinuclease ABC subunit UvrB Machinery gene
  LBA42_RS01140 (LBA42_01140) - 216899..217462 (+) 564 WP_000639842.1 GNAT family protein -
  LBA42_RS01145 (LBA42_01145) - 217428..217916 (+) 489 WP_000216006.1 GNAT family N-acetyltransferase -
  LBA42_RS01150 (LBA42_01150) - 217989..218456 (+) 468 WP_000091537.1 8-oxo-dGTP diphosphatase -
  LBA42_RS01155 (LBA42_01155) - 218453..218968 (-) 516 WP_000159176.1 transcription repressor NadR -
  LBA42_RS01160 (LBA42_01160) - 218980..219507 (-) 528 WP_001097402.1 ECF transporter S component -
  LBA42_RS01165 (LBA42_01165) - 219789..220352 (-) 564 WP_000747408.1 ECF transporter S component -
  LBA42_RS01170 (LBA42_01170) coaC 220336..220887 (-) 552 WP_001284128.1 phosphopantothenoylcysteine decarboxylase -
  LBA42_RS01175 (LBA42_01175) coaB 220899..221588 (-) 690 WP_000699494.1 phosphopantothenate--cysteine ligase -

Sequence

Protein


Download         Length: 662 a.a.        Molecular weight: 75867.91 Da        Isoelectric Point: 4.5676

>NTDB_id=850693 LBA42_RS01135 WP_000607033.1 214901..216889(+) (uvrB) [Streptococcus pneumoniae strain HAC 39-1996]
MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMGATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYG
EFKEFFPENAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFRVEFFGDEIDRIREVEALTGQVL
GEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQLAVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDG
RSEGEPPYTLLDFFPDDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKNERTFITTLTKKMAEDLTDYFKEMGIKVKYM
HSDIKTLERTEIIRDLRLGVFDVLVGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADT
VTQSMQRAIDETARRRKIQMTYNEEHDIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQERKELVKKLEKQMQEAV
EVLDFELAAQIRDMMLEVKVLD

Nucleotide


Download         Length: 1989 bp        

>NTDB_id=850693 LBA42_RS01135 WP_000607033.1 214901..216889(+) (uvrB) [Streptococcus pneumoniae strain HAC 39-1996]
ATGATCAATCACATTACAGATAATCAATTTAAACTAGTATCAAAATATCAACCATCAGGAGATCAACCCCAAGCTATCGA
GCAGTTGGTGGATAACATTGAGGGGGGAGAAAAAGCTCAGATTCTGATGGGGGCGACTGGAACAGGGAAGACCTATACTA
TGAGTCAGGTCATTTCTAAAGTCAATAAACCAACTCTGGTTATTGCCCACAATAAAACTCTGGCTGGTCAGCTCTATGGG
GAGTTTAAGGAATTTTTCCCTGAAAATGCAGTTGAGTATTTCGTATCCTACTATGATTATTACCAGCCAGAGGCCTATGT
CCCTTCTAGCGATACCTATATTGAGAAGGATAGTTCTGTCAATGACGAGATTGACAAGCTTCGCCACTCAGCTACCTCAG
CCCTTTTGGAGCGTAATGATGTTATTGTCGTGGCCTCAGTCTCTTGTATCTATGGTTTGGGTTCGCCCAAGGAATACGCT
GATAGTGTCGTTAGTCTCCGTCCTGGTCTAGAGATTTCTCGTGATAAACTCTTGAATGACTTGGTCGATATTCAGTTTGA
ACGTAATGATATTGATTTCCAACGCGGAAGATTTCGCGTTCGTGGGGATGTGGTAGAGATTTTCCCAGCTTCCCGAGATG
AACATGCCTTTCGAGTAGAATTTTTTGGAGACGAAATTGACCGTATTCGTGAAGTTGAGGCTCTGACAGGTCAGGTGTTG
GGAGAAGTGGATCATTTAGCGATTTTCCCAGCGACACACTTTGTGACCAATGACGACCACATGGAAGTTGCCATTGCAAA
GATTCAGGCCGAGTTGGAAGAACAATTAGCTGTCTTTGAAAAGGAAGGTAAACTGCTTGAAGCCCAGCGTTTGAAACAGC
GGACAGAGTATGATATCGAAATGTTGCGTGAGATGGGCTATACCAATGGGGTTGAGAACTATTCACGACACATGGATGGA
CGGAGCGAAGGAGAGCCTCCTTATACGCTCTTAGATTTCTTCCCAGATGATTTCTTAATTATGATTGACGAGAGTCACAT
GACCATGGGGCAAATCAAGGGCATGTACAATGGAGACCGTTCGCGTAAAGAAATGCTGGTTAATTATGGCTTCCGATTGC
CGTCTGCTTTGGACAATCGTCCTCTCCGTCGGGAGGAGTTTGAGAGTCACGTTCATCAGATTGTTTACGTTTCAGCGACA
CCTGGTGACTATGAAAATGAACAGACTGAGACAGTGATTGAGCAAATCATTCGTCCAACGGGACTCTTGGATCCTGAAGT
GGAAGTCCGTCCGACTATGGGACAGATTGATGACCTCTTGGGTGAAATCAATGCCCGCGTTGAAAAAAATGAGCGTACCT
TTATCACAACTTTGACCAAGAAAATGGCAGAGGACTTGACCGACTACTTCAAGGAAATGGGTATCAAGGTCAAGTACATG
CACTCGGATATCAAGACCTTGGAACGGACGGAGATTATCCGTGACCTGCGCTTGGGTGTCTTTGATGTCTTGGTCGGAAT
TAACCTGCTCCGTGAAGGAATTGACGTTCCTGAAGTGAGCCTCGTAGCTATTCTCGATGCTGATAAGGAAGGTTTCCTTC
GCAACGAACGTGGACTCATCCAGACTATTGGACGTGCTGCTCGTAACAGTGAAGGCCATGTCATCATGTATGCAGACACG
GTTACCCAGTCTATGCAACGTGCTATCGATGAAACTGCCCGCCGTCGGAAAATTCAGATGACCTATAATGAAGAGCATGA
TATCGTACCACAGACAATCAAGAAAGAAATCCGTGACCTGATTGCCGTGACCAAGGCAGTTGCTAAGGAAGAGGACAAGG
AAGTCGACATCAATAGCCTCAACAAACAAGAGCGCAAGGAACTCGTCAAGAAACTAGAAAAACAAATGCAAGAAGCCGTC
GAAGTGCTTGACTTTGAACTGGCGGCTCAGATTCGTGATATGATGTTGGAAGTCAAGGTCTTGGATTAG

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(626-659)

Type III restriction enzyme, res subunit (ResIII)

(17-143)

Ultra-violet resistance protein B (UvrB)

(556-598)

Helicase conserved C-terminal domain (Helicase_C)

(443-549)

UvrB interaction domain (UvrB_inter)

(164-254)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

99.547

100

0.995
  uvrB Streptococcus pneumoniae D39

99.547

100

0.995
  uvrB Streptococcus pneumoniae TIGR4

99.396

100

0.994