Detailed information NTG0795592

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: PYH56_RS04665
• Genome accession: NZ_CP118820
• Coordinates: 991592..992638 (+)
• Length: 348 a.a.
• NCBI ID: WP_002447441.1
• Uniprot ID: -
• Organism: Staphylococcus epidermidis strain 7057
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 986592..997638

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PYH56_RS04640 (PYH56_04640)	-	987732..988268 (+)	537	WP_162154624.1	hypothetical protein	-
PYH56_RS04645 (PYH56_04645)	-	988420..989406 (-)	987	WP_002447445.1	aromatic acid exporter family protein	-
PYH56_RS04650 (PYH56_04650)	map	989580..990335 (+)	756	WP_162154623.1	type I methionyl aminopeptidase	-
PYH56_RS04655 (PYH56_04655)	-	990493..990879 (+)	387	WP_002495657.1	hypothetical protein	-
PYH56_RS04660 (PYH56_04660)	liaF	990894..991595 (+)	702	WP_002447442.1	cell wall-active antibiotics response protein LiaF	-
PYH56_RS04665 (PYH56_04665)	vraS	991592..992638 (+)	1047	WP_002447441.1	sensor histidine kinase	Regulator
PYH56_RS04670 (PYH56_04670)	vraR	992628..993257 (+)	630	WP_002473914.1	two-component system response regulator VraR	Regulator
PYH56_RS04675 (PYH56_04675)	-	993314..994492 (-)	1179	WP_002487362.1	YihY/virulence factor BrkB family protein	-
PYH56_RS04680 (PYH56_04680)	-	994898..995182 (-)	285	WP_002447438.1	YtxH domain-containing protein	-
PYH56_RS04685 (PYH56_04685)	-	995190..995654 (-)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
PYH56_RS04690 (PYH56_04690)	-	995796..996011 (+)	216	WP_001830421.1	DUF1128 domain-containing protein	-
PYH56_RS04695 (PYH56_04695)	-	996013..997254 (+)	1242	WP_162154621.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40114.53 Da
• Isoelectric Point: 5.8512

>NTDB_id=795592 PYH56_RS04665 WP_002447441.1 991592..992638(+) (vraS) [Staphylococcus epidermidis strain 7057]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVFLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVLHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=795592 PYH56_RS04665 WP_002447441.1 991592..992638(+) (vraS) [Staphylococcus epidermidis strain 7057]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAAGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATAGTTTTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCC
CAAATAGAAAGATCAATAGAAGGACAAACAGTGGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAGAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAGCGACTTGCTAGGGAATTGCATGATTCTGTTAGC
CAACAATTATTTGCTGCGAGCATGATGCTATCAGCAATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTGTTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTCTAGGTGAAGGTATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTTTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGTATTGAAGATCATTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACGAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GATTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTAAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	92.442	98.851	0.914