Detailed information    

insolico Bioinformatically predicted

Overview

Name   comW   Type   Regulator
Locus tag   Q7627_RS00215 Genome accession   NZ_CP131706
Coordinates   35339..35575 (+) Length   78 a.a.
NCBI ID   WP_000939545.1    Uniprot ID   A0A0H2ZMA7
Organism   Streptococcus pneumoniae strain 2018N21-288     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 30339..40575
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7627_RS00205 (Q7627_00205) - 33968..34177 (+) 210 Protein_34 transposase -
  Q7627_RS00210 (Q7627_00210) - 34212..35073 (-) 862 Protein_35 transposase -
  Q7627_RS00215 (Q7627_00215) comW 35339..35575 (+) 237 WP_000939545.1 sigma(X)-activator ComW Regulator
  Q7627_RS00220 (Q7627_00220) - 35806..37092 (+) 1287 WP_000205044.1 adenylosuccinate synthase -
  Q7627_RS00225 (Q7627_00225) tadA 37293..37760 (+) 468 WP_000291870.1 tRNA adenosine(34) deaminase TadA -
  Q7627_RS00235 (Q7627_00235) - 37947..38390 (+) 444 WP_000701992.1 dUTP diphosphatase -
  Q7627_RS00240 (Q7627_00240) - 38392..38907 (+) 516 WP_000691236.1 histidine phosphatase family protein -
  Q7627_RS00245 (Q7627_00245) radA 38921..40282 (+) 1362 WP_078139281.1 DNA repair protein RadA Machinery gene

Sequence

Protein


Download         Length: 78 a.a.        Molecular weight: 9658.13 Da        Isoelectric Point: 6.7051

>NTDB_id=790892 Q7627_RS00215 WP_000939545.1 35339..35575(+) (comW) [Streptococcus pneumoniae strain 2018N21-288]
MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCRKDFIVYHYRVAYRLYLEKLVMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=790892 Q7627_RS00215 WP_000939545.1 35339..35575(+) (comW) [Streptococcus pneumoniae strain 2018N21-288]
ATGTTACAAAAAATTTATGAGCAGATGGCTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTGAGATATGGCATTGGTTGTCGTAAGGATTTTA
TTGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGTTTTATTTCTTGTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2ZMA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

100

100

1
  comW Streptococcus pneumoniae D39

100

100

1
  comW Streptococcus pneumoniae R6

100

100

1
  comW Streptococcus pneumoniae TIGR4

100

100

1
  comW Streptococcus mitis SK321

75.641

100

0.756
  comW Streptococcus mitis NCTC 12261

75.325

98.718

0.744