Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   MTP06_RS17940 Genome accession   NZ_AP025692
Coordinates   4107481..4108152 (+) Length   223 a.a.
NCBI ID   WP_030308132.1    Uniprot ID   A0ABR4S8R3
Organism   Streptomyces sp. PLM4     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4102481..4113152
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MTP06_RS17915 (MTP06_36110) mppP 4103091..4104221 (+) 1131 WP_234344630.1 enduracididine biosynthesis enzyme MppP -
  MTP06_RS17920 (MTP06_36120) - 4104218..4105438 (+) 1221 WP_049978122.1 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme -
  MTP06_RS17925 (MTP06_36130) mppR 4105432..4106274 (+) 843 WP_049978121.1 enduracididine biosynthesis enzyme MppR -
  MTP06_RS17930 (MTP06_36140) - 4106298..4107254 (+) 957 WP_078842881.1 winged helix-turn-helix domain-containing protein -
  MTP06_RS17935 (MTP06_36150) - 4107251..4107460 (+) 210 WP_030308134.1 MbtH family protein -
  MTP06_RS17940 (MTP06_36160) vraR 4107481..4108152 (+) 672 WP_030308132.1 response regulator transcription factor Regulator
  MTP06_RS17945 (MTP06_36170) - 4108235..4109419 (+) 1185 WP_067418162.1 histidine kinase -
  MTP06_RS17950 (MTP06_36180) - 4109536..4109937 (+) 402 WP_030308128.1 hypothetical protein -
  MTP06_RS17955 (MTP06_36190) - 4110028..4110930 (+) 903 WP_248495548.1 ABC transporter ATP-binding protein -
  MTP06_RS17960 (MTP06_36200) - 4110927..4112543 (+) 1617 WP_248495550.1 ABC transporter permease -
  MTP06_RS17965 (MTP06_36210) - 4112591..4112773 (+) 183 WP_030308122.1 hypothetical protein -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 24232.97 Da        Isoelectric Point: 9.5518

>NTDB_id=78378 MTP06_RS17940 WP_030308132.1 4107481..4108152(+) (vraR) [Streptomyces sp. PLM4]
MTVKLVLVDDQEMVRRGMRVIFDNQQGMEVVGEAADGVEAVEVARRLQPDVVLADIRMPRMDGLEVVRRLAGPQAPEPRP
KVIVVTTFDLDEYVYPALRNGASGFLLKRSGPALLVEAVRAAMAGDSLISPSVTVRLLRHVTGNRAPGDPEPRAEALTER
EGEIAALVAEGGTNADIAAELFISPGTVKTHVAAIQRKFGVRNRVGIAVRAFERGYTFSRRPK

Nucleotide


Download         Length: 672 bp        

>NTDB_id=78378 MTP06_RS17940 WP_030308132.1 4107481..4108152(+) (vraR) [Streptomyces sp. PLM4]
ATGACGGTGAAACTGGTGCTCGTCGACGATCAGGAGATGGTCCGGCGGGGTATGCGGGTCATCTTCGACAACCAGCAGGG
CATGGAGGTGGTCGGCGAGGCGGCCGACGGGGTGGAGGCGGTGGAGGTCGCCCGCCGCCTCCAGCCGGACGTGGTCCTGG
CGGACATCAGGATGCCCCGGATGGACGGCCTGGAGGTGGTCCGGCGGCTGGCGGGACCCCAGGCGCCCGAACCGCGGCCC
AAGGTCATCGTCGTCACCACCTTCGACCTCGACGAGTACGTGTACCCGGCGCTGCGCAACGGCGCCTCCGGGTTCCTGCT
GAAGCGCTCGGGCCCCGCCCTGCTGGTGGAGGCGGTCCGCGCCGCCATGGCCGGGGACAGCCTGATCAGCCCGTCCGTCA
CGGTGCGGCTGCTGCGGCACGTCACCGGCAACCGGGCGCCGGGCGACCCGGAGCCCCGCGCGGAGGCGCTGACCGAGCGG
GAGGGCGAGATCGCCGCGCTGGTCGCCGAAGGCGGCACCAACGCCGACATCGCCGCCGAACTCTTCATCTCCCCGGGCAC
GGTCAAGACCCATGTGGCCGCCATCCAGCGGAAGTTCGGGGTGCGGAACCGGGTCGGCATCGCCGTCCGGGCCTTCGAGC
GCGGATACACCTTCAGCCGCCGCCCGAAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-120)

Bacterial regulatory proteins, luxR family (GerE)

(156-210)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.605

96.413

0.372

Multiple sequence alignment