Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   PP185_RS18690 Genome accession   NZ_CP116892
Coordinates   3581276..3582514 (-) Length   412 a.a.
NCBI ID   WP_000990715.1    Uniprot ID   Q81WQ3
Organism   Bacillus anthracis strain AN18-416_2     
Function   unknown (predicted from homology)   
Unclear

Genomic Context

Location: 3576276..3587514
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PP185_RS18665 (PP185_18670) spoVS 3576358..3576618 (-) 261 WP_000404341.1 stage V sporulation protein SpoVS -
  PP185_RS18670 (PP185_18675) - 3576768..3577562 (-) 795 WP_001221090.1 TIGR00282 family metallophosphoesterase -
  PP185_RS18675 (PP185_18680) rny 3577728..3579290 (-) 1563 WP_000099773.1 ribonuclease Y -
  PP185_RS18680 (PP185_18685) - 3579773..3580195 (-) 423 Protein_3639 DNA recombination/repair protein RecA -
  PP185_RS18685 (PP185_18690) recA 3580523..3581131 (-) 609 Protein_3640 recombinase RecA -
  PP185_RS18690 (PP185_18695) cinA 3581276..3582514 (-) 1239 WP_000990715.1 competence/damage-inducible protein CinA Machinery gene
  PP185_RS18695 (PP185_18700) pgsA 3582535..3583113 (-) 579 WP_001052973.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PP185_RS18700 (PP185_18705) - 3583177..3584088 (-) 912 WP_000137488.1 helix-turn-helix domain-containing protein -
  PP185_RS18705 (PP185_18710) - 3584110..3584895 (-) 786 WP_000574107.1 DUF3388 domain-containing protein -
  PP185_RS18710 (PP185_18715) - 3585035..3585283 (-) 249 WP_000114454.1 DUF3243 domain-containing protein -
  PP185_RS18715 (PP185_18720) - 3585359..3586072 (-) 714 WP_000759617.1 SDR family oxidoreductase -
  PP185_RS18720 (PP185_18725) - 3586176..3587462 (-) 1287 WP_000411960.1 pitrilysin family protein -

Sequence

Protein


Download         Length: 412 a.a.        Molecular weight: 45309.55 Da        Isoelectric Point: 4.9485

>NTDB_id=780884 PP185_RS18690 WP_000990715.1 3581276..3582514(-) (cinA) [Bacillus anthracis strain AN18-416_2]
MNAEIIAVGTELLLGQIANTNAQFLSEKLASIGINVYYHTVVGDNNKRLQQAIEVAEERADMLIFTGGLGPTKDDLTKET
IASSLAEELVYDEKALASISDYFKRTGREFTENNKKQALVLDGATVFANDHGMAPGMGLNKNGKVYILLPGPPKEMKPMY
VSYVEPFLRNFTTGENIYSRVLRFFGIGESQLEVKVQDLIDGQTNPTIAPLANDGEVTLRLTAKHQNVDEAEKLIQHVED
LILERVGGFFYGYDQEFLHDKAIVLLKKKGLTLACAESLTGGLFGNQVTESAGVSSVFKGGVICYHNDVKQHVLHVPEEV
LFTDGAVSKECARYLAENVKELLEADIGISFTGVAGPDASEHKEPGTVFVGLAIKDEPTVVFPLNLSGSRQQIRERSAKY
GFYHLYKKLEEI

Nucleotide


Download         Length: 1239 bp        

>NTDB_id=780884 PP185_RS18690 WP_000990715.1 3581276..3582514(-) (cinA) [Bacillus anthracis strain AN18-416_2]
ATGAATGCGGAGATTATTGCGGTTGGAACGGAATTATTACTTGGACAAATTGCAAATACAAATGCCCAGTTTTTATCTGA
AAAGTTAGCTTCAATTGGAATTAACGTGTACTACCATACTGTAGTTGGGGATAATAACAAGCGACTGCAGCAGGCGATTG
AAGTTGCAGAGGAACGTGCGGATATGCTCATTTTCACAGGTGGATTAGGACCGACGAAAGATGATTTAACGAAGGAAACA
ATAGCGTCTAGCTTAGCGGAAGAGCTTGTATATGATGAAAAGGCATTAGCATCAATAAGCGATTACTTTAAGCGAACAGG
TCGAGAGTTCACGGAGAATAATAAAAAGCAGGCGCTCGTTTTGGATGGAGCAACTGTATTTGCAAATGATCACGGTATGG
CACCTGGTATGGGATTAAATAAGAACGGAAAAGTTTATATTTTATTACCAGGACCACCGAAAGAAATGAAGCCAATGTAT
GTAAGTTATGTGGAGCCTTTTTTACGTAACTTTACAACAGGAGAAAACATTTATTCTCGCGTGCTTCGCTTTTTCGGAAT
TGGGGAATCTCAATTAGAGGTGAAAGTTCAAGATTTAATTGATGGACAAACGAATCCGACAATTGCCCCGCTTGCGAATG
ATGGAGAAGTGACATTACGTTTAACTGCTAAACATCAAAATGTTGATGAAGCAGAGAAACTCATTCAGCATGTGGAAGAT
TTGATTTTAGAAAGAGTAGGAGGATTTTTCTACGGGTATGACCAAGAGTTTCTGCATGATAAGGCGATAGTGTTATTGAA
GAAAAAAGGATTAACTTTAGCGTGTGCGGAAAGTTTAACAGGTGGTCTCTTCGGTAATCAAGTAACAGAAAGTGCTGGTG
TGTCTTCCGTATTTAAAGGTGGTGTCATTTGTTATCATAATGACGTGAAGCAGCATGTTTTACATGTACCTGAGGAAGTG
TTGTTTACTGACGGTGCAGTTAGTAAAGAATGTGCTCGTTATCTTGCTGAAAATGTTAAAGAATTATTAGAAGCGGATAT
CGGGATTAGTTTCACTGGGGTAGCAGGACCGGATGCTTCAGAACATAAAGAACCGGGAACAGTATTTGTTGGATTGGCGA
TTAAAGATGAACCAACTGTAGTCTTTCCTCTTAATTTAAGTGGAAGTCGCCAACAAATTAGAGAACGCTCAGCAAAATAT
GGATTTTATCATTTATATAAAAAGCTAGAAGAAATATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(179-252)

Competence-damaged protein (CinA)

(258-408)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q81WQ3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Bacillus subtilis subsp. subtilis str. 168

58.738

100

0.587
  cinA Streptococcus mitis SK321

47.017

100

0.478
  cinA Streptococcus pneumoniae TIGR4

46.778

100

0.476
  cinA Streptococcus pneumoniae Rx1

46.301

100

0.471
  cinA Streptococcus pneumoniae R6

46.301

100

0.471
  cinA Streptococcus pneumoniae D39

46.062

100

0.468
  cinA Streptococcus mitis NCTC 12261

46.062

100

0.468
  cinA Streptococcus mutans UA159

45.567

98.544

0.449
  cinA Streptococcus suis isolate S10

41.27

91.748

0.379