Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   OS912_RS05365 Genome accession   NZ_CP113266
Coordinates   1045708..1046034 (-) Length   108 a.a.
NCBI ID   WP_000738626.1    Uniprot ID   Q8DN88
Organism   Streptococcus pneumoniae strain BC1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1040708..1051034
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OS912_RS05320 (OS912_05325) rnpA 1040735..1041106 (-) 372 WP_000739246.1 ribonuclease P protein component -
  OS912_RS05325 (OS912_05330) - 1041123..1041254 (-) 132 WP_000768904.1 hypothetical protein -
  OS912_RS05330 (OS912_05335) - 1041255..1042445 (-) 1191 WP_000167766.1 acetate kinase -
  OS912_RS05335 (OS912_05340) comYH 1042496..1043449 (-) 954 WP_050212403.1 class I SAM-dependent methyltransferase Machinery gene
  OS912_RS05340 (OS912_05345) - 1043510..1044097 (-) 588 Protein_1034 class I SAM-dependent methyltransferase -
  OS912_RS05345 (OS912_05350) comGG/cglG 1044234..1044644 (-) 411 WP_000265621.1 competence type IV pilus minor pilin ComGG Machinery gene
  OS912_RS05350 (OS912_05355) comGF/cglF 1044622..1045083 (-) 462 WP_268233038.1 competence type IV pilus minor pilin ComGF Machinery gene
  OS912_RS05355 (OS912_05360) comGE/cglE 1045046..1045348 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  OS912_RS05360 (OS912_05365) comGD/cglD 1045311..1045715 (-) 405 WP_000588013.1 competence type IV pilus minor pilin ComGD Machinery gene
  OS912_RS05365 (OS912_05370) comGC/cglC 1045708..1046034 (-) 327 WP_000738626.1 comG operon protein ComGC Machinery gene
  OS912_RS05370 (OS912_05375) comGB/cglB 1046036..1047052 (-) 1017 WP_268233044.1 competence type IV pilus assembly protein ComGB Machinery gene
  OS912_RS05375 (OS912_05380) comGA/cglA/cilD 1047000..1047941 (-) 942 WP_000249550.1 competence type IV pilus ATPase ComGA Machinery gene
  OS912_RS05380 (OS912_05385) - 1048017..1048382 (-) 366 WP_000286415.1 DUF1033 family protein -
  OS912_RS05385 (OS912_05390) - 1048533..1049591 (-) 1059 WP_000649466.1 zinc-dependent alcohol dehydrogenase family protein -
  OS912_RS05390 (OS912_05395) nagA 1049754..1050905 (-) 1152 WP_001134459.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12200.38 Da        Isoelectric Point: 10.1877

>NTDB_id=761416 OS912_RS05365 WP_000738626.1 1045708..1046034(-) (comGC/cglC) [Streptococcus pneumoniae strain BC1]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQA
DGRITEEQAKAYKEYHDKNGGANRKVND

Nucleotide


Download         Length: 327 bp        

>NTDB_id=761416 OS912_RS05365 WP_000738626.1 1045708..1046034(-) (comGC/cglC) [Streptococcus pneumoniae strain BC1]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAAATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTAGAAAAGAATGAAGATGCTAGCCTAAGAAAGTTACAAGCA
GATGGACGCATCACGGAAGAACAGGCTAAAGCTTATAAAGAATACCATGATAAAAATGGAGGAGCAAATCGTAAAGTCAA
TGATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 6Y1H

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae Rx1

100

100

1
  comGC/cglC Streptococcus pneumoniae D39

100

100

1
  comGC/cglC Streptococcus pneumoniae R6

100

100

1
  comGC/cglC Streptococcus pneumoniae TIGR4

99.074

100

0.991
  comGC/cglC Streptococcus mitis SK321

94.444

100

0.944
  comGC/cglC Streptococcus mitis NCTC 12261

92.157

94.444

0.87
  comYC Streptococcus gordonii str. Challis substr. CH1

67.961

95.37

0.648
  comYC Streptococcus mutans UA140

62.745

94.444

0.593
  comYC Streptococcus mutans UA159

62.745

94.444

0.593
  comYC Streptococcus suis isolate S10

70.37

75

0.528
  comGC Lactococcus lactis subsp. cremoris KW2

53.922

94.444

0.509
  comGC Staphylococcus aureus MW2

50

79.63

0.398
  comGC Staphylococcus aureus N315

50

79.63

0.398
  comGC Latilactobacillus sakei subsp. sakei 23K

45.349

79.63

0.361