Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   OS912_RS05370 Genome accession   NZ_CP113266
Coordinates   1046036..1047052 (-) Length   338 a.a.
NCBI ID   WP_268233044.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain BC1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1041036..1052052
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OS912_RS05325 (OS912_05330) - 1041123..1041254 (-) 132 WP_000768904.1 hypothetical protein -
  OS912_RS05330 (OS912_05335) - 1041255..1042445 (-) 1191 WP_000167766.1 acetate kinase -
  OS912_RS05335 (OS912_05340) comYH 1042496..1043449 (-) 954 WP_050212403.1 class I SAM-dependent methyltransferase Machinery gene
  OS912_RS05340 (OS912_05345) - 1043510..1044097 (-) 588 Protein_1034 class I SAM-dependent methyltransferase -
  OS912_RS05345 (OS912_05350) comGG/cglG 1044234..1044644 (-) 411 WP_000265621.1 competence type IV pilus minor pilin ComGG Machinery gene
  OS912_RS05350 (OS912_05355) comGF/cglF 1044622..1045083 (-) 462 WP_268233038.1 competence type IV pilus minor pilin ComGF Machinery gene
  OS912_RS05355 (OS912_05360) comGE/cglE 1045046..1045348 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  OS912_RS05360 (OS912_05365) comGD/cglD 1045311..1045715 (-) 405 WP_000588013.1 competence type IV pilus minor pilin ComGD Machinery gene
  OS912_RS05365 (OS912_05370) comGC/cglC 1045708..1046034 (-) 327 WP_000738626.1 comG operon protein ComGC Machinery gene
  OS912_RS05370 (OS912_05375) comGB/cglB 1046036..1047052 (-) 1017 WP_268233044.1 competence type IV pilus assembly protein ComGB Machinery gene
  OS912_RS05375 (OS912_05380) comGA/cglA/cilD 1047000..1047941 (-) 942 WP_000249550.1 competence type IV pilus ATPase ComGA Machinery gene
  OS912_RS05380 (OS912_05385) - 1048017..1048382 (-) 366 WP_000286415.1 DUF1033 family protein -
  OS912_RS05385 (OS912_05390) - 1048533..1049591 (-) 1059 WP_000649466.1 zinc-dependent alcohol dehydrogenase family protein -
  OS912_RS05390 (OS912_05395) nagA 1049754..1050905 (-) 1152 WP_001134459.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38508.60 Da        Isoelectric Point: 9.6162

>NTDB_id=761417 OS912_RS05370 WP_268233044.1 1046036..1047052(-) (comGB/cglB) [Streptococcus pneumoniae strain BC1]
MDISQVFRLRRKKLATAKQKNIIILFNNLFSSGFHLVETISFLDRSALLDKQCVTQMRAGLSQGKSFSEMMESLGCSSAI
VTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLFFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQGMELTQIFQMMQEQGSQLFKEI
GQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=761417 OS912_RS05370 WP_268233044.1 1046036..1047052(-) (comGB/cglB) [Streptococcus pneumoniae strain BC1]
ATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAAGCAAAAAAATATCATCATCCTATTTAA
CAATCTCTTTTCTAGCGGTTTTCATCTGGTGGAGACCATCTCCTTTTTAGATAGGAGTGCTTTGTTGGACAAGCAGTGTG
TGACCCAGATGCGTGCGGGCTTGTCTCAGGGGAAATCATTCTCAGAAATGATGGAAAGTTTGGGATGTTCAAGTGCTATT
GTCACTCAGTTATCCCTAGCTGAAGTCCATGGCAATCTCCACCTGAGTTTGGGAAAGATAGAAGAGTATCTAGACAATCT
GGCCAAGGTCAAGAAAAAATTAATTGAAGTAGCGACCTATCCTTTGATTTTGCTGTTTTTTCTTCTCTTAATTATGCTGG
GGCTACGGAATTACCTGCTCCCACAACTGGATAGTAGCAATATTGCCACCCGAATTATCGGTAATCTGCCACAAATTTTT
CTAGGCATGGTAGGGCTTGTTTCCGTGCTTGCCCTTTTAGCACTAACTTTTTATAAAAGAAGTTCTAAGATGAGTGTCTT
TTCTATCTTAGCACGCCTTCCCTTTATTGGAATCTTTGTGCAGACCTACTTGACAGCCTATTATGCACGTGAATGGGGGA
ATATGATTTCACAGGGAATGGAGCTGACGCAGATTTTTCAAATGATGCAGGAACAAGGTTCCCAGCTCTTTAAAGAAATC
GGTCAAGATCTGGCTCAAACCCTGAAAAATGGCCGTGAATTTTCTCAGACGATAGGAACCTATCCTTTCTTTAGGAAGGA
ATTGAGTCTCATCATAGAGTATGGGGAAGTTAAGTCCAAGCTGGGTAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGCCTTTTTTACCCGAGTCAACCGCACCATGAATTTGGTGCAGCCACTGGTTTTTATCTTTGTGGCACTGATTATCGTT
TTACTTTATGCGGCAATGCTCATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(26-141)

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus pneumoniae Rx1

98.521

100

0.985
  comGB/cglB Streptococcus pneumoniae D39

98.521

100

0.985
  comGB/cglB Streptococcus pneumoniae R6

98.521

100

0.985
  comGB/cglB Streptococcus pneumoniae TIGR4

98.521

100

0.985
  comGB/cglB Streptococcus mitis SK321

94.675

100

0.947
  comGB/cglB Streptococcus mitis NCTC 12261

94.379

100

0.944
  comYB Streptococcus gordonii str. Challis substr. CH1

70.833

99.408

0.704
  comYB Streptococcus mutans UA140

58.176

94.083

0.547
  comYB Streptococcus mutans UA159

58.176

94.083

0.547
  comGB Lactococcus lactis subsp. cremoris KW2

50.898

98.817

0.503