Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   OS912_RS05355 Genome accession   NZ_CP113266
Coordinates   1045046..1045348 (-) Length   100 a.a.
NCBI ID   WP_000413382.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain BC1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1040046..1050348
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OS912_RS05320 (OS912_05325) rnpA 1040735..1041106 (-) 372 WP_000739246.1 ribonuclease P protein component -
  OS912_RS05325 (OS912_05330) - 1041123..1041254 (-) 132 WP_000768904.1 hypothetical protein -
  OS912_RS05330 (OS912_05335) - 1041255..1042445 (-) 1191 WP_000167766.1 acetate kinase -
  OS912_RS05335 (OS912_05340) comYH 1042496..1043449 (-) 954 WP_050212403.1 class I SAM-dependent methyltransferase Machinery gene
  OS912_RS05340 (OS912_05345) - 1043510..1044097 (-) 588 Protein_1034 class I SAM-dependent methyltransferase -
  OS912_RS05345 (OS912_05350) comGG/cglG 1044234..1044644 (-) 411 WP_000265621.1 competence type IV pilus minor pilin ComGG Machinery gene
  OS912_RS05350 (OS912_05355) comGF/cglF 1044622..1045083 (-) 462 WP_268233038.1 competence type IV pilus minor pilin ComGF Machinery gene
  OS912_RS05355 (OS912_05360) comGE/cglE 1045046..1045348 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  OS912_RS05360 (OS912_05365) comGD/cglD 1045311..1045715 (-) 405 WP_000588013.1 competence type IV pilus minor pilin ComGD Machinery gene
  OS912_RS05365 (OS912_05370) comGC/cglC 1045708..1046034 (-) 327 WP_000738626.1 comG operon protein ComGC Machinery gene
  OS912_RS05370 (OS912_05375) comGB/cglB 1046036..1047052 (-) 1017 WP_268233044.1 competence type IV pilus assembly protein ComGB Machinery gene
  OS912_RS05375 (OS912_05380) comGA/cglA/cilD 1047000..1047941 (-) 942 WP_000249550.1 competence type IV pilus ATPase ComGA Machinery gene
  OS912_RS05380 (OS912_05385) - 1048017..1048382 (-) 366 WP_000286415.1 DUF1033 family protein -
  OS912_RS05385 (OS912_05390) - 1048533..1049591 (-) 1059 WP_000649466.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11108.08 Da        Isoelectric Point: 9.7273

>NTDB_id=761414 OS912_RS05355 WP_000413382.1 1045046..1045348(-) (comGE/cglE) [Streptococcus pneumoniae strain BC1]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=761414 OS912_RS05355 WP_000413382.1 1045046..1045348(-) (comGE/cglE) [Streptococcus pneumoniae strain BC1]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCCTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

100

100

1
  comGE/cglE Streptococcus pneumoniae D39

100

100

1
  comGE/cglE Streptococcus pneumoniae R6

100

100

1
  comGE/cglE Streptococcus pneumoniae TIGR4

100

100

1
  comGE/cglE Streptococcus mitis NCTC 12261

98

100

0.98
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

44.444

90

0.4
  comYE Streptococcus mutans UA159

44.444

90

0.4