Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   OS912_RS05335 Genome accession   NZ_CP113266
Coordinates   1042496..1043449 (-) Length   317 a.a.
NCBI ID   WP_050212403.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain BC1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1037496..1048449
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OS912_RS05305 (OS912_05310) - 1038257..1038880 (-) 624 WP_000932655.1 hypothetical protein -
  OS912_RS05310 (OS912_05315) jag 1038931..1039917 (-) 987 WP_268233037.1 RNA-binding cell elongation regulator Jag/EloR -
  OS912_RS05315 (OS912_05320) - 1039936..1040760 (-) 825 WP_000727904.1 membrane protein insertase YidC -
  OS912_RS05320 (OS912_05325) rnpA 1040735..1041106 (-) 372 WP_000739246.1 ribonuclease P protein component -
  OS912_RS05325 (OS912_05330) - 1041123..1041254 (-) 132 WP_000768904.1 hypothetical protein -
  OS912_RS05330 (OS912_05335) - 1041255..1042445 (-) 1191 WP_000167766.1 acetate kinase -
  OS912_RS05335 (OS912_05340) comYH 1042496..1043449 (-) 954 WP_050212403.1 class I SAM-dependent methyltransferase Machinery gene
  OS912_RS05340 (OS912_05345) - 1043510..1044097 (-) 588 Protein_1034 class I SAM-dependent methyltransferase -
  OS912_RS05345 (OS912_05350) comGG/cglG 1044234..1044644 (-) 411 WP_000265621.1 competence type IV pilus minor pilin ComGG Machinery gene
  OS912_RS05350 (OS912_05355) comGF/cglF 1044622..1045083 (-) 462 WP_268233038.1 competence type IV pilus minor pilin ComGF Machinery gene
  OS912_RS05355 (OS912_05360) comGE/cglE 1045046..1045348 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  OS912_RS05360 (OS912_05365) comGD/cglD 1045311..1045715 (-) 405 WP_000588013.1 competence type IV pilus minor pilin ComGD Machinery gene
  OS912_RS05365 (OS912_05370) comGC/cglC 1045708..1046034 (-) 327 WP_000738626.1 comG operon protein ComGC Machinery gene
  OS912_RS05370 (OS912_05375) comGB/cglB 1046036..1047052 (-) 1017 WP_268233044.1 competence type IV pilus assembly protein ComGB Machinery gene
  OS912_RS05375 (OS912_05380) comGA/cglA/cilD 1047000..1047941 (-) 942 WP_000249550.1 competence type IV pilus ATPase ComGA Machinery gene
  OS912_RS05380 (OS912_05385) - 1048017..1048382 (-) 366 WP_000286415.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35702.92 Da        Isoelectric Point: 4.2706

>NTDB_id=761411 OS912_RS05335 WP_050212403.1 1042496..1043449(-) (comYH) [Streptococcus pneumoniae strain BC1]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEMDALLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFILQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=761411 OS912_RS05335 WP_050212403.1 1042496..1043449(-) (comYH) [Streptococcus pneumoniae strain BC1]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAACAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC
AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCGGATGCTATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAATGGATGCTTTGCTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTTGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGCTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGAATGGCTGAAAGAAGAGGCGAGTCTGGTTGCTATGATTAGTCTGCCTGAAAATCTCTTTGCTAA
TGCCAAACAATCTAAGACTATTTTTATCTTACAGAAGAAAAATGAAATAGCAGTAGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

53.994

98.738

0.533
  comYH Streptococcus mutans UA159

53.674

98.738

0.53