Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   LDO09_RS08435 Genome accession   NZ_AP024926
Coordinates   1576796..1578577 (+) Length   593 a.a.
NCBI ID   WP_223968662.1    Uniprot ID   -
Organism   Thermus thermophilus strain AA1-1     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1571796..1583577
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LDO09_RS08400 (TthAA11_16610) tilS 1572284..1573807 (+) 1524 WP_143586354.1 tRNA lysidine(34) synthetase TilS -
  LDO09_RS08410 (TthAA11_16620) - 1573949..1574389 (-) 441 WP_143586356.1 hypothetical protein -
  LDO09_RS08415 (TthAA11_16630) - 1574386..1574781 (-) 396 WP_143586359.1 alpha/beta hydrolase -
  LDO09_RS08420 (TthAA11_16640) - 1574778..1575410 (-) 633 WP_165739092.1 alpha/beta hydrolase -
  LDO09_RS08425 (TthAA11_16650) - 1575432..1575845 (+) 414 WP_143586361.1 PaaI family thioesterase -
  LDO09_RS08430 (TthAA11_16660) - 1575819..1576781 (-) 963 WP_143586363.1 membrane dipeptidase -
  LDO09_RS08435 (TthAA11_16670) uvrC 1576796..1578577 (+) 1782 WP_223968662.1 excinuclease ABC subunit UvrC Machinery gene
  LDO09_RS08440 (TthAA11_16680) - 1578628..1579551 (-) 924 WP_223968665.1 ribose-phosphate pyrophosphokinase -
  LDO09_RS08445 (TthAA11_16690) mtnN 1579566..1580228 (-) 663 WP_143586367.1 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase -
  LDO09_RS08450 (TthAA11_16700) luxS 1580225..1580692 (-) 468 WP_143586369.1 S-ribosylhomocysteine lyase Regulator
  LDO09_RS08455 (TthAA11_16710) - 1580731..1581558 (+) 828 WP_143586371.1 KaiC domain-containing protein -
  LDO09_RS08460 (TthAA11_16720) - 1581603..1582214 (+) 612 WP_014510710.1 circadian clock protein KaiC -

Sequence

Protein


Download         Length: 593 a.a.        Molecular weight: 67156.89 Da        Isoelectric Point: 9.8340

>NTDB_id=75868 LDO09_RS08435 WP_223968662.1 1576796..1578577(+) (uvrC) [Thermus thermophilus strain AA1-1]
MGGVRAQDLPPLPETPGVYLWKRGEEVLYVGKAKSLRARVKSYFHAEGKARRIAEEATGLDFIATRDEVEALLLEANLIK
AHRPPYNVLLKDDKHYPFLKLTNEPFPTLLVVRRVEEDGAKYYGPFPEAGALRRIKTLIDRLFPLRKNSGYPMKKRRYPC
LNYSMGRCLAPCVGKADPEAYQEVVRQVEAVLEGRVDGLLQELEAKMREAASRLEFERAAEIRDQMEALRAFFSTDQQAF
DPEMGDLDFLGLARSGALAVVQLYQVRSGRILGRISRVVEKEEATDEEILWAFLRDHYLEASPLPPLVLLPFPLEDLESL
AELLKRRAGRKVELRVPKKGEKARLLELAERNARLALETELKLRERRGEHPALKALQDLLGLPARPWRLEGYDISHLQGQ
ARVFSIAVFEGGRPKRQEYRKMRLKAGNDDYAAMEEGVFRRYTGSLKDLPLPDLLLIDGGVGQVRAAARALERAGLRLPL
VGLAKGEEVLVTPEGRELRLPLTHPALQLLIHLRDEAHQNGLRYHRKRRSEELFRVLQGIPGIGEKRRRLLLERYGGLRA
LKEAPLEELARLPGMSLEAARALKAALAKEEPA

Nucleotide


Download         Length: 1782 bp        

>NTDB_id=75868 LDO09_RS08435 WP_223968662.1 1576796..1578577(+) (uvrC) [Thermus thermophilus strain AA1-1]
ATGGGGGGCGTGCGGGCCCAAGACCTCCCTCCCCTCCCCGAGACCCCCGGGGTCTACCTGTGGAAGCGGGGGGAGGAGGT
GCTCTACGTGGGCAAGGCCAAGAGCCTCCGCGCCCGGGTGAAAAGCTACTTCCACGCCGAGGGCAAGGCCCGGCGCATCG
CCGAGGAGGCCACAGGCCTGGACTTCATCGCCACCCGGGACGAGGTGGAGGCCCTCCTCCTCGAGGCCAACCTCATCAAG
GCCCACCGCCCCCCCTACAACGTCCTCCTCAAGGACGACAAGCACTACCCCTTCCTTAAGCTCACCAACGAGCCCTTCCC
CACCCTCCTCGTGGTGCGCCGGGTGGAGGAGGACGGGGCCAAGTACTACGGCCCCTTCCCCGAGGCGGGGGCGCTTCGCC
GCATCAAGACCCTCATAGACCGCCTCTTCCCCTTGCGCAAGAACTCGGGCTACCCCATGAAGAAAAGGCGCTACCCCTGC
CTGAACTACAGCATGGGCCGCTGCCTCGCCCCTTGCGTGGGGAAGGCGGACCCAGAGGCCTACCAGGAGGTGGTGCGCCA
GGTGGAGGCGGTCCTCGAGGGCCGGGTGGACGGGCTCCTTCAGGAGCTCGAGGCCAAGATGCGGGAGGCGGCGAGCAGGC
TTGAGTTTGAGCGGGCGGCGGAGATCCGCGACCAGATGGAGGCCCTAAGGGCCTTCTTCTCCACGGACCAGCAGGCCTTT
GACCCGGAGATGGGGGACCTGGACTTCCTGGGCCTCGCCCGCTCCGGGGCCCTCGCCGTGGTGCAGCTCTACCAGGTGCG
CTCCGGGCGGATCCTCGGCCGCATCAGCCGCGTGGTGGAGAAGGAGGAGGCCACGGACGAGGAAATCCTCTGGGCCTTCC
TCCGGGACCACTACCTGGAGGCCTCCCCCCTCCCCCCCCTCGTCCTCCTACCCTTCCCCCTGGAGGACCTGGAAAGCCTC
GCCGAGCTCCTTAAGCGCCGCGCGGGGCGGAAGGTGGAGCTAAGGGTGCCGAAGAAGGGGGAGAAGGCGAGGCTCTTGGA
GCTCGCCGAAAGGAACGCCCGCCTCGCCCTGGAGACCGAGCTCAAGCTCCGGGAAAGGCGGGGGGAGCACCCCGCCCTCA
AGGCCCTCCAGGACCTCCTGGGGCTTCCCGCCCGCCCCTGGCGCCTCGAGGGCTACGACATAAGCCACCTCCAAGGCCAG
GCCCGGGTCTTCTCCATCGCCGTCTTTGAGGGGGGAAGGCCCAAGCGGCAGGAGTACCGCAAGATGCGCCTCAAGGCGGG
GAACGACGACTACGCCGCCATGGAGGAAGGGGTCTTCCGCCGCTACACGGGAAGCCTCAAGGACCTTCCCCTCCCCGACC
TCCTCCTCATTGACGGGGGAGTGGGCCAGGTGCGGGCGGCAGCAAGGGCCCTGGAGCGGGCGGGCCTTAGGCTTCCCCTG
GTGGGCCTCGCCAAGGGGGAGGAGGTCCTGGTCACGCCGGAAGGGCGGGAGCTCCGCCTCCCCCTCACCCACCCGGCCCT
TCAGCTCCTCATCCACCTCCGGGACGAGGCCCACCAAAACGGCCTCCGTTACCACCGGAAGCGGCGGAGCGAGGAGCTTT
TCCGGGTCCTCCAGGGCATCCCCGGGATCGGGGAGAAAAGGAGGCGGCTCCTTTTGGAGCGCTACGGGGGGCTAAGGGCC
CTTAAGGAGGCCCCCCTGGAGGAGCTCGCCCGGCTTCCCGGGATGAGCCTCGAGGCCGCCCGGGCCCTCAAGGCGGCCCT
GGCCAAGGAGGAGCCCGCCTGA

Domains

Predicted by InterProScan.

Helix-hairpin-helix domain (HHH_5)

(534-588)

UvrB/uvrC motif (UVR)

(199-231)

GIY-YIG catalytic domain (GIY-YIG)

(17-87)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(377-519)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae R6

36.395

99.157

0.361
  uvrC Streptococcus pneumoniae D39

36.395

99.157

0.361
  uvrC Streptococcus pneumoniae TIGR4

36.395

99.157

0.361

Multiple sequence alignment