Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   FLY91_RS04860 Genome accession   NZ_AP024560
Coordinates   1025711..1026301 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain NIPH17_0020     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1020711..1031301
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FLY91_RS04830 emrD 1021193..1022377 (-) 1185 WP_060621156.1 multidrug efflux MFS transporter EmrD -
  FLY91_RS04835 ysdE 1022459..1022533 (+) 75 WP_211180519.1 protein YsdE -
  FLY91_RS04840 tisB 1022796..1022885 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  FLY91_RS04845 ivbL 1023450..1023548 (+) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  FLY91_RS04850 ilvB 1023654..1025342 (+) 1689 WP_000168480.1 acetolactate synthase large subunit -
  FLY91_RS04855 ilvN 1025346..1025636 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  FLY91_RS04860 letA 1025711..1026301 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  FLY91_RS04865 uhpB 1026301..1027803 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  FLY91_RS04870 uhpC 1027813..1029132 (+) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  FLY91_RS04875 uhpT 1029270..1030661 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=73225 FLY91_RS04860 WP_000633668.1 1025711..1026301(+) (letA) [Escherichia coli strain NIPH17_0020]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=73225 FLY91_RS04860 WP_000633668.1 1025711..1026301(+) (letA) [Escherichia coli strain NIPH17_0020]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGCGAACGGCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCGCCGAAAACGGTGCACGTCCATCGCGCCAACCTGATGGAAAAACTGGGTGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378

Multiple sequence alignment