Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   NX050_RS12715 Genome accession   NZ_CP103456
Coordinates   2347424..2348674 (-) Length   416 a.a.
NCBI ID   WP_003231847.1    Uniprot ID   A0A199WIX6
Organism   Bacillus subtilis strain PN176 (HK176)     
Function   unknown (predicted from homology)   
Unclear

Genomic Context

Location: 2342424..2353674
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NX050_RS12700 (NX050_12700) rny 2343025..2344587 (-) 1563 WP_003221010.1 ribonuclease Y -
  NX050_RS12705 (NX050_12705) pbpX 2344863..2346038 (-) 1176 WP_014479815.1 serine hydrolase -
  NX050_RS12710 (NX050_12710) recA 2346205..2347251 (-) 1047 WP_003245789.1 recombinase RecA Machinery gene
  NX050_RS12715 (NX050_12715) cinA 2347424..2348674 (-) 1251 WP_003231847.1 competence/damage-inducible protein A Machinery gene
  NX050_RS12720 (NX050_12720) pgsA 2348692..2349273 (-) 582 WP_014479814.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NX050_RS12725 (NX050_12725) rodZ 2349323..2350189 (-) 867 WP_206697876.1 RodZ family helix-turn-helix domain-containing protein -
  NX050_RS12730 (NX050_12730) - 2350256..2351047 (-) 792 WP_003220998.1 YmfK family protein -
  NX050_RS12735 (NX050_12735) ymfJ 2351177..2351434 (-) 258 WP_003245199.1 DUF3243 domain-containing protein -
  NX050_RS12740 (NX050_12740) ymfI 2351515..2352243 (-) 729 WP_003244676.1 elongation factor P 5-aminopentanone reductase -
  NX050_RS12745 (NX050_12745) yfmH 2352298..2353584 (-) 1287 WP_003244823.1 EF-P 5-aminopentanol modification-associated protein YfmH -

Sequence

Protein


Download         Length: 416 a.a.        Molecular weight: 45537.85 Da        Isoelectric Point: 5.3737

>NTDB_id=722888 NX050_RS12715 WP_003231847.1 2347424..2348674(-) (cinA) [Bacillus subtilis strain PN176 (HK176)]
MEFPKKAEIIAVGSELLLGQIANTNAQFISKQLAEIGVNVFYHTAVGDNPERLKQVIRIAEERSDFIIFSGGLGPTKDDL
TKETIANTLGRPLVLNDEAFQSIEDYFKRTKRTMSPNNRKQALVIEGSDVLANHFGMAPGMLTEHESRYYMLLPGPPSEL
RPMFENEAKPLLLKKMGSNEKIVSTVLRFFGIGESQLEADLEDIIDAQTNPTIAPLAADGEVTLRLTAKHADEKETERLL
KETEAVILERVGEFFYGYDDTSLVKELSIACKEKGITISAAESFTGGLFSEWLTDHSGASKLFAGGVVCYTNDVKQNVLG
VKKETLDRFGAVSKECASELAKGVQKLTGSDIGISFTGVAGPDAQEGHEPGHVFIGISANGKEEVHEFHFAGSRTGIRKR
GAKYGCHLILKLLEQK

Nucleotide


Download         Length: 1251 bp        

>NTDB_id=722888 NX050_RS12715 WP_003231847.1 2347424..2348674(-) (cinA) [Bacillus subtilis strain PN176 (HK176)]
ATGGAATTTCCAAAAAAAGCAGAAATAATTGCAGTCGGTTCAGAGCTGCTGCTTGGCCAAATCGCCAATACAAATGCTCA
ATTTATCAGCAAACAGCTCGCTGAAATCGGGGTCAACGTATTTTATCATACAGCGGTCGGAGATAACCCGGAGCGGCTGA
AGCAGGTCATCCGCATTGCTGAAGAACGCTCTGACTTCATTATTTTTTCAGGAGGGCTTGGACCCACAAAAGATGATCTG
ACGAAAGAAACGATTGCAAATACGCTGGGACGTCCGCTTGTGTTAAATGATGAGGCATTCCAATCCATTGAGGACTATTT
CAAACGAACAAAACGCACGATGTCACCTAATAACCGAAAACAGGCGCTTGTGATCGAAGGCTCTGACGTGCTGGCGAATC
ACTTTGGAATGGCCCCGGGAATGCTCACAGAGCATGAATCGCGCTATTATATGCTTCTTCCTGGACCGCCGAGCGAATTG
CGTCCAATGTTTGAAAACGAGGCAAAGCCTCTTCTGCTGAAAAAGATGGGTTCAAATGAAAAAATTGTGTCAACCGTTCT
TCGCTTTTTCGGTATCGGTGAATCTCAGCTTGAAGCCGATTTGGAAGATATTATTGATGCGCAAACCAATCCGACAATTG
CGCCTTTGGCGGCTGATGGAGAGGTGACGCTGCGTCTGACAGCCAAACACGCCGATGAAAAGGAAACAGAGCGTCTGTTA
AAAGAAACAGAGGCCGTTATCTTAGAGCGTGTCGGTGAATTTTTCTATGGTTACGATGATACTTCTCTTGTAAAAGAGCT
ATCTATAGCGTGCAAGGAAAAAGGCATTACAATTTCTGCGGCAGAAAGCTTTACCGGAGGGCTGTTTTCTGAATGGCTGA
CGGATCATAGCGGTGCCTCAAAATTATTTGCCGGGGGCGTTGTTTGCTATACAAACGACGTGAAGCAGAATGTGCTTGGT
GTCAAGAAGGAAACATTAGATCGTTTTGGGGCGGTCAGCAAGGAGTGCGCATCCGAACTGGCTAAGGGTGTTCAAAAACT
CACTGGCAGCGATATCGGCATCAGCTTTACTGGTGTAGCAGGACCTGATGCTCAAGAAGGGCATGAGCCTGGGCATGTGT
TTATCGGCATTTCCGCAAATGGTAAAGAAGAGGTTCACGAGTTTCACTTTGCGGGCTCCAGAACGGGGATCAGAAAACGC
GGCGCTAAATACGGCTGCCATTTAATCTTAAAGCTTTTAGAGCAAAAATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(262-412)

Probable molybdopterin binding domain (MoCF_biosynth)

(9-172)

Damage-inducible protein CinA KH domain (CinA_KH)

(184-257)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A199WIX6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Bacillus subtilis subsp. subtilis str. 168

100

100

1
  cinA Streptococcus mitis NCTC 12261

45.694

100

0.459
  cinA Streptococcus mitis SK321

45.694

100

0.459
  cinA Streptococcus pneumoniae TIGR4

45.455

100

0.457
  cinA Streptococcus mutans UA159

46.005

99.279

0.457
  cinA Streptococcus pneumoniae Rx1

45.215

100

0.454
  cinA Streptococcus pneumoniae R6

45.215

100

0.454
  cinA Streptococcus pneumoniae D39

44.976

100

0.452
  cinA Streptococcus suis isolate S10

41.379

90.625

0.375