Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PT288_RS22040 Genome accession   NZ_CP117960
Coordinates   4585608..4586264 (+) Length   218 a.a.
NCBI ID   WP_000611329.1    Uniprot ID   -
Organism   Escherichia coli strain B-3008     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4580608..4591264
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PT288_RS22010 dcyD 4581487..4582473 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  PT288_RS22015 tcyL 4582488..4583156 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  PT288_RS22020 tcyN 4583153..4583905 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  PT288_RS22025 sdiA 4584135..4584857 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  PT288_RS22030 yecF 4584925..4585149 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  PT288_RS22035 yecU 4585136..4585312 (-) 177 WP_000590344.1 protein YecU -
  PT288_RS22880 - 4585350..4585466 (-) 117 WP_001302039.1 hypothetical protein -
  PT288_RS22040 letA 4585608..4586264 (+) 657 WP_000611329.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  PT288_RS22045 uvrC 4586261..4588093 (+) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  PT288_RS22050 pgsA 4588150..4588698 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PT288_RS22070 yecA 4589347..4590012 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=719797 PT288_RS22040 WP_000611329.1 4585608..4586264(+) (letA) [Escherichia coli strain B-3008]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKSAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=719797 PT288_RS22040 WP_000611329.1 4585608..4586264(+) (letA) [Escherichia coli strain B-3008]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAAGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-116)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482