Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   EL277_RS10565 Genome accession   NZ_AP018936
Coordinates   1972993..1973319 (-) Length   108 a.a.
NCBI ID   WP_000738627.1    Uniprot ID   A0A0H2URU9
Organism   Streptococcus pneumoniae strain NU83127     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1967993..1978319
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL277_RS10525 (SPNU_1988) rnpA 1968010..1968381 (-) 372 WP_000739253.1 ribonuclease P protein component -
  EL277_RS12635 - 1968398..1968529 (-) 132 WP_000768904.1 hypothetical protein -
  EL277_RS10530 (SPNU_1989) - 1968530..1969720 (-) 1191 WP_000167757.1 acetate kinase -
  EL277_RS10535 (SPNU_1990) comYH 1969771..1970724 (-) 954 WP_000345135.1 class I SAM-dependent methyltransferase Machinery gene
  EL277_RS10540 - 1970785..1971379 (-) 595 Protein_1954 class I SAM-dependent methyltransferase -
  EL277_RS10545 (SPNU_1993) comGG/cglG 1971516..1971929 (-) 414 WP_000265622.1 competence type IV pilus minor pilin ComGG Machinery gene
  EL277_RS10550 (SPNU_1994) comGF/cglF 1971907..1972368 (-) 462 WP_000250534.1 competence type IV pilus minor pilin ComGF Machinery gene
  EL277_RS10555 (SPNU_1995) comGE/cglE 1972331..1972633 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  EL277_RS10560 (SPNU_1996) comGD/cglD 1972596..1973000 (-) 405 WP_000588028.1 competence type IV pilus minor pilin ComGD Machinery gene
  EL277_RS10565 (SPNU_1997) comGC/cglC 1972993..1973319 (-) 327 WP_000738627.1 comG operon protein ComGC Machinery gene
  EL277_RS10570 (SPNU_1998) comGB/cglB 1973321..1974337 (-) 1017 WP_074196785.1 competence type IV pilus assembly protein ComGB Machinery gene
  EL277_RS10575 (SPNU_1999) comGA/cglA/cilD 1974285..1975226 (-) 942 WP_000249564.1 competence type IV pilus ATPase ComGA Machinery gene
  EL277_RS10580 (SPNU_2000) - 1975302..1975667 (-) 366 WP_000286415.1 DUF1033 family protein -
  EL277_RS10585 (SPNU_2001) - 1975818..1976876 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  EL277_RS10590 (SPNU_2002) nagA 1977039..1978190 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12177.34 Da        Isoelectric Point: 10.1876

>NTDB_id=71825 EL277_RS10565 WP_000738627.1 1972993..1973319(-) (comGC/cglC) [Streptococcus pneumoniae strain NU83127]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQA
DGRITEEQAKAYKEYNDKNGGANRKVND

Nucleotide


Download         Length: 327 bp        

>NTDB_id=71825 EL277_RS10565 WP_000738627.1 1972993..1973319(-) (comGC/cglC) [Streptococcus pneumoniae strain NU83127]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAGATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTAGAAAAGAATGAAGATGCTAGCCTAAGAAAGTTACAAGCA
GATGGACGCATCACGGAAGAACAGGCTAAAGCTTATAAAGAATACAATGATAAAAATGGAGGAGCAAATCGTAAAGTCAA
TGATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 5NCA

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae TIGR4

100

100

1
  comGC/cglC Streptococcus pneumoniae Rx1

99.074

100

0.991
  comGC/cglC Streptococcus pneumoniae D39

99.074

100

0.991
  comGC/cglC Streptococcus pneumoniae R6

99.074

100

0.991
  comGC/cglC Streptococcus mitis SK321

94.444

100

0.944
  comGC/cglC Streptococcus mitis NCTC 12261

94.898

90.741

0.861
  comYC Streptococcus gordonii str. Challis substr. CH1

67.961

95.37

0.648
  comYC Streptococcus mutans UA140

62.745

94.444

0.593
  comYC Streptococcus mutans UA159

62.745

94.444

0.593
  comYC Streptococcus suis isolate S10

70.37

75

0.528
  comGC Lactococcus lactis subsp. cremoris KW2

53.922

94.444

0.509
  comGC Staphylococcus aureus MW2

50

79.63

0.398
  comGC Staphylococcus aureus N315

50

79.63

0.398
  comGC Latilactobacillus sakei subsp. sakei 23K

45.349

79.63

0.361

Multiple sequence alignment