Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilT   Type   Machinery gene
Locus tag   MZN68_RS09765 Genome accession   NZ_CP096117
Coordinates   1938046..1939089 (-) Length   347 a.a.
NCBI ID   WP_002226887.1    Uniprot ID   -
Organism   Neisseria meningitidis strain DFS-1910310016     
Function   power the assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1933046..1944089
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MZN68_RS09755 (MZN68_09585) yccS 1934221..1936371 (-) 2151 WP_002220096.1 YccS family putative transporter -
  MZN68_RS09760 (MZN68_09590) - 1936657..1937883 (-) 1227 WP_002218483.1 PilT/PilU family type 4a pilus ATPase -
  MZN68_RS09765 (MZN68_09595) pilT 1938046..1939089 (-) 1044 WP_002226887.1 type IV pilus twitching motility protein PilT Machinery gene
  MZN68_RS09770 (MZN68_09600) - 1939209..1939895 (+) 687 WP_002242149.1 YggS family pyridoxal phosphate-dependent enzyme -
  MZN68_RS09775 (MZN68_09605) - 1939895..1940302 (+) 408 WP_002242150.1 hypothetical protein -
  MZN68_RS09780 (MZN68_09610) proC 1940351..1941142 (+) 792 WP_002215263.1 pyrroline-5-carboxylate reductase -
  MZN68_RS09785 (MZN68_09615) dksA 1941289..1941705 (+) 417 WP_002215267.1 RNA polymerase-binding protein DksA -

Sequence

Protein


Download         Length: 347 a.a.        Molecular weight: 38037.48 Da        Isoelectric Point: 7.0893

>NTDB_id=679526 MZN68_RS09765 WP_002226887.1 1938046..1939089(-) (pilT) [Neisseria meningitidis strain DFS-1910310016]
MQITDLLAFGAKNKASDLHLSSGISPMIRVHGDMRRINLPEMSAEEVGNMVTSVMNDHQRKIYQQNLEVDFSFELPNVAR
FRVNAFNTGRGPAAVFRTIPSTVLSLEELKAPSIFQKIAESPRGMVLVTGPTGSGKSTTLAAMINYINETQPAHILTIED
PIEFVHQSKKSLINQRELHQHTLSFANALRSALREDPDVILVGEMRDPETIGLALTAAETGHLVFGTLHTTGAAKTVDRI
VDVFPAGEKEMVRSMLSESLTAVISQNLLKTHDGNGRVASHEILIANPAVRNLIRENKITQINSVLQTGQASGMQTMDQS
LQSLVRQGLIAPEVARRRAQNSESMSF

Nucleotide


Download         Length: 1044 bp        

>NTDB_id=679526 MZN68_RS09765 WP_002226887.1 1938046..1939089(-) (pilT) [Neisseria meningitidis strain DFS-1910310016]
ATGCAGATTACCGACTTACTCGCCTTCGGCGCTAAAAACAAAGCATCCGACCTTCACCTGAGTTCGGGCATATCCCCTAT
GATTCGGGTTCACGGCGATATGCGGCGCATCAACCTTCCCGAAATGAGCGCGGAAGAGGTCGGTAATATGGTAACTTCGG
TGATGAACGACCACCAGCGGAAAATCTACCAGCAAAACTTGGAAGTCGACTTCTCGTTCGAACTGCCCAACGTCGCCCGA
TTCCGCGTCAACGCCTTCAACACCGGCCGCGGTCCCGCCGCCGTATTCCGCACCATTCCCAGCACCGTCTTATCGCTGGA
AGAATTGAAAGCCCCGAGCATTTTCCAAAAAATCGCAGAATCGCCGCGCGGCATGGTATTGGTTACCGGCCCTACCGGTT
CGGGCAAATCGACCACGCTTGCCGCGATGATCAACTACATCAACGAAACCCAGCCGGCACACATCCTGACCATCGAAGAC
CCGATCGAATTCGTCCACCAAAGCAAAAAATCCCTGATTAACCAGCGCGAGCTGCACCAGCACACCCTCAGCTTCGCCAA
CGCGCTGCGTTCCGCATTGCGCGAAGACCCCGACGTTATCCTTGTCGGCGAGATGCGCGACCCCGAAACCATCGGCTTGG
CACTGACCGCCGCCGAAACCGGACACTTGGTTTTCGGCACGCTGCACACGACCGGCGCAGCAAAAACCGTCGACCGTATC
GTGGACGTATTCCCGGCGGGAGAAAAAGAAATGGTGCGCTCTATGCTGTCCGAATCGCTGACCGCCGTCATCTCCCAAAA
CCTGCTGAAAACGCACGACGGCAACGGCCGTGTCGCCTCGCACGAAATCCTGATTGCCAACCCCGCCGTCCGCAACCTCA
TCCGCGAAAACAAAATCACGCAGATTAACTCCGTCCTGCAAACCGGGCAGGCGAGCGGTATGCAGACAATGGACCAATCG
CTGCAATCGCTGGTGCGCCAAGGGCTGATCGCACCGGAAGTCGCACGCAGACGCGCGCAAAACAGCGAAAGTATGAGTTT
CTGA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(12-270)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilT Neisseria meningitidis 8013

99.712

100

0.997
  pilT Neisseria gonorrhoeae MS11

99.424

100

0.994
  pilT Acinetobacter baumannii D1279779

68.116

99.424

0.677
  pilT Acinetobacter baumannii strain A118

68.116

99.424

0.677
  pilT Acinetobacter nosocomialis M2

68.116

99.424

0.677
  pilT Acinetobacter baylyi ADP1

67.536

99.424

0.671
  pilT Pseudomonas stutzeri DSM 10701

67.246

99.424

0.669
  pilT Pseudomonas aeruginosa PAK

66.667

99.424

0.663
  pilT Legionella pneumophila strain Lp02

64.809

98.271

0.637
  pilT Legionella pneumophila strain ERS1305867

64.809

98.271

0.637
  pilT Vibrio cholerae O1 biovar El Tor strain E7946

64.545

95.101

0.614
  pilT Vibrio cholerae strain A1552

64.545

95.101

0.614
  pilT Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539

53.687

97.695

0.524
  pilU Pseudomonas stutzeri DSM 10701

40.29

99.424

0.401
  pilU Vibrio cholerae strain A1552

38.329

100

0.383
  pilU Acinetobacter baylyi ADP1

38.439

99.712

0.383