Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   LXA49_RS10055 Genome accession   NZ_CP089949
Coordinates   1942930..1943253 (-) Length   107 a.a.
NCBI ID   WP_000738628.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain SN75752     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1937930..1948253
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LXA49_RS10015 (LXA49_10000) rnpA 1937950..1938321 (-) 372 WP_000739246.1 ribonuclease P protein component -
  LXA49_RS11180 - 1938338..1938469 (-) 132 WP_000768904.1 hypothetical protein -
  LXA49_RS10020 (LXA49_10005) - 1938470..1939660 (-) 1191 WP_000167765.1 acetate kinase -
  LXA49_RS10025 (LXA49_10010) comYH 1939711..1940664 (-) 954 WP_000345126.1 class I SAM-dependent methyltransferase Machinery gene
  LXA49_RS10030 (LXA49_10015) - 1940725..1941317 (-) 593 Protein_1976 methyltransferase domain-containing protein -
  LXA49_RS10035 (LXA49_10020) comGG/cglG 1941420..1941866 (-) 447 WP_001809944.1 competence type IV pilus minor pilin ComGG Machinery gene
  LXA49_RS10040 (LXA49_10025) comGF/cglF 1941844..1942305 (-) 462 WP_000250531.1 competence type IV pilus minor pilin ComGF Machinery gene
  LXA49_RS10045 (LXA49_10030) comGE/cglE 1942268..1942570 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  LXA49_RS10050 (LXA49_10035) comGD/cglD 1942533..1942967 (-) 435 WP_033606693.1 competence type IV pilus minor pilin ComGD Machinery gene
  LXA49_RS10055 (LXA49_10040) comGC/cglC 1942930..1943253 (-) 324 WP_000738628.1 comG operon protein ComGC Machinery gene
  LXA49_RS10060 (LXA49_10045) comGB/cglB 1943255..1944271 (-) 1017 WP_078130737.1 competence type IV pilus assembly protein ComGB Machinery gene
  LXA49_RS10065 (LXA49_10050) comGA/cglA/cilD 1944219..1945160 (-) 942 WP_000249536.1 competence type IV pilus ATPase ComGA Machinery gene
  LXA49_RS10070 (LXA49_10055) - 1945236..1945601 (-) 366 WP_000286415.1 DUF1033 family protein -
  LXA49_RS10075 (LXA49_10060) - 1945752..1946810 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  LXA49_RS10080 (LXA49_10065) nagA 1946973..1948124 (-) 1152 WP_252948148.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 107 a.a.        Molecular weight: 12232.41 Da        Isoelectric Point: 9.8887

>NTDB_id=639449 LXA49_RS10055 WP_000738628.1 1942930..1943253(-) (comGC/cglC) [Streptococcus pneumoniae strain SN75752]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQD
DGRITEEQAKAYKEYHDKQNTSQIVKD

Nucleotide


Download         Length: 324 bp        

>NTDB_id=639449 LXA49_RS10055 WP_000738628.1 1942930..1943253(-) (comGC/cglC) [Streptococcus pneumoniae strain SN75752]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAAATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGAAAAGAATGAAGATGCTAGCCTAAGAAAGTTACAAGAC
GATGGACGCATCACGGAAGAACAGGCTAAAGCCTATAAAGAATACCATGATAAACAAAATACTAGTCAAATCGTTAAAGA
TTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis NCTC 12261

93.458

100

0.935
  comGC/cglC Streptococcus pneumoniae D39

94.175

96.262

0.907
  comGC/cglC Streptococcus pneumoniae R6

94.175

96.262

0.907
  comGC/cglC Streptococcus pneumoniae Rx1

94.175

96.262

0.907
  comGC/cglC Streptococcus pneumoniae TIGR4

93.204

96.262

0.897
  comGC/cglC Streptococcus mitis SK321

88.35

96.262

0.85
  comYC Streptococcus gordonii str. Challis substr. CH1

69.388

91.589

0.636
  comYC Streptococcus mutans UA140

64.211

88.785

0.57
  comYC Streptococcus mutans UA159

64.211

88.785

0.57
  comYC Streptococcus suis isolate S10

69.136

75.701

0.523
  comGC Lactococcus lactis subsp. cremoris KW2

54.639

90.654

0.495
  comGC Staphylococcus aureus MW2

48.837

80.374

0.393
  comGC Staphylococcus aureus N315

48.837

80.374

0.393
  comGC Latilactobacillus sakei subsp. sakei 23K

45.349

80.374

0.364