Detailed information NTG0639446

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: LXA49_RS10040
• Genome accession: NZ_CP089949
• Coordinates: 1941844..1942305 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250531.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain SN75752
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1936844..1947305

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LXA49_RS10010 (LXA49_09995)	-	1937151..1937975 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
LXA49_RS10015 (LXA49_10000)	rnpA	1937950..1938321 (-)	372	WP_000739246.1	ribonuclease P protein component	-
LXA49_RS11180	-	1938338..1938469 (-)	132	WP_000768904.1	hypothetical protein	-
LXA49_RS10020 (LXA49_10005)	-	1938470..1939660 (-)	1191	WP_000167765.1	acetate kinase	-
LXA49_RS10025 (LXA49_10010)	comYH	1939711..1940664 (-)	954	WP_000345126.1	class I SAM-dependent methyltransferase	Machinery gene
LXA49_RS10030 (LXA49_10015)	-	1940725..1941317 (-)	593	Protein_1976	methyltransferase domain-containing protein	-
LXA49_RS10035 (LXA49_10020)	comGG/cglG	1941420..1941866 (-)	447	WP_001809944.1	competence type IV pilus minor pilin ComGG	Machinery gene
LXA49_RS10040 (LXA49_10025)	comGF/cglF	1941844..1942305 (-)	462	WP_000250531.1	competence type IV pilus minor pilin ComGF	Machinery gene
LXA49_RS10045 (LXA49_10030)	comGE/cglE	1942268..1942570 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
LXA49_RS10050 (LXA49_10035)	comGD/cglD	1942533..1942967 (-)	435	WP_033606693.1	competence type IV pilus minor pilin ComGD	Machinery gene
LXA49_RS10055 (LXA49_10040)	comGC/cglC	1942930..1943253 (-)	324	WP_000738628.1	comG operon protein ComGC	Machinery gene
LXA49_RS10060 (LXA49_10045)	comGB/cglB	1943255..1944271 (-)	1017	WP_078130737.1	competence type IV pilus assembly protein ComGB	Machinery gene
LXA49_RS10065 (LXA49_10050)	comGA/cglA/cilD	1944219..1945160 (-)	942	WP_000249536.1	competence type IV pilus ATPase ComGA	Machinery gene
LXA49_RS10070 (LXA49_10055)	-	1945236..1945601 (-)	366	WP_000286415.1	DUF1033 family protein	-
LXA49_RS10075 (LXA49_10060)	-	1945752..1946810 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17849.37 Da
• Isoelectric Point: 6.4832

>NTDB_id=639446 LXA49_RS10040 WP_000250531.1 1941844..1942305(-) (comGF/cglF) [Streptococcus pneumoniae strain SN75752]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLISEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES

Nucleotide

• Length: 462 bp

>NTDB_id=639446 LXA49_RS10040 WP_000250531.1 1941844..1942305(-) (comGF/cglF) [Streptococcus pneumoniae strain SN75752]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAGCTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGTAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAGAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	95.425	100	0.954
comGF/cglF	Streptococcus pneumoniae D39	95.425	100	0.954
comGF/cglF	Streptococcus pneumoniae R6	95.425	100	0.954
comGF/cglF	Streptococcus pneumoniae TIGR4	95.425	100	0.954
comGF/cglF	Streptococcus mitis SK321	92.81	100	0.928
comGF/cglF	Streptococcus mitis NCTC 12261	91.503	100	0.915