Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   LXA49_RS10025 Genome accession   NZ_CP089949
Coordinates   1939711..1940664 (-) Length   317 a.a.
NCBI ID   WP_000345126.1    Uniprot ID   A0A0F7YBB9
Organism   Streptococcus pneumoniae strain SN75752     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1934711..1945664
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LXA49_RS10000 (LXA49_09985) - 1935472..1936095 (-) 624 WP_000932658.1 hypothetical protein -
  LXA49_RS10005 (LXA49_09990) jag 1936146..1937132 (-) 987 WP_000260018.1 RNA-binding cell elongation regulator Jag/EloR -
  LXA49_RS10010 (LXA49_09995) - 1937151..1937975 (-) 825 WP_000727904.1 membrane protein insertase YidC -
  LXA49_RS10015 (LXA49_10000) rnpA 1937950..1938321 (-) 372 WP_000739246.1 ribonuclease P protein component -
  LXA49_RS11180 - 1938338..1938469 (-) 132 WP_000768904.1 hypothetical protein -
  LXA49_RS10020 (LXA49_10005) - 1938470..1939660 (-) 1191 WP_000167765.1 acetate kinase -
  LXA49_RS10025 (LXA49_10010) comYH 1939711..1940664 (-) 954 WP_000345126.1 class I SAM-dependent methyltransferase Machinery gene
  LXA49_RS10030 (LXA49_10015) - 1940725..1941317 (-) 593 Protein_1976 methyltransferase domain-containing protein -
  LXA49_RS10035 (LXA49_10020) comGG/cglG 1941420..1941866 (-) 447 WP_001809944.1 competence type IV pilus minor pilin ComGG Machinery gene
  LXA49_RS10040 (LXA49_10025) comGF/cglF 1941844..1942305 (-) 462 WP_000250531.1 competence type IV pilus minor pilin ComGF Machinery gene
  LXA49_RS10045 (LXA49_10030) comGE/cglE 1942268..1942570 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  LXA49_RS10050 (LXA49_10035) comGD/cglD 1942533..1942967 (-) 435 WP_033606693.1 competence type IV pilus minor pilin ComGD Machinery gene
  LXA49_RS10055 (LXA49_10040) comGC/cglC 1942930..1943253 (-) 324 WP_000738628.1 comG operon protein ComGC Machinery gene
  LXA49_RS10060 (LXA49_10045) comGB/cglB 1943255..1944271 (-) 1017 WP_078130737.1 competence type IV pilus assembly protein ComGB Machinery gene
  LXA49_RS10065 (LXA49_10050) comGA/cglA/cilD 1944219..1945160 (-) 942 WP_000249536.1 competence type IV pilus ATPase ComGA Machinery gene
  LXA49_RS10070 (LXA49_10055) - 1945236..1945601 (-) 366 WP_000286415.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35714.87 Da        Isoelectric Point: 4.2434

>NTDB_id=639444 LXA49_RS10025 WP_000345126.1 1939711..1940664(-) (comYH) [Streptococcus pneumoniae strain SN75752]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFILQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=639444 LXA49_RS10025 WP_000345126.1 1939711..1940664(-) (comYH) [Streptococcus pneumoniae strain SN75752]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAACAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC
AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCGGATGCTATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAGTGGATGATTTACTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTTGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGCTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGAATGGCTGAAAGAAGAGGCGAGTCTGGTTGCTATGATTAGTCTGCCTGAAAATCTCTTTGCTAA
TGCTAAACAATCTAAGACTATTTTTATCCTACAGAAGAAAAATGAAATAGCAGTAGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F7YBB9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.633

98.738

0.539
  comYH Streptococcus mutans UA159

54.313

98.738

0.536