Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGD/cglD   Type   Machinery gene
Locus tag   LXA49_RS10050 Genome accession   NZ_CP089949
Coordinates   1942533..1942967 (-) Length   144 a.a.
NCBI ID   WP_033606693.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain SN75752     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 1937533..1947967
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LXA49_RS10015 (LXA49_10000) rnpA 1937950..1938321 (-) 372 WP_000739246.1 ribonuclease P protein component -
  LXA49_RS11180 - 1938338..1938469 (-) 132 WP_000768904.1 hypothetical protein -
  LXA49_RS10020 (LXA49_10005) - 1938470..1939660 (-) 1191 WP_000167765.1 acetate kinase -
  LXA49_RS10025 (LXA49_10010) comYH 1939711..1940664 (-) 954 WP_000345126.1 class I SAM-dependent methyltransferase Machinery gene
  LXA49_RS10030 (LXA49_10015) - 1940725..1941317 (-) 593 Protein_1976 methyltransferase domain-containing protein -
  LXA49_RS10035 (LXA49_10020) comGG/cglG 1941420..1941866 (-) 447 WP_001809944.1 competence type IV pilus minor pilin ComGG Machinery gene
  LXA49_RS10040 (LXA49_10025) comGF/cglF 1941844..1942305 (-) 462 WP_000250531.1 competence type IV pilus minor pilin ComGF Machinery gene
  LXA49_RS10045 (LXA49_10030) comGE/cglE 1942268..1942570 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  LXA49_RS10050 (LXA49_10035) comGD/cglD 1942533..1942967 (-) 435 WP_033606693.1 competence type IV pilus minor pilin ComGD Machinery gene
  LXA49_RS10055 (LXA49_10040) comGC/cglC 1942930..1943253 (-) 324 WP_000738628.1 comG operon protein ComGC Machinery gene
  LXA49_RS10060 (LXA49_10045) comGB/cglB 1943255..1944271 (-) 1017 WP_078130737.1 competence type IV pilus assembly protein ComGB Machinery gene
  LXA49_RS10065 (LXA49_10050) comGA/cglA/cilD 1944219..1945160 (-) 942 WP_000249536.1 competence type IV pilus ATPase ComGA Machinery gene
  LXA49_RS10070 (LXA49_10055) - 1945236..1945601 (-) 366 WP_000286415.1 DUF1033 family protein -
  LXA49_RS10075 (LXA49_10060) - 1945752..1946810 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence


Protein


Download         Length: 144 a.a.        Molecular weight: 15802.39 Da        Isoelectric Point: 10.5150

>NTDB_id=639448 LXA49_RS10050 WP_033606693.1 1942533..1942967(-) (comGD/cglD) [Streptococcus pneumoniae strain SN75752]
MINKILVKSLKIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVEEQIFFMEFEELYRETQKRSVASQQKTSLNLDGQM
ISNGSQKLPVPKGIQAPSGQSITFDRAGGNSSLAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN

Nucleotide


Download         Length: 435 bp        

>NTDB_id=639448 LXA49_RS10050 WP_033606693.1 1942533..1942967(-) (comGD/cglD) [Streptococcus pneumoniae strain SN75752]
ATGATAAACAAAATACTAGTCAAATCGTTAAAGATTAAGGCCTTTACCATGCTGGAAAGTCTCTTGGTTTTGGGACTTGT
GAGTATCCTTGCCTTGGGCTTGTCCGGCTCTGTCCAGTCCACTTTTGCAGCGGTAGAGGAACAGATTTTCTTTATGGAGT
TTGAAGAACTCTATCGGGAAACCCAAAAACGCAGTGTAGCTAGTCAACAAAAGACTAGTCTGAACTTGGATGGGCAGATG
ATTAGCAATGGCAGTCAAAAGTTGCCAGTCCCTAAAGGAATTCAGGCCCCATCAGGCCAAAGTATTACATTTGACCGTGC
TGGGGGCAATTCGTCCCTGGCTAAGGTTGAATTTCAGACCAGTAAAGGAGCGATTCGCTATCAATTATATCTAGGAAATG
GAAAAATTAAACGCATTAAGGAAACAAAAAATTAG

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGD/cglD Streptococcus mitis NCTC 12261

94.444

100

0.944

  comGD/cglD Streptococcus pneumoniae Rx1

98.496

92.361

0.91

  comGD/cglD Streptococcus pneumoniae D39

98.496

92.361

0.91

  comGD/cglD Streptococcus pneumoniae R6

98.496

92.361

0.91

  comGD/cglD Streptococcus pneumoniae TIGR4

97.744

92.361

0.903

  comGD/cglD Streptococcus mitis SK321

96.241

92.361

0.889

  comYD Streptococcus gordonii str. Challis substr. CH1

56.835

96.528

0.549

  comYD Streptococcus mutans UA140

49.612

89.583

0.444

  comYD Streptococcus mutans UA159

49.612

89.583

0.444