Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   LXA49_RS10060 Genome accession   NZ_CP089949
Coordinates   1943255..1944271 (-) Length   338 a.a.
NCBI ID   WP_078130737.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain SN75752     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1938255..1949271
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LXA49_RS11180 - 1938338..1938469 (-) 132 WP_000768904.1 hypothetical protein -
  LXA49_RS10020 (LXA49_10005) - 1938470..1939660 (-) 1191 WP_000167765.1 acetate kinase -
  LXA49_RS10025 (LXA49_10010) comYH 1939711..1940664 (-) 954 WP_000345126.1 class I SAM-dependent methyltransferase Machinery gene
  LXA49_RS10030 (LXA49_10015) - 1940725..1941317 (-) 593 Protein_1976 methyltransferase domain-containing protein -
  LXA49_RS10035 (LXA49_10020) comGG/cglG 1941420..1941866 (-) 447 WP_001809944.1 competence type IV pilus minor pilin ComGG Machinery gene
  LXA49_RS10040 (LXA49_10025) comGF/cglF 1941844..1942305 (-) 462 WP_000250531.1 competence type IV pilus minor pilin ComGF Machinery gene
  LXA49_RS10045 (LXA49_10030) comGE/cglE 1942268..1942570 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  LXA49_RS10050 (LXA49_10035) comGD/cglD 1942533..1942967 (-) 435 WP_033606693.1 competence type IV pilus minor pilin ComGD Machinery gene
  LXA49_RS10055 (LXA49_10040) comGC/cglC 1942930..1943253 (-) 324 WP_000738628.1 comG operon protein ComGC Machinery gene
  LXA49_RS10060 (LXA49_10045) comGB/cglB 1943255..1944271 (-) 1017 WP_078130737.1 competence type IV pilus assembly protein ComGB Machinery gene
  LXA49_RS10065 (LXA49_10050) comGA/cglA/cilD 1944219..1945160 (-) 942 WP_000249536.1 competence type IV pilus ATPase ComGA Machinery gene
  LXA49_RS10070 (LXA49_10055) - 1945236..1945601 (-) 366 WP_000286415.1 DUF1033 family protein -
  LXA49_RS10075 (LXA49_10060) - 1945752..1946810 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  LXA49_RS10080 (LXA49_10065) nagA 1946973..1948124 (-) 1152 WP_252948148.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38523.66 Da        Isoelectric Point: 9.8240

>NTDB_id=639450 LXA49_RS10060 WP_078130737.1 1943255..1944271(-) (comGB/cglB) [Streptococcus pneumoniae strain SN75752]
MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLDRSALLDKQCVTQMRVGLSQGKSFSEMMKSLGCSSAI
VTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLFFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQGMELTQIFQMMQEQGSQLFKEI
GQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=639450 LXA49_RS10060 WP_078130737.1 1943255..1944271(-) (comGB/cglB) [Streptococcus pneumoniae strain SN75752]
ATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAAGCAAAAAAATATCATCACCCTATTTAA
CAATCTCTTTTCTAGCGGTTTTCATCTGGTGGAGACTATCTCCTTTTTAGATAGGAGTGCTTTGTTGGACAAGCAGTGTG
TGACCCAGATGCGTGTGGGCTTGTCTCAGGGGAAATCATTCTCAGAAATGATGAAAAGTTTGGGATGTTCAAGTGCTATT
GTCACTCAGTTATCCCTAGCTGAAGTCCATGGTAATCTCCACCTGAGTTTGGGAAAGATAGAAGAGTATCTAGACAATCT
GGCCAAGGTCAAGAAAAAATTAATTGAAGTAGCGACCTATCCTTTGATTTTGCTGTTTTTTCTTCTCTTAATTATGCTGG
GGCTACGGAATTACCTGCTCCCACAACTGGATAGTAGCAATATTGCCACCCGAATTATCGGTAATCTGCCACAAATTTTT
CTAGGCATGGTAGGGCTTGTTTCCGTGCTTGCCCTTTTAGCACTAACTTTTTATAAAAGAAGTTCTAAGATGAGTGTCTT
TTCTATCTTAGCACGCCTTCCCTTTATTGGAATCTTTGTGCAGACCTACTTGACAGCCTATTATGCACGTGAATGGGGGA
ATATGATTTCACAGGGAATGGAGCTGACGCAGATTTTTCAAATGATGCAGGAACAAGGTTCCCAGCTCTTTAAAGAAATC
GGTCAAGATCTGGCTCAAACCCTGAAAAATGGCCGTGAATTTTCTCAGACGATAGGAACCTATCCTTTCTTTAGGAAGGA
ATTGAGTCTCATCATAGAGTATGGGGAAGTTAAGTCCAAGCTGGGTAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGCCTTTTTTACCCGAGTCAACCGCACCATGAATTTGGTGCAGCCACTGGTTTTTATTTTTGTGGCACTGATTATCGTT
TTACTTTATGCGGCAATGCTCATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus pneumoniae Rx1

98.817

100

0.988
  comGB/cglB Streptococcus pneumoniae D39

98.817

100

0.988
  comGB/cglB Streptococcus pneumoniae R6

98.817

100

0.988
  comGB/cglB Streptococcus pneumoniae TIGR4

98.817

100

0.988
  comGB/cglB Streptococcus mitis SK321

94.675

100

0.947
  comGB/cglB Streptococcus mitis NCTC 12261

94.083

100

0.941
  comYB Streptococcus gordonii str. Challis substr. CH1

70.833

99.408

0.704
  comYB Streptococcus mutans UA140

58.176

94.083

0.547
  comYB Streptococcus mutans UA159

58.176

94.083

0.547
  comGB Lactococcus lactis subsp. cremoris KW2

50.599

98.817

0.5