Detailed information NTG0547027

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: J1N58_RS00795
• Genome accession: NZ_CP071697
• Coordinates: 138594..138875 (+)
• Length: 93 a.a.
• NCBI ID: WP_024376296.1
• Uniprot ID: A0A0Z8NQJ2
• Organism: Streptococcus suis strain 1112S
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 133594..143875

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J1N58_RS00775 (J1N58_00775)	-	135261..135638 (+)	378	WP_029175711.1	DUF1033 family protein	-
J1N58_RS00780 (J1N58_00780)	-	135657..136607 (-)	951	WP_029175710.1	S66 peptidase family protein	-
J1N58_RS00785 (J1N58_00785)	comYA	136693..137643 (+)	951	WP_024376298.1	competence type IV pilus ATPase ComGA	Machinery gene
J1N58_RS00790 (J1N58_00790)	comYB	137555..138592 (+)	1038	WP_050571398.1	competence type IV pilus assembly protein ComGB	Machinery gene
J1N58_RS00795 (J1N58_00795)	comYC	138594..138875 (+)	282	WP_024376296.1	competence type IV pilus major pilin ComGC	Machinery gene
J1N58_RS00800 (J1N58_00800)	comGD	138856..139263 (+)	408	WP_024376295.1	competence type IV pilus minor pilin ComGD	-
J1N58_RS00805 (J1N58_00805)	comYE	139235..139528 (+)	294	WP_024376294.1	competence type IV pilus minor pilin ComGE	Machinery gene
J1N58_RS00810 (J1N58_00810)	comGF/cglF	139515..139949 (+)	435	WP_024376293.1	competence type IV pilus minor pilin ComGF	Machinery gene
J1N58_RS00815 (J1N58_00815)	comGG	139927..140442 (+)	516	WP_207560409.1	competence type IV pilus minor pilin ComGG	-
J1N58_RS00820 (J1N58_00820)	comYH	140499..141452 (+)	954	WP_024376291.1	class I SAM-dependent methyltransferase	Machinery gene
J1N58_RS00825 (J1N58_00825)	-	141503..142690 (+)	1188	WP_207560410.1	acetate kinase	-
J1N58_RS00830 (J1N58_00830)	-	143005..143556 (+)	552	WP_207560411.1	folate family ECF transporter S component	-

Sequence

Protein

• Length: 93 a.a.
• Molecular weight: 10402.41 Da
• Isoelectric Point: 9.7128

>NTDB_id=547027 J1N58_RS00795 WP_024376296.1 138594..138875(+) (comYC) [Streptococcus suis strain 1112S]
MKKLLKLKKKAFTLVEMLVVLGIISLLLLIFVPNLSKQKAAVQEKGNAAVVKVVESQMELYELEHDKEATVADLQADGYI
TEKQAEQYAKAKK

Nucleotide

• Length: 282 bp

>NTDB_id=547027 J1N58_RS00795 WP_024376296.1 138594..138875(+) (comYC) [Streptococcus suis strain 1112S]
ATGAAAAAATTGTTGAAATTAAAAAAGAAAGCTTTCACTCTGGTGGAAATGTTAGTTGTTTTGGGTATTATTAGCCTGCT
CTTGCTCATTTTTGTGCCAAATTTGAGCAAGCAAAAAGCAGCTGTTCAAGAGAAAGGAAATGCTGCCGTTGTCAAAGTAG
TAGAGAGCCAGATGGAACTCTATGAATTGGAACATGACAAGGAAGCAACGGTGGCAGACTTGCAAGCGGATGGCTATATT
ACTGAAAAACAAGCGGAGCAGTATGCTAAGGCGAAAAAATAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (8-30)

3D structure

• AlphaFold DB: A0A0Z8NQJ2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus suis isolate S10	83.871	100	0.839
comGC/cglC	Streptococcus pneumoniae TIGR4	66.304	98.925	0.656
comGC/cglC	Streptococcus pneumoniae Rx1	66.304	98.925	0.656
comGC/cglC	Streptococcus pneumoniae D39	66.304	98.925	0.656
comGC/cglC	Streptococcus pneumoniae R6	66.304	98.925	0.656
comGC/cglC	Streptococcus mitis NCTC 12261	66.304	98.925	0.656
comGC/cglC	Streptococcus mitis SK321	66.304	98.925	0.656
comYC	Streptococcus gordonii str. Challis substr. CH1	66.292	95.699	0.634
comYC	Streptococcus mutans UA140	60.227	94.624	0.57
comYC	Streptococcus mutans UA159	60.227	94.624	0.57
comGC	Lactococcus lactis subsp. cremoris KW2	59.091	94.624	0.559
comGC	Staphylococcus aureus MW2	52.941	91.398	0.484
comGC	Staphylococcus aureus N315	52.941	91.398	0.484
comGC	Bacillus subtilis subsp. subtilis str. 168	46.667	80.645	0.376
comGC	Latilactobacillus sakei subsp. sakei 23K	42.5	86.022	0.366