Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   J1N58_RS00785 Genome accession   NZ_CP071697
Coordinates   136693..137643 (+) Length   316 a.a.
NCBI ID   WP_024376298.1    Uniprot ID   -
Organism   Streptococcus suis strain 1112S     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 131693..142643
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J1N58_RS00775 (J1N58_00775) - 135261..135638 (+) 378 WP_029175711.1 DUF1033 family protein -
  J1N58_RS00780 (J1N58_00780) - 135657..136607 (-) 951 WP_029175710.1 S66 peptidase family protein -
  J1N58_RS00785 (J1N58_00785) comYA 136693..137643 (+) 951 WP_024376298.1 competence type IV pilus ATPase ComGA Machinery gene
  J1N58_RS00790 (J1N58_00790) comYB 137555..138592 (+) 1038 WP_050571398.1 competence type IV pilus assembly protein ComGB Machinery gene
  J1N58_RS00795 (J1N58_00795) comYC 138594..138875 (+) 282 WP_024376296.1 competence type IV pilus major pilin ComGC Machinery gene
  J1N58_RS00800 (J1N58_00800) comGD 138856..139263 (+) 408 WP_024376295.1 competence type IV pilus minor pilin ComGD -
  J1N58_RS00805 (J1N58_00805) comYE 139235..139528 (+) 294 WP_024376294.1 competence type IV pilus minor pilin ComGE Machinery gene
  J1N58_RS00810 (J1N58_00810) comGF/cglF 139515..139949 (+) 435 WP_024376293.1 competence type IV pilus minor pilin ComGF Machinery gene
  J1N58_RS00815 (J1N58_00815) comGG 139927..140442 (+) 516 WP_207560409.1 competence type IV pilus minor pilin ComGG -
  J1N58_RS00820 (J1N58_00820) comYH 140499..141452 (+) 954 WP_024376291.1 class I SAM-dependent methyltransferase Machinery gene

Sequence

Protein


Download         Length: 316 a.a.        Molecular weight: 35396.31 Da        Isoelectric Point: 5.6994

>NTDB_id=547025 J1N58_RS00785 WP_024376298.1 136693..137643(+) (comYA) [Streptococcus suis strain 1112S]
MIQEKARKMIEEAVADRVSDIYLVPRGECYQVYHRIMDEREFVQDVAEEEVTAIISHFKFLAGLNVGEKRRSQQGSCDYD
YGSGEISLRLSTVGDYRGKESLVIRLLYDNDKELKFWFEAAERLAEEIKGRGLYLFSGPVGSGKTTLMYHLARLKFPDKQ
ILTIEDPVEIKQEDMLQLQLNEAIGATYDNLIKLSLRHRPDLLIIGEIRDAETARAVIRASLTGATVFSTVHARSISGVY
ARMLELGVSPEELNNALQGIAYQRLIGGGGVVDFAKGNYKNHSADQWNAQIDRLFAAGHISLRQAETEKIALGAPA

Nucleotide


Download         Length: 951 bp        

>NTDB_id=547025 J1N58_RS00785 WP_024376298.1 136693..137643(+) (comYA) [Streptococcus suis strain 1112S]
ATGATTCAAGAAAAAGCAAGAAAGATGATTGAAGAGGCGGTGGCAGATAGGGTCAGTGACATCTATCTAGTTCCTCGAGG
TGAGTGTTACCAAGTCTACCATCGCATCATGGATGAACGGGAGTTTGTGCAAGACGTGGCTGAGGAGGAAGTGACAGCCA
TCATCAGCCATTTCAAGTTTTTAGCAGGTTTAAATGTTGGTGAAAAACGCCGTAGTCAGCAGGGTTCCTGTGACTATGAT
TATGGTAGCGGAGAGATTTCACTTCGCTTATCAACTGTCGGTGATTATCGTGGCAAGGAAAGTCTGGTTATCCGCCTGCT
CTATGACAATGACAAGGAACTTAAGTTCTGGTTTGAGGCGGCCGAGCGGCTTGCAGAAGAAATCAAGGGACGAGGGCTCT
ACCTTTTTTCGGGTCCAGTCGGCTCTGGTAAGACCACACTTATGTACCATCTTGCCAGGCTGAAATTCCCAGACAAGCAG
ATTTTGACCATCGAGGATCCTGTCGAAATCAAGCAGGAGGACATGCTGCAACTCCAGCTCAATGAAGCCATCGGAGCCAC
CTACGATAATTTGATAAAATTATCCCTGCGTCATCGACCGGACCTGCTCATCATCGGTGAAATTCGGGATGCGGAAACAG
CTCGAGCAGTCATTCGAGCCAGCCTGACGGGAGCTACCGTTTTCTCAACGGTTCACGCAAGGTCTATTTCGGGTGTCTAT
GCTCGTATGTTGGAATTGGGGGTCAGTCCTGAAGAGTTAAATAATGCCCTTCAAGGCATTGCCTATCAACGCTTGATCGG
GGGAGGAGGTGTAGTGGATTTTGCAAAGGGAAATTACAAAAACCATTCCGCAGACCAGTGGAATGCGCAAATTGATCGCC
TTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTGCCCTTGGCGCGCCAGCGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

68.71

98.101

0.674
  comYA Streptococcus mutans UA159

67.524

98.418

0.665
  comYA Streptococcus mutans UA140

67.524

98.418

0.665
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

64.952

98.418

0.639
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

64.952

98.418

0.639
  comGA/cglA/cilD Streptococcus pneumoniae R6

64.952

98.418

0.639
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

64.952

98.418

0.639
  comGA/cglA/cilD Streptococcus pneumoniae D39

64.952

98.418

0.639
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

64.516

98.101

0.633
  comGA Lactococcus lactis subsp. cremoris KW2

53.628

100

0.538