Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   HMPREF1038_RS10050 Genome accession   NC_018630
Coordinates   1862276..1862602 (-) Length   108 a.a.
NCBI ID   WP_000738633.1    Uniprot ID   -
Organism   Streptococcus pneumoniae gamPNI0373     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1857276..1867602
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF1038_RS10005 (HMPREF1038_02037) rnpA 1857293..1857664 (-) 372 WP_000739246.1 ribonuclease P protein component -
  HMPREF1038_RS13455 (HMPREF1038_02038) - 1857681..1857812 (-) 132 WP_000768904.1 hypothetical protein -
  HMPREF1038_RS10010 (HMPREF1038_02039) - 1857813..1859003 (-) 1191 WP_000167766.1 acetate kinase -
  HMPREF1038_RS10015 (HMPREF1038_02040) comYH 1859054..1860007 (-) 954 WP_000345116.1 class I SAM-dependent methyltransferase Machinery gene
  HMPREF1038_RS12125 - 1860068..1860662 (-) 595 Protein_1886 class I SAM-dependent methyltransferase -
  HMPREF1038_RS10030 (HMPREF1038_02044) comGG/cglG 1860799..1861212 (-) 414 WP_000265631.1 competence type IV pilus minor pilin ComGG Machinery gene
  HMPREF1038_RS10035 (HMPREF1038_02045) comGF/cglF 1861190..1861651 (-) 462 WP_000250531.1 competence type IV pilus minor pilin ComGF Machinery gene
  HMPREF1038_RS10040 (HMPREF1038_02046) comGE/cglE 1861614..1861916 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  HMPREF1038_RS10045 (HMPREF1038_02047) comGD/cglD 1861879..1862283 (-) 405 WP_000588020.1 competence type IV pilus minor pilin ComGD Machinery gene
  HMPREF1038_RS10050 (HMPREF1038_02048) comGC/cglC 1862276..1862602 (-) 327 WP_000738633.1 comG operon protein ComGC Machinery gene
  HMPREF1038_RS10055 (HMPREF1038_02049) comGB/cglB 1862604..1863620 (-) 1017 WP_001844679.1 competence type IV pilus assembly protein ComGB Machinery gene
  HMPREF1038_RS10060 (HMPREF1038_02050) comGA/cglA/cilD 1863568..1864509 (-) 942 WP_001844680.1 competence type IV pilus ATPase ComGA Machinery gene
  HMPREF1038_RS10065 (HMPREF1038_02051) - 1864585..1864950 (-) 366 WP_000286415.1 DUF1033 family protein -
  HMPREF1038_RS10070 (HMPREF1038_02052) - 1865101..1866159 (-) 1059 WP_000649471.1 zinc-dependent alcohol dehydrogenase family protein -
  HMPREF1038_RS10075 (HMPREF1038_02053) nagA 1866322..1867473 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12222.42 Da        Isoelectric Point: 10.0305

>NTDB_id=53378 HMPREF1038_RS10050 WP_000738633.1 1862276..1862602(-) (comGC/cglC) [Streptococcus pneumoniae gamPNI0373]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKD
DGRITEEQVKAYKEYNDKNVGANRKVND

Nucleotide


Download         Length: 327 bp        

>NTDB_id=53378 HMPREF1038_RS10050 WP_000738633.1 1862276..1862602(-) (comGC/cglC) [Streptococcus pneumoniae gamPNI0373]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAGATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGAAAAGAATGAAGATGCTAGCCTAAGCAAGTTAAAAGAC
GATGGGCGAATCACGGAAGAACAGGTTAAAGCTTATAAAGAATACAATGATAAAAATGTAGGAGCAAATCGTAAAGTCAA
TGATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae TIGR4

95.37

100

0.954
  comGC/cglC Streptococcus pneumoniae Rx1

94.444

100

0.944
  comGC/cglC Streptococcus pneumoniae D39

94.444

100

0.944
  comGC/cglC Streptococcus pneumoniae R6

94.444

100

0.944
  comGC/cglC Streptococcus mitis SK321

91.667

100

0.917
  comGC/cglC Streptococcus mitis NCTC 12261

91.919

91.667

0.843
  comYC Streptococcus gordonii str. Challis substr. CH1

70.833

88.889

0.63
  comYC Streptococcus mutans UA159

61.765

94.444

0.583
  comYC Streptococcus mutans UA140

61.765

94.444

0.583
  comGC Lactococcus lactis subsp. cremoris KW2

55.882

94.444

0.528
  comYC Streptococcus suis isolate S10

66.667

75

0.5
  comGC Staphylococcus aureus MW2

48.837

79.63

0.389
  comGC Staphylococcus aureus N315

48.837

79.63

0.389
  comGC Latilactobacillus sakei subsp. sakei 23K

45.349

79.63

0.361

Multiple sequence alignment