Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   HMPREF1038_RS10055 Genome accession   NC_018630
Coordinates   1862604..1863620 (-) Length   338 a.a.
NCBI ID   WP_001844679.1    Uniprot ID   -
Organism   Streptococcus pneumoniae gamPNI0373     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1857604..1868620
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF1038_RS13455 (HMPREF1038_02038) - 1857681..1857812 (-) 132 WP_000768904.1 hypothetical protein -
  HMPREF1038_RS10010 (HMPREF1038_02039) - 1857813..1859003 (-) 1191 WP_000167766.1 acetate kinase -
  HMPREF1038_RS10015 (HMPREF1038_02040) comYH 1859054..1860007 (-) 954 WP_000345116.1 class I SAM-dependent methyltransferase Machinery gene
  HMPREF1038_RS12125 - 1860068..1860662 (-) 595 Protein_1886 class I SAM-dependent methyltransferase -
  HMPREF1038_RS10030 (HMPREF1038_02044) comGG/cglG 1860799..1861212 (-) 414 WP_000265631.1 competence type IV pilus minor pilin ComGG Machinery gene
  HMPREF1038_RS10035 (HMPREF1038_02045) comGF/cglF 1861190..1861651 (-) 462 WP_000250531.1 competence type IV pilus minor pilin ComGF Machinery gene
  HMPREF1038_RS10040 (HMPREF1038_02046) comGE/cglE 1861614..1861916 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  HMPREF1038_RS10045 (HMPREF1038_02047) comGD/cglD 1861879..1862283 (-) 405 WP_000588020.1 competence type IV pilus minor pilin ComGD Machinery gene
  HMPREF1038_RS10050 (HMPREF1038_02048) comGC/cglC 1862276..1862602 (-) 327 WP_000738633.1 comG operon protein ComGC Machinery gene
  HMPREF1038_RS10055 (HMPREF1038_02049) comGB/cglB 1862604..1863620 (-) 1017 WP_001844679.1 competence type IV pilus assembly protein ComGB Machinery gene
  HMPREF1038_RS10060 (HMPREF1038_02050) comGA/cglA/cilD 1863568..1864509 (-) 942 WP_001844680.1 competence type IV pilus ATPase ComGA Machinery gene
  HMPREF1038_RS10065 (HMPREF1038_02051) - 1864585..1864950 (-) 366 WP_000286415.1 DUF1033 family protein -
  HMPREF1038_RS10070 (HMPREF1038_02052) - 1865101..1866159 (-) 1059 WP_000649471.1 zinc-dependent alcohol dehydrogenase family protein -
  HMPREF1038_RS10075 (HMPREF1038_02053) nagA 1866322..1867473 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38535.63 Da        Isoelectric Point: 9.6162

>NTDB_id=53379 HMPREF1038_RS10055 WP_001844679.1 1862604..1863620(-) (comGB/cglB) [Streptococcus pneumoniae gamPNI0373]
MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLDRSALLDKQCVIQMRVGLSQGKSFSEMMESLGCSSAI
VTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLFFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
LGMAGLVSVLALLALTFYKRSSKMNVFSILARLPFIGIFVQTYLTAYYAREWGNMISQGMELTQIFQMMQEQGSQLFKEI
GQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=53379 HMPREF1038_RS10055 WP_001844679.1 1862604..1863620(-) (comGB/cglB) [Streptococcus pneumoniae gamPNI0373]
ATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAAGCAAAAAAATATCATCACCCTATTTAA
CAATCTCTTTTCTAGCGGTTTTCATCTGGTGGAGACTATCTCCTTTTTAGATAGGAGTGCTTTGTTGGACAAGCAGTGTG
TGATCCAGATGCGTGTGGGCTTGTCTCAGGGGAAATCATTCTCAGAAATGATGGAAAGTTTGGGATGTTCAAGTGCTATT
GTCACTCAGTTATCCCTAGCTGAAGTTCATGGCAATCTCCACCTGAGTTTGGGAAAGATAGAAGAATATCTGGACAATCT
GGCCAAGGTCAAGAAAAAATTGATTGAAGTAGCGACCTATCCCTTGATTTTGCTGTTTTTTCTTCTCTTAATCATGCTGG
GGCTACGGAATTACCTGCTCCCACAACTGGATAGTAGCAATATTGCCACCCGAATTATCGGTAATCTGCCCCAAATTTTT
CTAGGCATGGCAGGGCTTGTTTCCGTGCTTGCCCTTTTAGCACTAACTTTTTATAAAAGAAGTTCTAAGATGAATGTCTT
TTCTATCTTAGCACGCCTTCCCTTTATTGGAATCTTTGTGCAGACCTATTTGACAGCCTATTATGCACGTGAATGGGGGA
ATATGATTTCACAGGGAATGGAGTTGACGCAGATTTTTCAAATGATGCAGGAACAAGGTTCCCAGCTCTTTAAAGAAATC
GGTCAAGATCTGGCTCAAACCCTGAAAAATGGCCGTGAATTTTCTCAGACGATAGGAACCTATCCTTTCTTTAGGAAGGA
ATTGAGTCTCATCATAGAGTATGGGGAAGTTAAGTCCAAGCTGGGTAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGCCTTTTTTACCCGAGTCAACCGCACCATGAATTTGGTGCAGCCACTGGTTTTTATCTTTGTGGCACTGATTATCGTT
TTACTTTATGCGGCAATGCTCATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus pneumoniae Rx1

98.225

100

0.982
  comGB/cglB Streptococcus pneumoniae D39

98.225

100

0.982
  comGB/cglB Streptococcus pneumoniae R6

98.225

100

0.982
  comGB/cglB Streptococcus pneumoniae TIGR4

98.225

100

0.982
  comGB/cglB Streptococcus mitis SK321

94.379

100

0.944
  comGB/cglB Streptococcus mitis NCTC 12261

93.787

100

0.938
  comYB Streptococcus gordonii str. Challis substr. CH1

70.536

99.408

0.701
  comYB Streptococcus mutans UA140

58.044

93.787

0.544
  comYB Streptococcus mutans UA159

58.044

93.787

0.544
  comGB Lactococcus lactis subsp. cremoris KW2

50.898

98.817

0.503

Multiple sequence alignment