Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   HMPREF1038_RS10060 Genome accession   NC_018630
Coordinates   1863568..1864509 (-) Length   313 a.a.
NCBI ID   WP_001844680.1    Uniprot ID   -
Organism   Streptococcus pneumoniae gamPNI0373     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1858568..1869509
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF1038_RS10015 (HMPREF1038_02040) comYH 1859054..1860007 (-) 954 WP_000345116.1 class I SAM-dependent methyltransferase Machinery gene
  HMPREF1038_RS12125 - 1860068..1860662 (-) 595 Protein_1886 class I SAM-dependent methyltransferase -
  HMPREF1038_RS10030 (HMPREF1038_02044) comGG/cglG 1860799..1861212 (-) 414 WP_000265631.1 competence type IV pilus minor pilin ComGG Machinery gene
  HMPREF1038_RS10035 (HMPREF1038_02045) comGF/cglF 1861190..1861651 (-) 462 WP_000250531.1 competence type IV pilus minor pilin ComGF Machinery gene
  HMPREF1038_RS10040 (HMPREF1038_02046) comGE/cglE 1861614..1861916 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  HMPREF1038_RS10045 (HMPREF1038_02047) comGD/cglD 1861879..1862283 (-) 405 WP_000588020.1 competence type IV pilus minor pilin ComGD Machinery gene
  HMPREF1038_RS10050 (HMPREF1038_02048) comGC/cglC 1862276..1862602 (-) 327 WP_000738633.1 comG operon protein ComGC Machinery gene
  HMPREF1038_RS10055 (HMPREF1038_02049) comGB/cglB 1862604..1863620 (-) 1017 WP_001844679.1 competence type IV pilus assembly protein ComGB Machinery gene
  HMPREF1038_RS10060 (HMPREF1038_02050) comGA/cglA/cilD 1863568..1864509 (-) 942 WP_001844680.1 competence type IV pilus ATPase ComGA Machinery gene
  HMPREF1038_RS10065 (HMPREF1038_02051) - 1864585..1864950 (-) 366 WP_000286415.1 DUF1033 family protein -
  HMPREF1038_RS10070 (HMPREF1038_02052) - 1865101..1866159 (-) 1059 WP_000649471.1 zinc-dependent alcohol dehydrogenase family protein -
  HMPREF1038_RS10075 (HMPREF1038_02053) nagA 1866322..1867473 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -
  HMPREF1038_RS10080 (HMPREF1038_02054) - 1867626..1869443 (-) 1818 WP_001220841.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35579.46 Da        Isoelectric Point: 6.0083

>NTDB_id=53380 HMPREF1038_RS10060 WP_001844680.1 1863568..1864509(-) (comGA/cglA/cilD) [Streptococcus pneumoniae gamPNI0373]
MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIGSYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYA
YDQKMASLRLSTVGDYRGHESLVIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGETRDSETARAVVRASLTGATVFSTIHAKSIRGVY
ERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFANRDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=53380 HMPREF1038_RS10060 WP_001844680.1 1863568..1864509(-) (comGA/cglA/cilD) [Streptococcus pneumoniae gamPNI0373]
ATGGTTCAAGAAATTGCACAAGAAATCATTCGTTCAGCTCGGAAAAAAGGGACGCAGGATATTTATTTTGTCCCTAAGTT
AGACGCCTATGAGCTTCATATGAGGGTAGGAGACGAGCGCTGTAAAATTGGTAGCTATGATTTTGAAAAGTTTGCAGCCG
TTATCAGTCACTTTAAGTTTGTGGCGGGTATGAATGTGGGAGAAAAAAGACGTAGTCAACTGGGTTCCTGTGATTATGCC
TATGACCAGAAGATGGCGTCTCTACGTTTATCTACTGTAGGCGATTATCGGGGACATGAGAGTTTGGTTATCCGTTTGTT
GCACGATGAGGAGCAGGACTTGCATTTTTGGTTTCAGGATATTGAAGAATTAGGCAAGCAGTACAGGCAACGGGGACTCT
ATCTTTTTGCTGGCCCGGTTGGGAGTGGTAAGACGACCTTGATGCATGAATTGTCCAAGTCACTCTTTAAAGGACAGCAA
GTTATGTCCATCGAAGATCCTGTCGAAATCAAGCAGGACGACATGCTTCAGTTGCAGTTGAACGAAGCAATCGGCCTAAC
CTATGAAAATCTAATCAAACTTTCCTTGCGTCATCGACCAGATCTCTTGATTATCGGAGAAACTCGTGACAGCGAGACGG
CGCGTGCAGTGGTCAGAGCTAGTTTGACAGGTGCGACAGTCTTTTCAACCATTCACGCCAAGAGTATCCGAGGTGTTTAT
GAGCGTCTGCTGGAGTTGGGTGTGAGTGAAGAAGAATTGGCAGTTGTTCTGCAAGGAGTCTGCTACCAGAGATTAATCGG
GGGAGGAGGAATCGTTGACTTTGCAAACAGAGATTATCAAGAACACCAAGCAGCCAAGTGGAATGAGCAAATTGACCAGC
TTCTTAAAGATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

98.722

100

0.987
  comGA/cglA/cilD Streptococcus pneumoniae D39

98.722

100

0.987
  comGA/cglA/cilD Streptococcus pneumoniae R6

98.722

100

0.987
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

98.722

100

0.987
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

96.486

100

0.965
  comYA Streptococcus gordonii str. Challis substr. CH1

77.419

99.042

0.767
  comYA Streptococcus mutans UA159

65.595

99.361

0.652
  comYA Streptococcus mutans UA140

65.595

99.361

0.652
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.258

99.042

0.617
  comGA Lactococcus lactis subsp. cremoris KW2

54.487

99.681

0.543

Multiple sequence alignment