Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   JJN14_RS00740 Genome accession   NZ_CP067992
Coordinates   174180..174659 (+) Length   159 a.a.
NCBI ID   WP_201058581.1    Uniprot ID   -
Organism   Streptococcus mitis strain S022-V7-A3     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 169180..179659
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JJN14_RS00715 (JJN14_00715) - 169920..170795 (-) 876 WP_322107892.1 RluA family pseudouridine synthase -
  JJN14_RS00720 (JJN14_00720) pbp2a 170882..173077 (+) 2196 WP_201058659.1 penicillin-binding protein PBP2A -
  JJN14_RS00725 (JJN14_00725) rpmG 173130..173282 (+) 153 WP_001809375.1 50S ribosomal protein L33 -
  JJN14_RS00730 (JJN14_00730) secE 173292..173468 (+) 177 WP_001210990.1 preprotein translocase subunit SecE -
  JJN14_RS00735 (JJN14_00735) nusG 173523..174059 (+) 537 WP_000376740.1 transcription termination/antitermination protein NusG -
  JJN14_RS00740 (JJN14_00740) comX/sigX/comX2/sigX2 174180..174659 (+) 480 WP_201058581.1 sigma-70 family RNA polymerase sigma factor Regulator

Sequence

Protein


Download         Length: 159 a.a.        Molecular weight: 20059.78 Da        Isoelectric Point: 7.8963

>NTDB_id=526132 JJN14_RS00740 WP_201058581.1 174180..174659(+) (comX/sigX/comX2/sigX2) [Streptococcus mitis strain S022-V7-A3]
MFKELYKEVQGIVYKCRNEYYLHLWDLSDWDQEGMICLHELISREEDLVEDIPRLRKYFKTKFRNRILDHIRKQESQKRR
YDKEPYEEVGEISHRISEGGLWLDEYYLFHETLRDYRNKQSKDKQEELERVLRNERFRGRQRVLRDLRIVFKEFDIRTY

Nucleotide


Download         Length: 480 bp        

>NTDB_id=526132 JJN14_RS00740 WP_201058581.1 174180..174659(+) (comX/sigX/comX2/sigX2) [Streptococcus mitis strain S022-V7-A3]
ATGTTTAAAGAATTGTATAAAGAAGTCCAGGGGATTGTATATAAGTGTAGAAATGAATATTACCTTCATTTATGGGATCT
ATCGGATTGGGACCAAGAGGGGATGATTTGCTTACATGAATTGATTAGTAGAGAAGAAGATCTAGTAGAAGATATTCCTC
GTTTACGTAAATACTTCAAAACTAAATTCCGTAATCGAATTTTAGATCATATCCGTAAACAAGAAAGCCAGAAGCGTAGA
TATGATAAAGAACCTTATGAAGAAGTAGGTGAGATCAGTCATCGTATAAGCGAGGGAGGTCTGTGGCTAGATGAGTATTA
TCTCTTTCATGAGACACTAAGAGACTATAGAAACAAACAAAGTAAAGACAAACAAGAAGAGTTAGAACGCGTCTTAAGAA
ATGAACGCTTCCGAGGTCGTCAAAGAGTATTAAGAGACTTACGTATTGTATTTAAAGAGTTTGACATCCGTACATACTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

96.226

100

0.962
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

94.34

100

0.943
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

94.304

99.371

0.937
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

93.671

99.371

0.931
  comX/comX2 Streptococcus pneumoniae Rx1

91.824

100

0.918
  comX/comX1 Streptococcus pneumoniae Rx1

91.824

100

0.918
  comX/comX2 Streptococcus pneumoniae D39

91.824

100

0.918
  comX/comX1 Streptococcus pneumoniae D39

91.824

100

0.918
  comX/comX2 Streptococcus pneumoniae R6

91.824

100

0.918
  comX/comX1 Streptococcus pneumoniae R6

91.824

100

0.918
  comX/comX2 Streptococcus pneumoniae TIGR4

91.195

100

0.912
  comX/comX1 Streptococcus pneumoniae TIGR4

91.195

100

0.912
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

50

98.113

0.491
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

50

98.113

0.491
  comX/sigX Streptococcus suis D9

47.059

96.226

0.453
  comX/sigX Streptococcus suis isolate S10

47.059

96.226

0.453
  comX/sigX Streptococcus suis P1/7

47.059

96.226

0.453
  comX/sigX Streptococcus mutans UA159

46.405

96.226

0.447
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

42.282

93.711

0.396
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

42.282

93.711

0.396
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

42.282

93.711

0.396
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

42.282

93.711

0.396
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

41.447

95.597

0.396
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

41.447

95.597

0.396
  comX Streptococcus thermophilus LMG 18311

38.065

97.484

0.371
  comX Streptococcus thermophilus LMD-9

38.065

97.484

0.371
  comX Streptococcus sobrinus strain NIDR 6715-7

37.662

96.855

0.365
  comX Streptococcus salivarius SK126

37.419

97.484

0.365