Detailed information NTG0458845

Bioinformatically predicted

Overview

• Name: lytF
• Type: Regulator
• Locus tag: I6J12_RS10035
• Genome accession: NZ_CP068060
• Coordinates: 2075101..2077035 (-)
• Length: 644 a.a.
• NCBI ID: WP_003036896.1
• Uniprot ID: I0SBZ9
• Organism: Streptococcus anginosus strain FDAARGOS_1155
• Function: cell lysis (predicted from homology) Cell lysis

Genomic Context

Location: 2070101..2082035

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6J12_RS10015 (I6J12_10015)	purM	2071682..2072701 (+)	1020	WP_003037010.1	phosphoribosylformylglycinamidine cyclo-ligase	-
I6J12_RS10020 (I6J12_10020)	purN	2072701..2073255 (+)	555	WP_003036906.1	phosphoribosylglycinamide formyltransferase	-
I6J12_RS10025 (I6J12_10025)	-	2073310..2073480 (+)	171	WP_232609953.1	phosphoribosylaminoimidazolecarboxamide formyltransferase	-
I6J12_RS10030 (I6J12_10030)	purH	2073495..2075042 (+)	1548	WP_003036901.1	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	-
I6J12_RS10035 (I6J12_10035)	lytF	2075101..2077035 (-)	1935	WP_003036896.1	GBS Bsp-like repeat-containing protein	Regulator
I6J12_RS10040 (I6J12_10040)	purD	2077230..2078495 (+)	1266	WP_003036964.1	phosphoribosylamine--glycine ligase	-
I6J12_RS10045 (I6J12_10045)	-	2078485..2078919 (+)	435	WP_020999421.1	DUF523 domain-containing protein	-
I6J12_RS10050 (I6J12_10050)	purE	2079157..2079645 (+)	489	WP_003037056.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
I6J12_RS10055 (I6J12_10055)	purK	2079632..2080720 (+)	1089	WP_003036893.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
I6J12_RS10060 (I6J12_10060)	-	2080730..2080957 (+)	228	WP_003036973.1	hypothetical protein	-
I6J12_RS10065 (I6J12_10065)	-	2080968..2081930 (+)	963	WP_003036988.1	hypothetical protein	-

Sequence

Protein

• Length: 644 a.a.
• Molecular weight: 71159.00 Da
• Isoelectric Point: 8.5273

>NTDB_id=458845 I6J12_RS10035 WP_003036896.1 2075101..2077035(-) (lytF) [Streptococcus anginosus strain FDAARGOS_1155]
MKKYSQLFLLSSTILGIFSAQLTAQASEADNAQKSSNPAILASNITVNVSGNTASINYTRSQTQVPYTIYHAVWSDENGQ
DDIKWYSAPQTPTTAIDLRQHTGYGTFHVHTYININGKMVGLNGTTFKVEKPASGTVSTTVLGKTAQISFTRNKDQTNAN
ILHAVWSDEKGQDDIKWYTAGQDTTEIDLSNHKGYGVYHVHTYESKNGKMIGLNGTTFNLEKPNPTIQTSFPEPGIMDIQ
IKNVPKTIYKLTVPAWSDRNEQDDLQWYAATKNPDGSYNVRVELKKHNYDTGTYHIHLYGESYVKPEFTGLAGITAQVDA
DKLPSEEEQKPFFSVENINQEQGTYTVKVSETSKSKPIQSVRVPIWSTSNQSNIKWYAATNHGDGTFTAAFDIRNHQVLS
GTYTNHIYVKYKDGSEHSYVTDSVAMSAEKIKTKVSVAKRSTYLYEVTVTDAYGDGKISLPTWSEVNGQDDIQWYTATKA
GNGIYKFTIDTQKHTGSGLFHTHVYRNLNGQMIGLTGTSYQVEKPAISFQPNYAAATTYPKGQCTWGAKALAPWAGNYWG
NGGDWAASARRAGFKTGTTPQVGAIICWTDGGYGHVGVVTHVASNTRIQIQEANYAGKQYIGNFRGWFNPHAAGQGAVSY
IYPK

Nucleotide

• Length: 1935 bp

>NTDB_id=458845 I6J12_RS10035 WP_003036896.1 2075101..2077035(-) (lytF) [Streptococcus anginosus strain FDAARGOS_1155]
ATGAAGAAATACAGTCAATTATTTTTACTATCTAGCACTATTTTGGGCATTTTTTCTGCTCAACTAACTGCTCAAGCCTC
GGAAGCAGATAATGCTCAAAAAAGCTCAAATCCAGCAATTCTTGCTAGCAACATTACCGTCAATGTTTCTGGAAATACAG
CTTCTATTAACTACACACGCTCACAGACACAAGTTCCTTACACCATTTACCACGCTGTTTGGTCTGATGAAAATGGGCAA
GACGATATCAAATGGTATTCTGCGCCTCAGACACCAACTACAGCTATTGATTTGCGTCAGCACACTGGTTATGGAACCTT
TCATGTTCACACTTATATCAATATCAATGGAAAAATGGTTGGTTTAAACGGAACGACTTTCAAAGTAGAAAAACCAGCTA
GCGGCACGGTTTCTACAACCGTTTTAGGAAAGACTGCTCAAATATCCTTTACTCGAAACAAAGATCAAACAAATGCCAAT
ATTTTACACGCTGTTTGGTCTGACGAAAAAGGACAAGATGACATCAAGTGGTATACGGCAGGGCAAGACACAACAGAAAT
TGACTTATCCAATCATAAAGGATACGGTGTTTACCATGTTCATACTTATGAAAGTAAAAACGGAAAGATGATTGGATTAA
ATGGCACCACTTTTAACCTTGAAAAACCAAATCCTACTATTCAGACTAGCTTCCCTGAGCCTGGTATCATGGATATTCAG
ATCAAAAATGTTCCTAAAACAATCTACAAACTAACTGTTCCGGCTTGGTCTGACCGCAACGAACAGGATGATCTTCAATG
GTATGCAGCTACTAAAAATCCTGATGGAAGCTACAATGTTAGAGTTGAGCTAAAAAAACACAACTATGACACAGGAACTT
ATCACATTCATCTTTACGGAGAAAGCTATGTCAAACCAGAGTTTACTGGCTTAGCTGGAATCACTGCCCAAGTTGATGCT
GATAAATTGCCTTCTGAAGAAGAGCAAAAACCATTCTTCTCTGTTGAAAATATCAATCAAGAACAAGGGACTTATACCGT
CAAAGTTAGTGAAACTTCAAAGTCCAAGCCGATTCAATCCGTCCGAGTACCTATTTGGAGCACGAGCAATCAAAGCAATA
TCAAGTGGTATGCAGCCACTAATCACGGTGACGGAACATTTACGGCAGCATTTGATATTCGCAATCATCAAGTTTTGTCT
GGAACATATACCAATCATATTTATGTGAAATATAAAGACGGTAGCGAGCATAGTTACGTAACGGATTCGGTTGCTATGTC
CGCAGAAAAAATTAAAACCAAGGTATCTGTCGCTAAACGCTCAACTTATCTTTATGAGGTGACAGTGACAGATGCTTACG
GCGATGGCAAGATTAGCCTACCGACTTGGTCTGAAGTCAACGGCCAAGATGATATTCAGTGGTACACCGCTACTAAAGCT
GGAAATGGAATTTACAAATTCACAATTGATACGCAAAAACACACTGGCAGCGGGCTTTTCCATACACATGTCTACCGCAA
TCTCAACGGTCAAATGATTGGACTAACAGGTACGAGCTATCAAGTAGAGAAACCTGCTATCTCTTTCCAACCAAATTATG
CCGCAGCAACGACTTATCCAAAAGGGCAATGCACTTGGGGCGCCAAAGCTCTTGCACCTTGGGCTGGCAATTACTGGGGC
AATGGTGGTGATTGGGCTGCTAGCGCCAGACGAGCTGGTTTTAAAACCGGTACAACTCCACAAGTAGGGGCTATTATTTG
TTGGACAGACGGTGGTTACGGTCACGTTGGAGTTGTTACTCACGTTGCCTCAAACACACGCATTCAGATTCAAGAGGCCA
ACTACGCTGGAAAACAGTATATTGGCAACTTCCGCGGCTGGTTCAATCCTCATGCAGCTGGACAAGGAGCAGTTAGTTAC
ATTTATCCAAAATAA

Domains

Predicted by InterProScan.

• GBS Bsp-like repeat (GBS_Bsp-like) (437-518)

• GBS Bsp-like repeat (GBS_Bsp-like) (335-419)

• GBS Bsp-like repeat (GBS_Bsp-like) (151-218)

• GBS Bsp-like repeat (GBS_Bsp-like) (67-126)

• GBS Bsp-like repeat (GBS_Bsp-like) (232-302)

• CHAP domain (CHAP) (537-614)

3D structure

• AlphaFold DB: I0SBZ9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
lytF	Streptococcus gordonii strain NCTC7865	46.36	81.056	0.376
lytF	Streptococcus gordonii str. Challis substr. CH1	45.155	80.124	0.362